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epigallocatechin gallate and Degenerative Diseases, Central Nervous System

epigallocatechin gallate has been researched along with Degenerative Diseases, Central Nervous System in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (21.74)29.6817
2010's13 (56.52)24.3611
2020's5 (21.74)2.80

Authors

AuthorsStudies
Chen, L; Dong, L; Tan, Y; Wang, D; Wang, F; Wang, H; Zhu, W1
Bourgeois, B; Habacher, H; Khanna, Y; Lenard, AJ; Madl, T; Madreiter-Sokolowski, C; Zhou, Q1
Alarcón-Jimenez, J; Cuerda-Ballester, M; de Bernardo, N; de la Rubia Ortí, JE; Lajara Romance, JM; Proaño, B; Villaron-Casales, C1
Sharma, A; Thakur, A; Tuli, HS1
Fukutomi, R; Isemura, M; Koyama, Y; Nakamura, Y; Ohishi, T; Pervin, M1
Cordeiro, Y; Gonçalves, PB; Sodero, ACR1
Airoldi, C; Bonanomi, M; De Gioia, L; Gatta, E; Natalello, A; Pellistri, F; Penco, A; Regonesi, ME; Relini, A; Tortora, P; Vertemara, J; Visentin, C1
Jimenez-Del-Rio, M; Martinez-Perez, DA; Velez-Pardo, C1
Khademi, E; Khalatbary, AR1
Elbaz, HA; Hüttemann, M; Lee, I; Malek, MH; Shay, J; Zielske, SP1
Goto, S; Isemura, M; Monira, P; Nakamura, Y; Ohishi, T1
Amit, T; Kalfon, L; Mandel, SA; Reznichenko, L; Weinreb, O; Youdim, MB1
Kumar, A; Kumar, P1
Emmer, KL; Giasson, BI; Waxman, EA1
Chopra, K; Kuhad, A; Tiwari, V1
Cavalieri, E; Darra, E; Ebner, FH; Mariotto, S; Suzuki, H1
Abraham, NG; Calogero, C; Caruso, C; Fabio, G; Nader, AG; Scapagnini, G; Sonya, V; Vasto, S; Zella, D1
Calabrese, V; Caruso, C; Scapagnini, G1
Gomez-Pinilla, F; Nguyen, TT1
Maag, JL; Musgrave, IF; Smid, SD1
Amit, T; Mandel, S; Weinreb, O; Youdim, MB1
Amit, T; Mandel, S; Reznichenko, L; Weinreb, O; Youdim, MB1
Amit, T; Avramovich-Tirosh, Y; Mandel, S; Youdim, MB1

Reviews

13 review(s) available for epigallocatechin gallate and Degenerative Diseases, Central Nervous System

ArticleYear
Beneficial Effects of Epigallocatechin-3-
    Molecules (Basel, Switzerland), 2021, Jan-14, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Agents; Antioxidants; Catechin; Chlorogenic Acid; Curcumin; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Resveratrol

2021
Green Tea Epigallocatechin-3-gallate (EGCG) Targeting Protein Misfolding in Drug Discovery for Neurodegenerative Diseases.
    Biomolecules, 2021, 05-20, Volume: 11, Issue:5

    Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Protein Precursor; Catechin; Drug Discovery; Humans; Molecular Targeted Therapy; Neurodegenerative Diseases; Parkinson Disease; Protein Aggregates; Protein Folding; Tea

2021
The green tea polyphenolic catechin epigallocatechin gallate and neuroprotection.
    Nutritional neuroscience, 2020, Volume: 23, Issue:4

    Topics: Animals; Apoptosis; Brain; Brain Injuries; Catechin; Clinical Trials as Topic; Humans; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Plant Extracts; Spinal Cord Injuries; Tea

2020
Molecular Mechanisms and Therapeutic Effects of (-)-Epicatechin and Other Polyphenols in Cancer, Inflammation, Diabetes, and Neurodegeneration.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Catechin; Humans; Inflammation; Mitochondria; Neoplasms; Neurodegenerative Diseases; Polyphenols; Reactive Oxygen Species; Signal Transduction

2015
Anti-inflammatory Action of Green Tea.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2016, Volume: 15, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Camellia sinensis; Cardiovascular Diseases; Catechin; Diabetes Mellitus; Humans; Inflammation Mediators; Neoplasms; Neurodegenerative Diseases; Obesity; Reactive Oxygen Species; Tea

2016
Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate (EGCG).
    Journal of Alzheimer's disease : JAD, 2008, Volume: 15, Issue:2

    Topics: Alzheimer Disease; Catechin; Flavonoids; Humans; Iron Chelating Agents; Neurodegenerative Diseases; Nootropic Agents; Phenols; Polyphenols; Signal Transduction; Tea

2008
Use of STAT1 inhibitors in the treatment of brain I/R injury and neurodegenerative diseases.
    Central nervous system agents in medicinal chemistry, 2011, Mar-01, Volume: 11, Issue:1

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Catechin; Humans; Janus Kinases; Molecular Structure; Neurodegenerative Diseases; Neuroprotective Agents; Phloroglucinol; Reperfusion Injury; Signal Transduction; STAT1 Transcription Factor; Terpenes

2011
Modulation of Nrf2/ARE pathway by food polyphenols: a nutritional neuroprotective strategy for cognitive and neurodegenerative disorders.
    Molecular neurobiology, 2011, Volume: 44, Issue:2

    Topics: Animals; Antioxidants; Catechin; Cognition Disorders; Curcumin; Diet; Food; Heme Oxygenase-1; Humans; Molecular Structure; Neurodegenerative Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Polyphenols; Response Elements

2011
Natural mood foods: the actions of polyphenols against psychiatric and cognitive disorders.
    Nutritional neuroscience, 2012, Volume: 15, Issue:3

    Topics: Affect; Animals; Antioxidants; Brain; Catechin; Cognition Disorders; Curcumin; Diet; Energy Intake; Energy Metabolism; Food Preferences; Humans; Nervous System Physiological Phenomena; Neurodegenerative Diseases; Oxidative Stress; Polyphenols

2012
Dietary polyphenol-derived protection against neurotoxic β-amyloid protein: from molecular to clinical.
    Food & function, 2012, Volume: 3, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Catechin; Cell Line; Curcumin; Diet; Humans; Models, Molecular; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Plants; Polyphenols; Resveratrol; Stilbenes; Tea

2012
Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases.
    Journal of neurochemistry, 2004, Volume: 88, Issue:6

    Topics: Animals; Catechin; Flavonoids; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Phenols; Polyphenols; Signal Transduction; Tea

2004
Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders.
    Molecular nutrition & food research, 2006, Volume: 50, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain; Catechin; Cell Death; Gene Expression; Humans; Hypoxia; Iron; Iron Chelating Agents; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Tea

2006
Targeting multiple Alzheimer's disease etiologies with multimodal neuroprotective and neurorestorative iron chelators.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Catechin; Cell Cycle; Humans; Hydroxyquinolines; Iron; Iron Chelating Agents; Neurodegenerative Diseases; Neuroprotective Agents; PC12 Cells; Piperazines; Rats

2008

Trials

1 trial(s) available for epigallocatechin gallate and Degenerative Diseases, Central Nervous System

ArticleYear
Improvements in gait and balance in patients with multiple sclerosis after treatment with coconut oil and epigallocatechin gallate. A pilot study.
    Food & function, 2023, Jan-23, Volume: 14, Issue:2

    Topics: Coconut Oil; Gait; Humans; Multiple Sclerosis; Neurodegenerative Diseases; Pilot Projects

2023

Other Studies

9 other study(ies) available for epigallocatechin gallate and Degenerative Diseases, Central Nervous System

ArticleYear
Discovery of potent small molecule inhibitors of DYRK1A by structure-based virtual screening and bioassay.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Adenosine Triphosphate; Animals; Biochemistry; Biological Assay; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Down Syndrome; Drug Design; Dyrk Kinases; Humans; In Vitro Techniques; Inhibitory Concentration 50; Mice; Mice, Transgenic; Models, Chemical; Neurodegenerative Diseases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases

2012
EGCG Promotes FUS Condensate Formation in a Methylation-Dependent Manner.
    Cells, 2022, 02-09, Volume: 11, Issue:4

    Topics: Arginine; Catechin; Glycine; Humans; Methylation; Neurodegenerative Diseases; Proteins; RNA-Binding Protein FUS

2022
Natural Moieties as Anti-Inflammatory Agents-Recent Patents.
    Recent patents on inflammation & allergy drug discovery, 2019, Volume: 13, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Apigenin; Biological Products; Cardiovascular Diseases; Catechin; Coumaric Acids; Humans; Inflammation; Neoplasms; Neurodegenerative Diseases; Patents as Topic; Plants; Polyphenols; Quercetin

2019
Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model.
    Human molecular genetics, 2017, 09-01, Volume: 26, Issue:17

    Topics: Amyloid; Amyloidogenic Proteins; Animals; Ataxin-3; Caenorhabditis elegans; Catechin; Disease Models, Animal; Humans; Hydrogen Bonding; Molecular Docking Simulation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Nuclear Proteins; Peptides; Phenols

2017
Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster.
    Neurotoxicity research, 2018, Volume: 34, Issue:3

    Topics: Animals; Animals, Genetically Modified; Antioxidants; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila melanogaster; Drosophila Proteins; Female; Herbicides; Lipid Peroxidation; Locomotion; Male; Minocycline; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Paraquat; Protein Deglycase DJ-1; Tyrosine 3-Monooxygenase

2018
Protective effects of epigallocatechin gallate following 3-nitropropionic acid-induced brain damage: possible nitric oxide mechanisms.
    Psychopharmacology, 2009, Volume: 207, Issue:2

    Topics: Animals; Antioxidants; Behavior, Animal; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mitochondria; Motor Activity; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Nitric Oxide; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar

2009
Residue Glu83 plays a major role in negatively regulating alpha-synuclein amyloid formation.
    Biochemical and biophysical research communications, 2010, Jan-15, Volume: 391, Issue:3

    Topics: alpha-Synuclein; Amyloid; Catechin; Dopamine; Flavanones; Glutamic Acid; Humans; Mutation; Neurodegenerative Diseases; Neuroprotective Agents

2010
Epigallocatechin-3-gallate ameliorates alcohol-induced cognitive dysfunctions and apoptotic neurodegeneration in the developing rat brain.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:8

    Topics: Animals; Animals, Newborn; Apoptosis; Brain; Catechin; Cognition Disorders; Ethanol; Male; Maze Learning; Neurodegenerative Diseases; Random Allocation; Rats; Rats, Wistar

2010
Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.
    Advances in experimental medicine and biology, 2010, Volume: 698

    Topics: Aging; Antioxidants; Brain; Caffeic Acids; Catechin; Curcumin; Diet; Flavonoids; Neurodegenerative Diseases; Neuroprotective Agents; Phenols; Phenylethyl Alcohol; Polyphenols

2010