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epigallocatechin gallate and Diabetes Mellitus, Adult-Onset

epigallocatechin gallate has been researched along with Diabetes Mellitus, Adult-Onset in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (8.33)29.6817
2010's20 (55.56)24.3611
2020's13 (36.11)2.80

Authors

AuthorsStudies
Guo, CL; Guo, SJ; Jiang, B; Li, N; Li, XQ; Shi, DY; Wang, LJ1
Chen, J; Jia, Q; Mehmood, S; Yang, R; Yang, X1
Ghosh, D; Jagdale, P; Kar, AK; Patnaik, S; Saji, J; Shraogi, N; Singh, A; Singh, D; Verma, R1
Jia, Q; Li, Y; Mehmood, S; Yang, R1
Jiang, Y; Liu, Y; Xu, H; Yu, H; Zhu, M1
James, A; Wang, K; Wang, Y1
Bao, J; Chen, F; Chen, J; Gan, W; Ren, K; Wang, M; Wang, T; Yu, P; Zhang, F; Zhang, Z1
Jin, L; Liang, G; Lv, Y; Wang, Y1
Lu, Y; Ren, Z; Yang, H; Yang, Z; Zhang, R1
Huang, YW; Pang, QQ; Sheng, J; Wang, XJ; Yang, XY; Yu, CJ; Zhang, XJ; Zhu, QQ1
Hou, G; Liu, H; Liu, Q; Xi, X1
Diao, Y; Hu, X; Li, L; Li, X; Liu, H; Peng, J; Xu, Q; Yin, H; Yu, J; Zhang, C; Zhang, X; Zhang, Y1
Wang, J; Wang, Z; Xin, C; Zhao, M1
Alipour, M; Allivand, M; Bazyar, H; Hosseini, SA; Labibzadeh, M; Mombaini, D; Saradar, S1
Guan, Y; Li, Y; Ling, F; Niu, Y; Wu, Y; Yuan, H; Zhang, C; Zhang, Q1
Chen, M; Li, S; Li, X; Sun, Z; Wang, J; Xie, B1
Casanova, E; Crescenti, A; Gibert-Ramos, A; Salvadó, J1
Ahn, S; Bae, JH; Bae, KC; Cho, HC; Choi, YJ; Im, SS; Kim, SP; Kim, YW; Park, JH; Song, DK1
Chan, KC; Chang, YH; Chao, YC; Huang, SM; Lai, CY; Lin, JA; Tseng, ST; Wu, CH; Yen, GC1
Kim, JJ; Qu, X; Sun, YL; Tan, Y; Xiao, L1
Goda, T; Mochizuki, K; Suzuki, T; Uchiyama, Y2
Gu, D; Hu, G; Jiao, H; Ni, X1
Keske, MA; Kim, JA; Munir, K; Ng, HL; Premilovac, D; Quon, MJ; Rattigan, S; Yang, P1
Huang, J; Wang, Y; Yang, CS; Zhang, J; Zhang, L1
Brender, JR; Fierke, CA; Pithadia, A; Ramamoorthy, A1
Ishizaki, Y; Kikuzaki, H; Kobayashi, K; Kojo, S1
Botelho, PB; de Morais, AC; Ferreira, MA; Mota, JF; Silva, DM1
Chen, CH; He, YM; Li, ZH; Ma, GL; Xu, LH; Xu, ZX; Yang, HJ; Zhang, Q; Zhang, Y; Zhou, GR; Zhou, P1
Cai, EP; Lin, JK1
Abedini, A; Meng, F; Plesner, A; Raleigh, DP; Verchere, CB1
Chou, P; Hsu, CH; Huang, CJ; Liao, YL; Lin, SC; Tsai, TH1
Feng, Z; Liu, J; Long, J; Shen, W; Wang, Y; Weber, P; Wertz, K; Yan, J1
Gradinaru, D; Ilie, M; Margina, D1
Preller, M; Raederstorff, D; Riegger, C; Teixeira, SR; Wang, Y; Weber, P; Wolfram, S1
Goda, T; Mochizuki, K; Sakurai, N; Shimada, M1

Reviews

8 review(s) available for epigallocatechin gallate and Diabetes Mellitus, Adult-Onset

ArticleYear
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Structure-Activity Relationship

2018
Therapeutic Activity of Green Tea Epigallocatechin-3-Gallate on Metabolic Diseases and Non-Alcoholic Fatty Liver Diseases: The Current Updates.
    Nutrients, 2023, Jul-03, Volume: 15, Issue:13

    Topics: Antioxidants; Catechin; Diabetes Mellitus, Type 2; Humans; Metabolic Diseases; Non-alcoholic Fatty Liver Disease; Obesity; Polyphenols; Tea

2023
Epigallocatechin Gallate Modulates Muscle Homeostasis in Type 2 Diabetes and Obesity by Targeting Energetic and Redox Pathways: A Narrative Review.
    International journal of molecular sciences, 2019, Jan-27, Volume: 20, Issue:3

    Topics: Animals; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Metabolism; Epigenesis, Genetic; Glucose; Homeostasis; Humans; Lipid Metabolism; Muscle, Skeletal; NF-kappa B; Obesity; Oxidative Stress; Signal Transduction

2019
Having a promising efficacy on type II diabetes, it's definitely a green tea time.
    Current medicinal chemistry, 2015, Volume: 22, Issue:1

    Topics: Animals; Antioxidants; Catechin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin; Polyphenols; Polysaccharides; Signal Transduction; Tea

2015
Vascular and metabolic actions of the green tea polyphenol epigallocatechin gallate.
    Current medicinal chemistry, 2015, Volume: 22, Issue:1

    Topics: Adipose Tissue; Animals; Cardiovascular Diseases; Catechin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Liver; Muscle, Skeletal; Nitric Oxide; Tea

2015
Mechanisms of body weight reduction and metabolic syndrome alleviation by tea.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:1

    Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Camellia sinensis; Cardiovascular Diseases; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Liver; Meta-Analysis as Topic; Metabolic Syndrome; Muscle, Skeletal; Plant Leaves; Polyphenols; Randomized Controlled Trials as Topic; Risk Factors; Tea; Weight Loss

2016
Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Catechin; Curcumin; Diabetes Mellitus, Type 2; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Resveratrol; Stilbenes

2016
Therapeutic potential of green tea on risk factors for type 2 diabetes in obese adults - a review.
    Obesity reviews : an official journal of the International Association for the Study of Obesity, 2016, Volume: 17, Issue:12

    Topics: Animals; Antioxidants; Body Composition; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Inflammation; Insulin Resistance; Meta-Analysis as Topic; Obesity; Oxidative Stress; Phytotherapy; Randomized Controlled Trials as Topic; Risk Factors; Tea

2016

Trials

3 trial(s) available for epigallocatechin gallate and Diabetes Mellitus, Adult-Onset

ArticleYear
Effects of epigallocatechin-3-gallate of
    Journal of complementary & integrative medicine, 2020, Dec-25, Volume: 18, Issue:2

    Topics: Antioxidants; Biomarkers; Blood Pressure; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Flour; Humans; Lipids; Plant Leaves; Triticum

2020
EGCG-rich green tea extract stimulates sRAGE secretion to inhibit S100A12-RAGE axis through ADAM10-mediated ectodomain shedding of extracellular RAGE in type 2 diabetes.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:12

    Topics: ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Female; Humans; Male; Membrane Proteins; Middle Aged; Monocytes; Plant Extracts; Protein Structure, Tertiary; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Proteins; S100A12 Protein

2013
Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial.
    Alternative medicine review : a journal of clinical therapeutic, 2011, Volume: 16, Issue:2

    Topics: Adult; Antioxidants; Body Mass Index; Catechin; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Obesity; Prospective Studies; Tea; Treatment Outcome; Waist-Hip Ratio; Weight Loss; Young Adult

2011

Other Studies

25 other study(ies) available for epigallocatechin gallate and Diabetes Mellitus, Adult-Onset

ArticleYear
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats.
    Experimental biology and medicine (Maywood, N.J.), 2022, Volume: 247, Issue:16

    Topics: Animals; Catechin; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Hyperglycemia; Inflammasomes; Inflammation; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Tea

2022
Biopolymeric composite hydrogel loaded with silver NPs and epigallocatechin gallate (EGCG) effectively manages ROS for rapid wound healing in type II diabetic wounds.
    International journal of biological macromolecules, 2022, Oct-01, Volume: 218

    Topics: Animals; Catechin; Diabetes Mellitus, Type 2; Hydrogels; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Silver; Wound Healing

2022
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
    Experimental biology and medicine (Maywood, N.J.), 2022, Volume: 247, Issue:17

    Topics: Adenosine; AMP-Activated Protein Kinases; Animals; Autophagy; Beclin-1; Blood Glucose; Catechin; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Fibrosis; Hydroxyproline; Hypertrophy; Mammals; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microtubule-Associated Proteins; Rats; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1

2022
Epigallocatechin gallate inhibits SNARE-dependent membrane fusion by blocking trans-SNARE assembly.
    FEBS open bio, 2022, Volume: 12, Issue:12

    Topics: Diabetes Mellitus, Type 2; Humans; Insulins; Membrane Fusion; SNARE Proteins

2022
Beneficial effects of green tea on age related diseases.
    Frontiers in bioscience (Scholar edition), 2020, 01-01, Volume: 12, Issue:1

    Topics: Aging; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Functional Food; Humans; Metabolic Syndrome; Obesity; Plant Extracts; Tea

2020
Revealing the Mechanism of EGCG, Genistein, Rutin, Quercetin, and Silibinin Against hIAPP Aggregation via Computational Simulations.
    Interdisciplinary sciences, computational life sciences, 2020, Volume: 12, Issue:1

    Topics: Catechin; Diabetes Mellitus, Type 2; Genistein; Humans; Islet Amyloid Polypeptide; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Quercetin; Rutin; Silybin

2020
Anti‑glycolipid disorder effect of epigallocatechin‑3‑gallate on high‑fat diet and STZ‑induced T2DM in mice.
    Molecular medicine reports, 2020, Volume: 21, Issue:6

    Topics: Animals; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Endothelial Cells; Glycolipids; Hypercholesterolemia; Hyperlipidemias; Insulin Resistance; Lipids; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Sterol Regulatory Element Binding Protein 2; Streptozocin

2020
EGCG targeting Notch to attenuate renal fibrosis
    Food & function, 2020, Nov-18, Volume: 11, Issue:11

    Topics: Animals; Antioxidants; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Injections, Intraperitoneal; Mice; Mice, Inbred ICR; Random Allocation; Renal Insufficiency, Chronic; Signal Transduction; Smad3 Protein; Streptozocin; Transforming Growth Factor beta

2020
[Effects of swimming and epigallocatechin gallate on interstitial proteins expression of myocardium from type 2 diabetic rats].
    Wei sheng yan jiu = Journal of hygiene research, 2021, Volume: 50, Issue:1

    Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Male; Myocardium; Rats; Rats, Sprague-Dawley; Swimming; Transforming Growth Factor beta1

2021
Epigallocatechin-3-gallate prevents inflammation and diabetes -Induced glucose tolerance through inhibition of NLRP3 inflammasome activation.
    International immunopharmacology, 2021, Volume: 93

    Topics: Animals; Anti-Inflammatory Agents; Bone Marrow; Catechin; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glucose Tolerance Test; Humans; Inflammasomes; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis

2021
Hawthorn polyphenols, D-chiro-inositol, and epigallocatechin gallate exert a synergistic hypoglycemic effect.
    Journal of food biochemistry, 2021, Volume: 45, Issue:7

    Topics: Animals; Catechin; Crataegus; Diabetes Mellitus, Type 2; Glycogen Synthase Kinase 3; Hypoglycemic Agents; Inositol; Mice; Phosphatidylinositol 3-Kinases; Polyphenols

2021
Epigallocatechin gallate improves insulin resistance in HepG2 cells through alleviating inflammation and lipotoxicity.
    Diabetes research and clinical practice, 2018, Volume: 142

    Topics: Animals; Catechin; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Hep G2 Cells; Humans; Inflammation; Insulin Resistance; Oxidative Stress; Rats; Transfection

2018
(-)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice.
    Food & function, 2018, Sep-19, Volume: 9, Issue:9

    Topics: alpha-Amylases; alpha-Glucosidases; Animals; Camellia sinensis; Catechin; Constitutive Androstane Receptor; Diabetes Mellitus, Type 2; Gluconeogenesis; Glucose; Homeostasis; Humans; Intestine, Small; Lipogenesis; Liver; Male; Mice; Mice, Inbred ICR; Plant Extracts; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Starch; Sterol Regulatory Element Binding Protein 1

2018
Green tea extract with polyethylene glycol-3350 reduces body weight and improves glucose tolerance in db/db and high-fat diet mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:8

    Topics: Adiponectin; Adipose Tissue; Animals; Anti-Obesity Agents; Caco-2 Cells; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucose; Glucose Intolerance; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Organ Size; Plant Extracts; Polyethylene Glycols; Retinol-Binding Proteins, Plasma

2013
Green tea polyphenol epigallocatechin-3-gallate enhance glycogen synthesis and inhibit lipogenesis in hepatocytes.
    BioMed research international, 2013, Volume: 2013

    Topics: Antioxidants; Catechin; Diabetes Mellitus, Type 2; Glycogen; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Lipogenesis; Metabolic Syndrome; Phosphorylation; Proto-Oncogene Proteins c-akt; Tea

2013
Dietary supplementation with (-)-epigallocatechin-3-gallate reduces inflammatory response in adipose tissue of non-obese type 2 diabetic Goto-Kakizaki (GK) rats.
    Journal of agricultural and food chemistry, 2013, Nov-27, Volume: 61, Issue:47

    Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Type 2; Dietary Supplements; Gene Expression Regulation; Inflammation; Male; Obesity; Oxidative Stress; Rats; Rats, Wistar

2013
Dietary supplementation with a low dose of (-)-epigallocatechin-3-gallate reduces pro-inflammatory responses in peripheral leukocytes of non-obese type 2 diabetic GK rats.
    Journal of nutritional science and vitaminology, 2013, Volume: 59, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Catechin; Chemokines; Corn Oil; Cytokines; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Inflammation; Leukocytes; Male; Malondialdehyde; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Wistar

2013
Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate.
    Journal of nutritional science and vitaminology, 2016, Volume: 62, Issue:2

    Topics: Animals; Atherosclerosis; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Hydrogen-Ion Concentration; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase

2016
Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Aluminum; Amyloid; Catechin; Chelating Agents; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Kinetics; Light; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Scattering, Radiation; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2016
Epigallocatechin gallate (EGCG) and rutin suppress the glucotoxicity through activating IRS2 and AMPK signaling in rat pancreatic beta cells.
    Journal of agricultural and food chemistry, 2009, Oct-28, Volume: 57, Issue:20

    Topics: AMP-Activated Protein Kinases; Animals; Catechin; Cell Line, Tumor; Diabetes Mellitus, Type 2; Down-Regulation; Glucose; Humans; Insulin Receptor Substrate Proteins; Insulin-Secreting Cells; Rats; Rutin; Signal Transduction

2009
The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.
    Biochemistry, 2010, Sep-21, Volume: 49, Issue:37

    Topics: alpha-Synuclein; Amyloid; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Catechin; Cell Culture Techniques; Diabetes Mellitus, Type 2; Flavonoids; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Phenols; Polyphenols; Protease Nexins; Rats; Receptors, Cell Surface; Thiazoles

2010
Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: ameliorating effects of (-)-epigallocatechin-3-gallate.
    The Journal of nutritional biochemistry, 2012, Volume: 23, Issue:7

    Topics: Animals; Autophagy; Blood Glucose; Catechin; Diabetes Mellitus, Type 2; Down-Regulation; Fasting; Hypoglycemic Agents; Insulin Resistance; Male; Mitochondria; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Oxidative Stress; Rats; Tumor Suppressor Protein p53; Up-Regulation

2012
Quercetin and epigallocatechin gallate induce in vitro a dose-dependent stiffening and hyperpolarizing effect on the cell membrane of human mononuclear blood cells.
    International journal of molecular sciences, 2012, Volume: 13, Issue:4

    Topics: Adult; Aged; Anisotropy; Biomarkers; Cardiovascular Diseases; Catechin; Cell Membrane; Cell Polarity; Diabetes Mellitus, Type 2; Diet, Vegetarian; Female; Humans; Hyperglycemia; Inflammation; Insulin; Insulin Resistance; Leukocytes, Mononuclear; Male; Membrane Fluidity; Membrane Potentials; Middle Aged; Quercetin; Resistin

2012
Epigallocatechin gallate supplementation alleviates diabetes in rodents.
    The Journal of nutrition, 2006, Volume: 136, Issue:10

    Topics: Acyl-CoA Oxidase; Adipose Tissue; Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Catechin; Cell Line, Tumor; Diabetes Mellitus, Type 2; Dietary Supplements; Gene Expression; Gene Expression Regulation; Glucokinase; Glucose; Glucose Tolerance Test; Lipid Metabolism; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Sprague-Dawley; RNA, Messenger

2006
Dietary supplementation with epigallocatechin gallate elevates levels of circulating adiponectin in non-obese type-2 diabetic Goto-Kakizaki rats.
    Bioscience, biotechnology, and biochemistry, 2007, Volume: 71, Issue:8

    Topics: Adiponectin; Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Lipid Metabolism; Rats; Rats, Inbred Strains; Triglycerides

2007