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epigallocatechin gallate and Lung Neoplasms

epigallocatechin gallate has been researched along with Lung Neoplasms in 95 studies

Research

Studies (95)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (10.53)	18.2507
2000's	25 (26.32)	29.6817
2010's	51 (53.68)	24.3611
2020's	9 (9.47)	2.80

Authors

Authors	Studies
Ali, A; Go, ML; Lam, Y; Tan, YJ; Tee, SY; Teo, JT; Xi, Y	1
Chen, F; Chen, N; Deng, X; Gu, Q; Li, Z; Wang, J	1
Armeni, T; Cianfruglia, L; Galeazzi, R; Laudadio, E; Minnelli, C; Mobbili, G	1
Datta, S; Sinha, D	1
Sheng, J; Sun, XL; Wang, LX; Wang, XJ; Wu, YL; Xiang, ZM; Xie, YR; Zhang, DY; Zhang, N; Zi, CT	1
Gao, J; Hao, S; Jiang, P; Li, F	1
Iida, K; Namiki, K; Rawangkan, A; Sakai, R; Sato, M; Suganuma, M; Wongsirisin, P; Yokoyama, S	1
Chen, BH; Hsieh, CH; Tsai, SY; Wang, CC; Wang, CY	1
Chen, W; Chen, X; Lu, Y; Tu, G; Wu, L; Zhang, L; Zheng, D	1
Chen, L; Feng, Q; Jiang, P; Li, S; Mageed, F; Ren, J; Wu, X; Xu, C; Zeb, F; Zhang, P	1
Chen, A; Feng, Q; Jiang, P; Mariyam, Z; Ul Haq, I; Wu, X; Zhou, M	1
Cao, J; Chen, G; Jiao, Y; Wu, J; Xing, L; Xue, J; Yang, H; Yu, C; Zhang, Q; Zhang, S; Zhu, W	1
Honda, Y; Ichihara, E; Kiura, K; Kubo, T; Murakami, T; Ninomiya, T; Ochi, N; Takigawa, N; Tanimoto, M; Yamane, H; Yasugi, M	1
Dhatwalia, SK; Dhawan, DK; Kumar, M	1
Chang, MC; Chen, CA; Chen, YL; Cheng, WF; Chiang, YC; Lin, HW; Sun, NY; Sun, WZ	1
Burlando, B; Martinotti, S; Ranzato, E	2
Chen, P; Gu, JJ; Li, Q; Qiao, KS; Sun, P	1
Chen, A; Chen, L; Feng, Q; Haq, IU; Jiang, P; Mariyam, Z; Wu, X; Xu, C; Zhou, M	2
Hu, DL; Huang, YF; Wang, D; Wang, G; Yu, J; Zhang, LH; Zhou, HH	1
Bhardwaj, V; Mandal, AKA	1
Chen, G; Jia, L; Li, X; Meng, X; Xing, L; Zhao, H; Zhao, X; Zhu, W	1
Chen, Z; Ma, G; Sun, H; Wang, X; Wei, X; Yang, J; Zhang, C	1
Choi, HK; Choi, KC; Jeon, H; Jeong, MH; Ko, H; Lee, SW; Ryu, SH; So, Y; Yoon, HG	1
Chen, Q; Hong, C; Jiang, Z; Jin, L; Li, C; Liu, J; Ma, Y; Wang, D; Wang, L; Xu, Y; Yu, F	1
Biffo, S; Burlando, B; Gallo, S; Martinotti, S; Mutti, L; Ranzato, E; Russo, MV; Volta, V	1
Deng, PB; Hu, CP; Li, YY; Xiong, Z; Yang, HP	1
Feng, Q; Huang, W; Shi, X; Wang, X; Yang, M; Zhou, DH	1
Chen, YC; Gao, Y; Jia, L; Li, B; Li, W; Tu, Y	1
de Bari, L; Manente, GA; Moro, L; Mutti, L; Rossi, L; Vacca, RA; Valenti, D	1
Feng, X; Feng, Y; Li, X; Liu, J; Tang, X; Zhou, K	1
Fukusato, T; Kubota, S; Muraguchi, T; Sakamoto, Y; Terashita, N	1
Forester, SC; Lambert, JD	1
Gao, F; Jiang, ZB; Jin, LY; Li, C; Liu, JX; Ma, YC; Xu, Y	1
Li, H; Sun, X; Xie, P; Xing, L; Yu, J; Zhang, X; Zhao, H; Zhu, W	1
Levine, A; Sun, Y; Yi, L	1
Chen, JX; Jin, H; Li, G; Lin, Y; Liu, A; Lu, G; Tu, S; Wang, H; Yang, CS	1
Chen, JX; Deng, Y; Wang, H; Yang, CS; Yang, MQ; Zhou, H	1
Khan, N; Mukhtar, H	1
Chen, X; Li, X; Sun, X; Xie, P; Xing, L; Yu, J; Zhao, H; Zhu, W	1
Cromie, MM; Gao, W	1
Feng, Q; Jiang, P; Li, A; Li, Y; Shen, X; Wang, P; Wang, X; Zhou, J	1
Arechaga-Ocampo, E; Astudillo-de la Vega, H; Carlos-Reyes, Á; Chávez, JD; Flores-Pérez, A; González-Pérez, A; López-Camarillo, C; Marchat, LA; Ramírez-Torres, N; Romero-Zamora, D; Ruiz-García, E; Sánchez, LL	1
An, J; Cao, LM; Gu, QH; Hu, CP; Li, JJ; Li, M; Yang, HP	1
Feng, Q; Huang, W; Jiang, P; Wang, X; Wu, X	1
Lioutikova, E; Manthey, J; Wang, H; Yang, MQ; Yang, W; Yoshigoe, K; Zhou, H	1
Chen, X; Huang, Z; Lei, Z; Luo, Z; Peng, C; Su, J; Zeng, W; Zhang, J; Zhang, X; Zhou, Y	1
Chen, Y; Geng, S; Huang, C; Jiang, Y; Li, X; Li, Y; Ma, X; Meng, Y; Wang, S; Wang, X; Wu, J; Wu, R; Xie, C; Yang, X; Zhong, C; Zhu, J; Zhu, M	1
Das, S; Manna, S; Mukherjee, S; Panda, CK; Roy, A	1
An, Y; Li, Z; Wang, S; Wang, Z	1
Sasaki, K; Yamauchi, R; Yoshida, K	1
Chen, DR; Chen, R; Fu, H; Hara, Y; He, J; Lubet, RA; Mei, F; Ryota, S; You, M; Zhang, Q	1
Bode, AM; Dong, Z	1
Gao, Z; Gong, M; Hung, MS; Jablon, DM; Lin, YC; Wang, T; Xu, Z; You, L; Zhi, X	1
Bigelow, RL; Burke, P; Cardelli, JA; Carroll, JL; Coleman, DT; Milligan, SA; Steffan, JJ; Williams, BJ	1
Fu, H; Hara, Y; He, J; Lubet, RA; Pan, J; Ryota, S; Wang, Y; You, M; Zhang, Q	1
Chen, YK; Guan, F; Hou, Z; Jin, H; Lee, MJ; Li, GX; Liu, B; Lu, G; Xiao, H; Yang, CS; Yang, Z; Yu, A	1
Bode, AM; Chae, JI; Dong, Z; Kim, DJ; Ma, WY; Shim, JH; Su, ZY; Yang, CS; Zhu, F	1
Han, W; Shi, M; Spivack, SD; Tan, XL; Tang, H	1
Go, VL; Jin, YS; Lu, QY; Mao, JT; Nie, WX; Rao, JY; Serio, KJ; Tsu, IH; Zhang, ZF	1
Bian, S; Wang, H; Yang, CS	1
Deng, YT; Lin, JK	1
Chie, EK; Kim, HJ; Kim, IA; Kim, IH; Kim, JH; Young, PD	1
Blancafort, A; Cufí, S; Haro, D; Marrero, PF; Oliveras, G; Puig, T; Relat, J	1
Hsu, SR; Kao, JY; Liu, LC; Tsai, TC; Tsao, TC; Wang, HC; Way, TD	1
He, L; Le, AD; Li, X; Shi, J; Tang, X; Zhang, E; Zhang, Q; Zhou, K	1
Chung, FL; Herzog, CR; Schwartz, J; Yang, YM	1
Anderson, MW; Lam, S; LeRiche, JC; Tichelaar, JW; Zhang, Y	1
Liu, J; Wei, D; Yang, J	1
Banerjee, S; Das, S; Manna, S; Panda, CK; Saha, P	1
Banerjee, S; Das, S; Ganguly, C; Manna, S; Panda, CK; Saha, P	1
Fujiki, H; Kurusu, M; Suganuma, M; Suzuki, K; Tasaki, E	1
Banerjee, S; Das, S; Manna, S; Panda, CK; Roy, A; Saha, P	1
Adhami, VM; Kweon, MH; Lee, JS; Mukhtar, H	1
Cook, J; Hitzman, CJ; McQuillan, J; Wang, Y; Wiedmann, TS; Yan, Y; You, M; Zhang, G	1
Li, YQ; Yang, XY; Yuan, JH	1
Baek, SJ; Kim, HJ; Lee, BD; Lee, JG; Moon, UY; Park, SH; Park, SY; Yoon, JH; Yoon, SH	1
Lambert, JD; Sang, S; Yang, CS	1
Isemura, M; Mukae, N; Narumi, K; Nukiwa, T; Ogata, K; Satoh, K; Suzuki, Y	1
Isemura, M; Motomiya, M; Narumi, K; Satoh, K; Suzuki, Y	1
Abe, S; Fujiki, H; Hara, K; Kim, SJ; Komori, A; Okabe, S; Suganuma, M; Yatsunami, J	1
Chung, FL; Eklind, KI; Morse, MA; Xu, Y	1
Fujiki, H; Hayashi, M; Komori, A; Okabe, S; Sueoka, E; Suganuma, M	1
Hara, Y; Imazawa, H; Isemura, M; Mita, T; Sazuka, M; Shoji, Y	1
Kim, K; Liao, J; Yang, CS; Yang, GY; Yurkow, EJ	1
Isemura, M; Isemura, S; Sazuka, M	1
Fujiki, H; Kai, Y; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M	1
Harada, M; Kataoka, M; Kiura, K; Matsuo, K; Mimoto, J; Takata, I; Ueoka, H; Yoshino, T	1
Aiello, FB; Brunetti, M; Caltagirone, S; Natali, PG; Piantelli, M; Poggi, A; Ranelletti, FO; Rossi, C	1
Fujiki, H; Fujimoto, N; Goto, Y; Imai, K; Matsuyama, S; Nakachi, K; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M	1
Fujiki, H; Fujimoto, N; Okabe, S; Sueoka, N; Suganuma, M	1
Chen, SH; Liang, YC; Lin, CL; Liu, JD; Tsai, SH	1
Fujiki, H; Fujimoto, N; Harada, M; Okabe, S; Sueoka, E; Sueoka, N; Suganuma, M	1
Amin, SG; Chung, FL; Han, C; Ho, CT; Xu, Y	1

Reviews

6 review(s) available for epigallocatechin gallate and Lung Neoplasms

Article	Year
Role of EGCG in Containing the Progression of Lung Tumorigenesis - A Multistage Targeting Approach. Nutrition and cancer, 2018, Volume: 70, Issue:3 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Camellia sinensis; Catechin; Cell Line, Tumor; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Molecular Structure; Signal Transduction	2018
Dietary agents for prevention and treatment of lung cancer. Cancer letters, 2015, Apr-10, Volume: 359, Issue:2 Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Curcumin; Flavonoids; Flavonols; Humans; Indoles; Isothiocyanates; Lung Neoplasms; Plant Extracts; Polyphenols	2015
Epigallocatechin 3-gallate and green tea catechins: United they work, divided they fail. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:6 Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availability; Catechin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Humans; Lung Neoplasms; Mice; Mice, Inbred A; Models, Biological; Neoplasms; Phenols; Phytotherapy; Polyphenols; Protein Binding; Tea	2009
Tea and cancer prevention: studies in animals and humans. The Journal of nutrition, 2003, Volume: 133, Issue:10 Topics: Animals; Apoptosis; Caffeine; Catechin; Clinical Trials as Topic; Flavonoids; Humans; Lung Neoplasms; Mice; Mouth Neoplasms; Neoplasms; Phenols; Polyphenols; Rats; Smoking; Tea	2003
Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis by compounds derived from cruciferous vegetables and green tea. Annals of the New York Academy of Sciences, 1993, May-28, Volume: 686 Topics: Adenoma; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catechin; DNA; DNA Damage; Indoles; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Rats; Rats, Inbred F344; Tea; Thiocyanates; Vegetables	1993
Cancer prevention with green tea and monitoring by a new biomarker, hnRNP B1. Mutation research, 2001, Sep-01, Volume: 480-481 Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinoma, Squamous Cell; Catechin; Chemoprevention; Cohort Studies; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Intestinal Neoplasms; Japan; Lung Neoplasms; Male; Mice; Mice, Mutant Strains; Okadaic Acid; Oligonucleotide Array Sequence Analysis; Prospective Studies; Ribonucleoproteins; Sulindac; Tea; Tumor Cells, Cultured	2001

Trials

3 trial(s) available for epigallocatechin gallate and Lung Neoplasms

Article	Year
A prospective, three-arm, randomized trial of EGCG for preventing radiation-induced esophagitis in lung cancer patients receiving radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2019, Volume: 137 Topics: Acute Disease; Aged; Carcinoma, Non-Small-Cell Lung; Catechin; Chemoradiotherapy; Esophagitis; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Radiation Injuries; Radiation-Protective Agents; Radiotherapy Dosage	2019
A phase I study of concurrent chemotherapy and thoracic radiotherapy with oral epigallocatechin-3-gallate protection in patients with locally advanced stage III non-small-cell lung cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:1 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Catechin; Chemoradiotherapy; Cisplatin; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Radiotherapy Dosage	2014
A prospective phase II trial of EGCG in treatment of acute radiation-induced esophagitis for stage III lung cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 114, Issue:3 Topics: Adult; Aged; Catechin; Esophagitis; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Quality of Life; Radiation Injuries	2015

Other Studies

86 other study(ies) available for epigallocatechin gallate and Lung Neoplasms

Article	Year
Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cells. European journal of medicinal chemistry, 2019, Nov-15, Volume: 182 Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; Fatty Acid Synthase, Type I; Gallic Acid; Humans; Lung Neoplasms; Molecular Structure; Stilbenes; Structure-Activity Relationship	2019
Effect of EGCG on bronchial epithelial cell premalignant lesions induced by cigarette smoke and on its CYP1A1 expression. International journal of molecular medicine, 2021, Volume: 48, Issue:6 Topics: Animals; Bronchi; Catechin; Cell Line; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Rats; Rats, Sprague-Dawley; Signal Transduction; Smoke; Smoking	2021
Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer. International journal of molecular sciences, 2021, Oct-31, Volume: 22, Issue:21 Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Catechin; ErbB Receptors; Humans; Lung Neoplasms; Neoplasm Proteins; Signal Transduction	2021
Low dose epigallocatechin-3-gallate revives doxorubicin responsiveness by a redox-sensitive pathway in A549 lung adenocarcinoma cells. Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:4 Topics: A549 Cells; Adenocarcinoma of Lung; Catechin; Doxorubicin; Humans; Lung Neoplasms; Oxidation-Reduction	2022
Dimeric-(-)-epigallocatechin-3-gallate inhibits the proliferation of lung cancer cells by inhibiting the EGFR signaling pathway. Chemico-biological interactions, 2022, Sep-25, Volume: 365 Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Lung Neoplasms; Signal Transduction	2022
EGCG alleviates obesity-exacerbated lung cancer progression by STAT1/SLC7A11 pathway and gut microbiota. The Journal of nutritional biochemistry, 2023, Volume: 120 Topics: Animals; Carcinogenesis; Diet, High-Fat; Gastrointestinal Microbiome; Leptin; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Obesity; Urethane	2023
(-)-Epigallocatechin gallate inhibits stemness and tumourigenicity stimulated by AXL receptor tyrosine kinase in human lung cancer cells. Scientific reports, 2020, 02-12, Volume: 10, Issue:1 Topics: Animals; Anticarcinogenic Agents; Axl Receptor Tyrosine Kinase; Carcinogenesis; Catechin; Cell Line, Tumor; Female; Humans; Lung Neoplasms; Mice, SCID; Neoplastic Stem Cells; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases	2020
Anticancer effects of epigallocatechin-3-gallate nanoemulsion on lung cancer cells through the activation of AMP-activated protein kinase signaling pathway. Scientific reports, 2020, 03-20, Volume: 10, Issue:1 Topics: AMP-Activated Protein Kinases; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Humans; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction	2020
Enhanced Chemotherapeutic Efficacy of PLGA-Encapsulated Epigallocatechin Gallate (EGCG) Against Human Lung Cancer. International journal of nanomedicine, 2020, Volume: 15 Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Drug Liberation; Endocytosis; Humans; Lung Neoplasms; Nanoparticles; NF-kappa B; Polylactic Acid-Polyglycolic Acid Copolymer	2020
Epigallocatechin‑3‑gallate inhibits self‑renewal ability of lung cancer stem‑like cells through inhibition of CLOCK. International journal of molecular medicine, 2020, Volume: 46, Issue:6 Topics: Animals; Catechin; Cell Line, Tumor; Cell Self Renewal; Circadian Rhythm; CLOCK Proteins; Female; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Up-Regulation; Wnt Signaling Pathway	2020
NEAT1 acts as an inducer of cancer stem cell-like phenotypes in NSCLC by inhibiting EGCG-upregulated CTR1. Journal of cellular physiology, 2018, Volume: 233, Issue:6 Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Catechin; Cation Transport Proteins; Copper Transporter 1; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplastic Stem Cells; Phenotype; RNA, Long Noncoding; Wnt Signaling Pathway	2018
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway. International journal of biological sciences, 2017, Volume: 13, Issue:12 Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line; Cell Line, Tumor; Female; Heme Oxygenase-1; Humans; Lung Neoplasms; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Promoter Regions, Genetic; Reactive Oxygen Species; Signal Transduction	2017
Effects of (-)-epigallocatechin-3-gallate on EGFR- or Fusion Gene-driven Lung Cancer Cells. Acta medica Okayama, 2017, Volume: 71, Issue:6 Topics: Anaplastic Lymphoma Kinase; Animals; Blood Proteins; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Crizotinib; Disease Models, Animal; ErbB Receptors; Female; Gene Rearrangement; Heterografts; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Proteins, Fusion; Polyphenols; Protein S; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Tea	2017
Immuno-modulators enhance antigen-specific immunity and anti-tumor effects of mesothelin-specific chimeric DNA vaccine through promoting DC maturation. Cancer letters, 2018, 07-01, Volume: 425 Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Catechin; Cell Line, Tumor; Connective Tissue Growth Factor; Dendritic Cells; Drug Synergism; Female; GPI-Linked Proteins; Lung Neoplasms; Mesothelin; Mesothelioma; Mesothelioma, Malignant; Mice; Poly I-C; Treatment Outcome; Vaccines, DNA; Xenograft Model Antitumor Assays	2018
(-)- Epigallocatechin-3-gallate induces GRP78 accumulation in the ER and shifts mesothelioma constitutive UPR into proapoptotic ER stress. Journal of cellular physiology, 2018, Volume: 233, Issue:10 Topics: Apoptosis; Catechin; Cell Survival; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Homeostasis; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Molecular Chaperones	2018
Study of EGCG induced apoptosis in lung cancer cells by inhibiting PI3K/Akt signaling pathway. European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:14 Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction	2018
Epigallocatechin-3-gallate inhibited cancer stem cell-like properties by targeting hsa-mir-485-5p/RXRα in lung cancer. Journal of cellular biochemistry, 2018, Volume: 119, Issue:10 Topics: A549 Cells; Analysis of Variance; Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Down-Regulation; Gene Knockdown Techniques; Gene Silencing; HEK293 Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Molecular Mimicry; Neoplastic Stem Cells; Retinoid X Receptor alpha; Signal Transduction; Transfection; Up-Regulation; Xenograft Model Antitumor Assays	2018
EGCG inhibits CSC-like properties through targeting miR-485/CD44 axis in A549-cisplatin resistant cells. Molecular carcinogenesis, 2018, Volume: 57, Issue:12 Topics: A549 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Neoplastic Stem Cells; Xenograft Model Antitumor Assays	2018
Epigallocatechin‑3‑gallate modulates long non‑coding RNA and mRNA expression profiles in lung cancer cells. Molecular medicine reports, 2019, Volume: 19, Issue:3 Topics: Catechin; Cell Line, Tumor; Computational Biology; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; RNA, Long Noncoding; RNA, Messenger; Signal Transduction	2019
Next-Generation Sequencing Reveals the Role of Epigallocatechin-3-Gallate in Regulating Putative Novel and Known microRNAs Which Target the MAPK Pathway in Non-Small-Cell Lung Cancer A549 Cells. Molecules (Basel, Switzerland), 2019, Jan-21, Volume: 24, Issue:2 Topics: Carcinoma, Non-Small-Cell Lung; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Humans; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Nucleic Acid Conformation; Reproducibility of Results; Transcriptome	2019
A Generic Coordination Assembly-Enabled Nanocoating of Individual Tumor Cells for Personalized Immunotherapy. Advanced healthcare materials, 2019, Volume: 8, Issue:17 Topics: Animals; Antigens; Body Weight; Bone Marrow Cells; Catechin; Cell Line, Tumor; Cell Survival; Dendritic Cells; Female; Humans; Immunotherapy; Lung Neoplasms; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Photoelectron Spectroscopy; Precision Medicine	2019
TGF-β1-induced epithelial-mesenchymal transition and acetylation of Smad2 and Smad3 are negatively regulated by EGCG in human A549 lung cancer cells. Cancer letters, 2013, Jul-10, Volume: 335, Issue:1 Topics: Acetylation; Anticarcinogenic Agents; Antigens, CD; Cadherins; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; p300-CBP Transcription Factors; Protein Binding; Protein Processing, Post-Translational; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1; Vimentin	2013
Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells. Oncology reports, 2013, Volume: 29, Issue:5 Topics: Catechin; Cell Line; Cell Line, Tumor; Cell Nucleus; HEK293 Cells; Humans; Lung Neoplasms; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-mdm2; Tea; Transcription, Genetic; Tumor Suppressor Protein p53; Ubiquitination; Up-Regulation	2013
Preclinical demonstration of synergistic Active Nutrients/Drug (AND) combination as a potential treatment for malignant pleural mesothelioma. PloS one, 2013, Volume: 8, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Inbred NOD; Mice, SCID; Pleural Neoplasms; Signal Transduction; Xenograft Model Antitumor Assays	2013
Treatment with EGCG in NSCLC leads to decreasing interstitial fluid pressure and hypoxia to improve chemotherapy efficacy through rebalance of Ang-1 and Ang-2. Chinese journal of natural medicines, 2013, Volume: 11, Issue:3 Topics: Angiogenesis Inhibitors; Angiopoietin-1; Angiopoietin-2; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Chemotherapy, Adjuvant; Cisplatin; Drug Therapy, Combination; Extracellular Fluid; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Oxygen	2013
Combination of low concentration of (-)-epigallocatechin gallate (EGCG) and curcumin strongly suppresses the growth of non-small cell lung cancer in vitro and in vivo through causing cell cycle arrest. International journal of molecular sciences, 2013, Jun-05, Volume: 14, Issue:6 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Clone Cells; Curcumin; Cyclin B1; Cyclin D1; DNA Replication; Female; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude	2013
Enhancement of (-)-epigallocatechin-3-gallate and theaflavin-3-3'-digallate induced apoptosis by ascorbic acid in human lung adenocarcinoma SPC-A-1 cells and esophageal carcinoma Eca-109 cells via MAPK pathways. Biochemical and biophysical research communications, 2013, Aug-23, Volume: 438, Issue:2 Topics: Adenocarcinoma; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Biflavonoids; Caspase 3; Caspase 9; Catechin; Cell Line, Tumor; Enzyme Inhibitors; Esophageal Neoplasms; Gallic Acid; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System	2013
Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells. Biochimica et biophysica acta, 2013, Volume: 1832, Issue:12 Topics: Adenosine Triphosphate; Apoptosis; Catalase; Catechin; Cell Cycle; Cell Proliferation; Cells, Cultured; Cytochromes c; Electron Transport Complex I; Electron Transport Complex II; Epithelial Cells; Humans; Immunoblotting; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mitochondria; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation; Pleural Neoplasms; Reactive Oxygen Species; Superoxide Dismutase	2013
Epigallocatechin-3-gallate inhibits IGF-I-stimulated lung cancer angiogenesis through downregulation of HIF-1α and VEGF expression. Journal of nutrigenetics and nutrigenomics, 2013, Volume: 6, Issue:3 Topics: Base Sequence; Catechin; Cell Line, Tumor; DNA Primers; Down-Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin-Like Growth Factor I; Lung Neoplasms; Neovascularization, Pathologic; Real-Time Polymerase Chain Reaction; Vascular Endothelial Growth Factor A	2013
Effects of epigallocatechin-3-gallate (EGCG) on A549 lung cancer tumor growth and angiogenesis. Bioscience, biotechnology, and biochemistry, 2013, Volume: 77, Issue:9 Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endostatins; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; RNA, Messenger; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays	2013
Synergistic inhibition of lung cancer cell lines by (-)-epigallocatechin-3-gallate in combination with clinically used nitrocatechol inhibitors of catechol-O-methyltransferase. Carcinogenesis, 2014, Volume: 35, Issue:2 Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzophenones; Blotting, Western; Catechin; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Cycle; Cell Proliferation; Cell-Free System; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Humans; Lung Neoplasms; Male; Mice; Nitriles; Nitro Compounds; Nitrophenols; Oxidative Stress; Reactive Oxygen Species; Tolcapone; Tumor Cells, Cultured	2014
Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway. Oncology reports, 2014, Volume: 31, Issue:3 Topics: Antineoplastic Agents; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ErbB Receptors; G1 Phase Cell Cycle Checkpoints; Gene Expression; Gene Knockdown Techniques; Humans; Lung Neoplasms; Signal Transduction	2014
Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells. Oncotarget, 2014, Oct-15, Volume: 5, Issue:19 Topics: Animals; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neoplasm Transplantation; Phthalimides; Tryptophan; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2014
NNK-induced DNA methyltransferase 1 in lung tumorigenesis in A/J mice and inhibitory effects of (-)-epigallocatechin-3-gallate. Nutrition and cancer, 2015, Volume: 67, Issue:1 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Bronchi; Carcinogenesis; Carcinogens; Catechin; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Lung; Lung Neoplasms; Mice, Inbred A; Neoplasm Proteins; Nitrosamines; Promoter Regions, Genetic; Respiratory Mucosa	2015
Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer. BMC genomics, 2014, Volume: 15 Suppl 11 Topics: Animals; Anticarcinogenic Agents; Camellia sinensis; Carcinogens; Catechin; Cell Cycle Proteins; Female; Gene Expression Regulation; Lung Neoplasms; Mice; MicroRNAs; Mitogen-Activated Protein Kinases; NF-kappa B; Nitrosamines; Polyphenols; Proto-Oncogene Proteins c-akt	2014
Epigallocatechin-3-gallate enhances the therapeutic effects of leptomycin B on human lung cancer a549 cells. Oxidative medicine and cellular longevity, 2015, Volume: 2015 Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cytochrome P-450 CYP3A; Down-Regulation; Fatty Acids, Unsaturated; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Reactive Oxygen Species; Superoxide Dismutase; Survivin; Up-Regulation	2015
EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cells. Scientific reports, 2015, Jun-05, Volume: 5 Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Transport Proteins; Mice, Inbred BALB C; Mice, Nude; Proteolysis; Xenograft Model Antitumor Assays	2015
Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non-small cells lung cancer to chemotherapy. Proteomics. Clinical applications, 2016, Volume: 10, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Proteomics; Structure-Activity Relationship; Tumor Cells, Cultured	2016
EGCG induces lung cancer A549 cell apoptosis by regulating Ku70 acetylation. Oncology reports, 2016, Volume: 35, Issue:4 Topics: A549 Cells; Acetylation; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Catechin; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Ku Autoantigen; Lung Neoplasms	2016
NEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells. Oncotarget, 2016, Jul-12, Volume: 7, Issue:28 Topics: A549 Cells; Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cation Transport Proteins; Cell Proliferation; Chemotherapy, Adjuvant; Cisplatin; Copper Transporter 1; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Microscopy, Fluorescence; RNA Interference; RNA, Long Noncoding; RNA, Small Interfering; Up-Regulation; Xenograft Model Antitumor Assays	2016
The up-regulation of Myb may help mediate EGCG inhibition effect on mouse lung adenocarcinoma. Human genomics, 2016, 07-25, Volume: 10 Suppl 2 Topics: Adenocarcinoma; Animals; Antioxidants; Catechin; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Kruppel-Like Transcription Factors; Lung; Lung Neoplasms; Mice, Inbred Strains; MicroRNAs; Proto-Oncogene Proteins c-myb; Up-Regulation	2016
Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity. Oncotarget, 2016, Nov-29, Volume: 7, Issue:48 Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; MAP Kinase Kinase Kinases; Melanoma; Mice, Inbred BALB C; Molecular Docking Simulation; Neoplasm Invasiveness; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Conformation; Signal Transduction; Skin Neoplasms; Structure-Activity Relationship; TNF Receptor-Associated Factor 6; Transfection; Tumor Burden; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination	2016
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells. Biochemical and biophysical research communications, 2017, Jan-01, Volume: 482, Issue:1 Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Neoplastic Stem Cells; Wnt Signaling Pathway	2017
Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1. The Journal of nutritional biochemistry, 2009, Volume: 20, Issue:5 Topics: Animals; Apoptosis; Benzo(a)pyrene; Biflavonoids; Catechin; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Female; Flavonoids; Lung; Lung Neoplasms; Male; Mice; Phenols; Polyphenols; Proto-Oncogene Proteins c-myc; ras Proteins; Tea; Tumor Suppressor Protein p53	2009
[Inhibition of (-)epigallocatechin gallate on dimethylarsinic acid promoting lung tumorigenesis through the induction of oxidative stress in mice]. Wei sheng yan jiu = Journal of hygiene research, 2008, Volume: 37, Issue:6 Topics: Animals; Antineoplastic Agents; Cacodylic Acid; Catechin; Lung Neoplasms; Male; Mice; Oxidative Stress	2008
Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549. Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:5 Topics: Apoptosis; Caspase 3; Caspase 7; Catechin; Cell Line, Tumor; Cell Survival; Flavonoids; Humans; Luciferases; Lung Neoplasms; Phenols; Polyphenols; Signal Transduction; Tea; Tumor Suppressor Protein p53	2009
Lung cancer inhibitory effect of epigallocatechin-3-gallate is dependent on its presence in a complex mixture (polyphenon E). Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:6 Topics: Adenoma; Aerosols; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Biological Availability; Catechin; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lung Neoplasms; Mice; Mice, Inbred A; Tea	2009
Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells. Anticancer research, 2009, Volume: 29, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Anticarcinogenic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Lung Neoplasms; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urokinase-Type Plasminogen Activator	2009
The green tea polyphenol EGCG potentiates the antiproliferative activity of c-Met and epidermal growth factor receptor inhibitors in non-small cell lung cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Aug-01, Volume: 15, Issue:15 Topics: Animals; Anticarcinogenic Agents; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Humans; Indoles; Lung Neoplasms; Male; Mice; Mice, SCID; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Quinazolines; Sulfonamides; Xenograft Model Antitumor Assays	2009
Effect of dietary Polyphenon E and EGCG on lung tumorigenesis in A/J Mice. Pharmaceutical research, 2010, Volume: 27, Issue:6 Topics: Animals; Anticarcinogenic Agents; Catechin; Chemoprevention; Female; Lung; Lung Neoplasms; Mice	2010
Pro-oxidative activities and dose-response relationship of (-)-epigallocatechin-3-gallate in the inhibition of lung cancer cell growth: a comparative study in vivo and in vitro. Carcinogenesis, 2010, Volume: 31, Issue:5 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Deoxyguanosine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Histones; Humans; Lung Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Reactive Oxygen Species; Xenograft Model Antitumor Assays	2010
Epigallocatechin gallate suppresses lung cancer cell growth through Ras-GTPase-activating protein SH3 domain-binding protein 1. Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:5 Topics: Anticarcinogenic Agents; Blotting, Western; Carrier Proteins; Catechin; Cell Line, Tumor; Cell Proliferation; DNA Helicases; Humans; Immunoprecipitation; Lung Neoplasms; Poly-ADP-Ribose Binding Proteins; RNA Helicases; RNA Recognition Motif Proteins; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; src Homology Domains	2010
Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells. The Journal of nutrition, 2010, Volume: 140, Issue:8 Topics: Anticarcinogenic Agents; Brassica; Bronchi; Camellia sinensis; Catechin; Cell Division; Cell Line; Cell Line, Tumor; Epithelial Cells; Gene Expression; Glutathione S-Transferase pi; Humans; Isothiocyanates; Lung; Lung Neoplasms; NAD(P)H Dehydrogenase (Quinone); Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfoxides; Thiocyanates	2010
White tea extract induces apoptosis in non-small cell lung cancer cells: the role of peroxisome proliferator-activated receptor-{gamma} and 15-lipoxygenases. Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:9 Topics: Anilides; Apoptosis; Arachidonate 15-Lipoxygenase; Carcinoma, Non-Small-Cell Lung; Catechin; Drug Evaluation, Preclinical; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Hydroxyeicosatetraenoic Acids; Lung Neoplasms; Plant Extracts; PPAR gamma; Tea; Tumor Cells, Cultured	2010
In vitro screening of synergistic ascorbate-drug combinations for the treatment of malignant mesothelioma. Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:8 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Mesothelioma; Neutral Red	2011
Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1α. Carcinogenesis, 2011, Volume: 32, Issue:12 Topics: Animals; Blotting, Western; Catechin; Cell Division; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Lung Neoplasms; Mice; MicroRNAs; Tea; Up-Regulation	2011
EGCG inhibits the invasion of highly invasive CL1-5 lung cancer cells through suppressing MMP-2 expression via JNK signaling and induces G2/M arrest. Journal of agricultural and food chemistry, 2011, Dec-28, Volume: 59, Issue:24 Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Tea	2011
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity. Radiation oncology (London, England), 2012, Mar-20, Volume: 7 Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine	2012
Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer. BMC cancer, 2012, Jul-06, Volume: 12 Topics: 4-Butyrolactone; Adenocarcinoma; Adenocarcinoma of Lung; Analysis of Variance; Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Catechin; Cell Line, Tumor; Fatty Acid Synthases; Fatty Acids; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Random Allocation; Signal Transduction; Weight Loss; Xenograft Model Antitumor Assays	2012
EGCG inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition via the inhibition of Smad2 and Erk1/2 signaling pathways in nonsmall cell lung cancer cells. Journal of agricultural and food chemistry, 2012, Oct-03, Volume: 60, Issue:39 Topics: Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; MAP Kinase Signaling System; Plant Extracts; Smad2 Protein; Transforming Growth Factor beta	2012
(-)-Epigallocatechin-3-gallate inhibits human papillomavirus (HPV)-16 oncoprotein-induced angiogenesis in non-small cell lung cancer cells by targeting HIF-1α. Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Gene Expression; Human papillomavirus 16; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Oncogene Proteins; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Repressor Proteins; Signal Transduction; Transfection; Vascular Endothelial Growth Factor A	2013
Activation of the Akt/nuclear factor-kappaB signaling axis in developing lung neoplasia. Chest, 2004, Volume: 125, Issue:5 Suppl Topics: Anticarcinogenic Agents; Budesonide; Catechin; Cell Line, Tumor; Eflornithine; Humans; Lung Neoplasms; Neoplasm Proteins; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt	2004
Repressions of MMP-9 expression and NF-kappa B localization are involved in inhibition of lung carcinoma 95-D cell invasion by (-)-epigallocatechin-3-gallate. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2005, Volume: 59, Issue:3 Topics: Antioxidants; Blotting, Western; Catechin; Down-Regulation; Humans; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Neoplasm Metastasis; NF-kappa B; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured	2005
Black tea polyphenols suppress cell proliferation and induce apoptosis during benzo(a)pyrene-induced lung carcinogenesis. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2005, Volume: 14, Issue:3 Topics: Animals; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcinoma in Situ; Catechin; Cell Proliferation; Lung Neoplasms; Mice; Tea	2005
Black tea extract can modulate protein expression of H-ras, c-Myc, p53, and Bcl-2 genes during pulmonary hyperplasia, dysplasia, and carcinoma in situ. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2005, Volume: 24, Issue:3 Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Biflavonoids; Carcinoma in Situ; Catechin; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Hyperplasia; Lung; Lung Neoplasms; Male; Mice; Plant Extracts; Proto-Oncogene Proteins; Proto-Oncogenes; Tea	2005
Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene. International journal of cancer, 2006, Jul-01, Volume: 119, Issue:1 Topics: Anticarcinogenic Agents; Blotting, Western; Catechin; Celecoxib; Cell Line, Tumor; Cyclooxygenase Inhibitors; Drug Synergism; Flavonoids; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase Kinases; Phenols; Plant Extracts; Polymerase Chain Reaction; Polyphenols; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tea; Transcription Factor CHOP; Up-Regulation	2006
Differential alterations in metabolic pattern of the spliceosomal UsnRNAs during pre-malignant lung lesions induced by benzo(a)pyrene: modulation by tea polyphenols. Molecular and cellular biochemistry, 2006, Volume: 289, Issue:1-2 Topics: Animals; Benzo(a)pyrene; Catechin; Flavonoids; Lung; Lung Neoplasms; Mice; Phenols; Polyphenols; Precancerous Conditions; RNA, Small Nuclear; Spliceosomes; Tea	2006
Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate. The Journal of biological chemistry, 2006, Nov-03, Volume: 281, Issue:44 Topics: Adenocarcinoma; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Heme Oxygenase-1; Humans; Lung Neoplasms; NF-E2-Related Factor 2; Oxidation-Reduction; Protein Kinase C-alpha; Response Elements; RNA, Small Interfering; Sensitivity and Specificity; Transcriptional Activation	2006
Chemopreventive effect of aerosolized polyphenon E on lung tumorigenesis in A/J mice. Neoplasia (New York, N.Y.), 2007, Volume: 9, Issue:5 Topics: Aerosols; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Catechin; Female; Lung Neoplasms; Mice	2007
Inhibition of epigallocatechin gallate on orthotopic colon cancer by upregulating the Nrf2-UGT1A signal pathway in nude mice. Pharmacology, 2007, Volume: 80, Issue:4 Topics: Animals; Anticarcinogenic Agents; Catechin; Colonic Neoplasms; Glucuronosyltransferase; HT29 Cells; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; RNA, Messenger; Signal Transduction	2007
Epigallocatechin-3-gallate inhibits interleukin-1beta-induced MUC5AC gene expression and MUC5AC secretion in normal human nasal epithelial cells. The Journal of nutritional biochemistry, 2008, Volume: 19, Issue:8 Topics: Catechin; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Humans; Interleukin-1beta; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mucin 5AC; Mucins; Nasal Mucosa; Promoter Regions, Genetic; Signal Transduction; Tumor Cells, Cultured	2008
N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct. Free radical biology & medicine, 2008, Mar-15, Volume: 44, Issue:6 Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Flow Cytometry; Humans; Lung Neoplasms; Mice; Radiation-Protective Agents	2008
Effects of catechins on the mouse tumor cell adhesion to fibronectin. Planta medica, 1995, Volume: 61, Issue:5 Topics: Animals; Binding Sites; Catechin; Cell Adhesion; Fibronectins; Lung Neoplasms; Melanoma, Experimental; Mice; Tumor Cells, Cultured	1995
Effects of catechins on the mouse lung carcinoma cell adhesion to the endothelial cells. Cell biology international, 1993, Volume: 17, Issue:6 Topics: Animals; Catechin; Cattle; Cell Adhesion; Cell Survival; Cells, Cultured; Endothelium, Vascular; Flavonoids; Lung Neoplasms; Mice; Mice, Inbred C57BL; Structure-Activity Relationship; Tumor Cells, Cultured	1993
Anticarcinogenic activity of green tea polyphenols. Japanese journal of clinical oncology, 1993, Volume: 23, Issue:3 Topics: Animals; Antineoplastic Agents; Catechin; Dose-Response Relationship, Drug; Doxorubicin; Estrogens; Flavonoids; Lung Neoplasms; Lyngbya Toxins; Mammary Neoplasms, Experimental; Phenols; Plant Extracts; Polymers; Protein Kinase C; Tea; Tumor Cells, Cultured	1993
Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols. Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:7 Topics: Antineoplastic Agents; Catechin; Cell Cycle; Cell Division; Humans; Lung Neoplasms; Phenols; Tea; Tritium; Tumor Cells, Cultured	1997
Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins. Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:9 Topics: Animals; Antioxidants; Biflavonoids; Carcinoma; Catechin; Free Radical Scavengers; Gallic Acid; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Mice; Tea; Tumor Cells, Cultured	1997
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis, 1998, Volume: 19, Issue:4 Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Colonic Neoplasms; Humans; Lung Neoplasms; Superoxide Dismutase; Tea; Tumor Cells, Cultured	1998
Interaction between the carboxyl-terminal heparin-binding domain of fibronectin and (-)-epigallocatechin gallate. Bioscience, biotechnology, and biochemistry, 1998, Volume: 62, Issue:5 Topics: Antineoplastic Agents; Catechin; Cell Adhesion; Fibronectins; Humans; Lung Neoplasms	1998
Synergistic effects of (--)-epigallocatechin gallate with (--)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9. Cancer research, 1999, Jan-01, Volume: 59, Issue:1 Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lung Neoplasms; Mice; Sulindac; Tamoxifen; Tea; Tumor Cells, Cultured	1999
(-)-Epigallocatechin gallate can prevent cisplatin-induced lung tumorigenesis in A/J mice. Carcinogenesis, 2000, Volume: 21, Issue:5 Topics: Animals; Anticarcinogenic Agents; Catechin; Cisplatin; Female; Lung Neoplasms; Mice	2000
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential. International journal of cancer, 2000, Aug-15, Volume: 87, Issue:4 Topics: Animals; Anticarcinogenic Agents; Apigenin; Catechin; Cell Division; Curcumin; Female; Flavonoids; Growth Inhibitors; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Transplantation; Quercetin; Resveratrol; Stilbenes; Tamoxifen; Tumor Cells, Cultured	2000
Modulation of gene expression by (-)-epigallocatechin gallate in PC-9 cells using a cDNA expression array. Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:8 Topics: Antimutagenic Agents; Catechin; DNA Probes; DNA, Complementary; Down-Regulation; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; NF-kappa B; Oligonucleotide Array Sequence Analysis; Poly A; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Up-Regulation	2001
Inhibition of melanoma growth and metastasis by combination with (-)-epigallocatechin-3-gallate and dacarbazine in mice. Journal of cellular biochemistry, 2001, Volume: 83, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Catechin; Cell Aggregation; Cell Communication; Cell Movement; Cell Transformation, Neoplastic; Dacarbazine; Drug Screening Assays, Antitumor; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Growth Inhibitors; Injections, Intraperitoneal; Lung Neoplasms; Male; Matrix Metalloproteinases; Melanoma, Experimental; Mice; Neoplasm Transplantation; Phosphorylation; Protein-Tyrosine Kinases; Survival Rate; Tea; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine	2001
Lung cancer prevention with (-)-epigallocatechin gallate using monitoring by heterogeneous nuclear ribonucleoprotein B1. International journal of oncology, 2002, Volume: 20, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Catechin; Cell Cycle; Gene Expression Regulation; Genistein; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Lung Neoplasms; Ribonucleoproteins; RNA, Messenger; Tea; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2002
Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants. Cancer research, 1992, Jul-15, Volume: 52, Issue:14 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Caffeine; Carcinogens; Catechin; Deoxyguanosine; DNA; Female; Guanine; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Tea	1992