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epigallocatechin gallate and Colorectal Neoplasms

epigallocatechin gallate has been researched along with Colorectal Neoplasms in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.94)18.2507
2000's7 (20.59)29.6817
2010's20 (58.82)24.3611
2020's6 (17.65)2.80

Authors

AuthorsStudies
Furukawa, K; Kan, H; Onda, M; Tanaka, N1
Al-Enazy, A; Al-Ghamdi, MA; Albukhari, A; Harakeh, S; Huwait, EA; Moselhy, SS1
Chen, S; Kashihara, H; Morine, Y; Nishi, M; Shimada, M; Takasu, C; Tokunaga, T; Wada, Y; Yamada, S1
Khiewkamrop, P; Parhira, S; Pekthong, D; Richert, L; Somran, J; Srikummool, M; Srisawang, P; Surangkul, D1
Oteiza, PI; Zhu, W1
Chen, H; Fang, MZ; Huang, SL; Jin, HY; Kong, DS; Li, M; Sun, Y; Wang, SM; Wang, XF; Wang, Y; Zhang, X1
Chen, D; Chen, L; Dong, J; Geng, R; Gou, H; Liu, J; Ren, S; Wu, W; Xiang, B; Yang, X; Zhang, Z1
Ohnishi, M; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T1
Chen, Y; Geng, SS; Han, HY; Li, XT; Li, Y; Wang, XQ; Wu, JS; Xie, CF; Zhang, Q; Zhong, CY; Zhu, JY1
Dai, J; Hu, Y; Li, X; Wang, Y; Williams, BR; Xu, D; Xu, P; Yan, F; Ying, L; Zhao, Y1
Cai, YK; Chen, J; Chen, WJ; Hao, Z; Lv, Y; Wang, HP; Wang, X; Ye, T; Zhao, JY1
Enkhbat, T; Ishikawa, D; Jun, H; Kashihara, H; Nishi, M; Shimada, M; Takasu, C; Tokunaga, T; Tominaga, M; Yoshikawa, K1
Chen, BC; Ding, YP; Gao, ZL; Rakariyatham, K; Suo, HY; Tong, HR; Xiao, H1
La, X; Li, H; Li, Z; Yang, Y; Zhang, L1
Fukunaga, K; Maruyama, T; Murata, S; Nakayama, K; Nowatari, T; Nozaki, R; Ogawa, K; Ohkohchi, N; Sano, N; Tamura, T1
Bazzoli, F; Belluzzi, A; Bianchi, F; D'Angelo, L; Fazio, C; Fogliano, V; Graziani, G; Montanaro, L; Munarini, A; Pacilli, A; Piazzi, G; Prossomariti, A; Ricciardiello, L1
Fang, Y; Hu, F; Wang, Y; Wei, F; Wu, B; Xiong, B1
Goel, A; Okugawa, Y; Toden, S; Tovar-Camargo, OA; Tran, HM1
Baek, SJ; Eling, TE; Hara, Y; Lee, SH; McEntee, MF; Sukhthankar, M; Yamaguchi, K1
Baek, SJ; Choi, CK; English, A; Kim, JS; Sukhthankar, M1
Adachi, S; Hara, Y; Kubota, M; Moriwaki, H; Sakai, H; Shimizu, M; Shirakami, Y; Tsurumi, H; Yasuda, Y1
Alberti, S; Baek, SJ; Sukhthankar, M1
Araújo, JR; Gonçalves, P; Martel, F1
Jin, HY; Wang, SM; Zhang, CX1
Gardner, TR; Grieco, M; Herath, SA; Jang, JH; Kirchoff, D; Naffouje, S; Njoh, L; Shantha Kumara, HM; Whelan, RL; Yan, X1
Calway, T; Du, GJ; Du, W; He, TC; Qi, LW; Wang, CZ; Yuan, CS; Zhang, ZY1
Baek, SJ; Min, KW; Wimalasena, J; Zhang, X1
Calway, T; Du, GJ; Wang, CZ; Wen, XD; Yu, C; Yuan, CS; Zhang, Z1
Hamada, H; Iigo, M; Kojima, S; Nomoto, H; Tsuda, H1
Kawabata, K; Kim, M; Murakami, A; Ohigashi, H1
Al-Fageeh, M; Carter, O; Dashwood, RH; Dashwood, WM; Li, Q1
Chuang, JC; Jones, PA; Kwan, JM; Li, TW; Liang, G; Yang, AS; Yoo, CB1
Kim, M; Murakami, A; Ohigashi, H1
Edler, L; Groh, B; Hoensch, H; Kirch, W1

Reviews

2 review(s) available for epigallocatechin gallate and Colorectal Neoplasms

ArticleYear
Prevention of Colorectal Cancer by Targeting Obesity-Related Disorders and Inflammation.
    International journal of molecular sciences, 2017, Apr-26, Volume: 18, Issue:5

    Topics: Animals; Catechin; Colorectal Neoplasms; Humans; Inflammation; Obesity; Phytochemicals; Receptor Protein-Tyrosine Kinases; Tea

2017
Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines.
    Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Diet; Flavonoids; Fruit; Humans; Phenols; Polyphenols; Propiophenones; Quercetin; Resveratrol; Rutin; Stilbenes; Vegetables

2011

Trials

1 trial(s) available for epigallocatechin gallate and Colorectal Neoplasms

ArticleYear
Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence.
    World journal of gastroenterology, 2008, Apr-14, Volume: 14, Issue:14

    Topics: Aged; Aged, 80 and over; Apigenin; Catechin; Cohort Studies; Colon; Colorectal Neoplasms; Female; Flavonoids; Humans; Male; Middle Aged; Prospective Studies; Recurrence; Surveys and Questionnaires

2008

Other Studies

31 other study(ies) available for epigallocatechin gallate and Colorectal Neoplasms

ArticleYear
[Effect of green tea polyphenol fraction on 1,2-dimethylhydrazine (DMH)-induced colorectal carcinogenesis in the rat].
    Nihon Ika Daigaku zasshi, 1996, Volume: 63, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Colorectal Neoplasms; Dimethylhydrazines; Phenols; Plant Extracts; Rats; Rats, Wistar; Tea

1996
Enhancement of Annexin V in response to combination of epigallocatechin gallate and quercetin as a potent arrest the cell cycle of colorectal cancer.
    Brazilian journal of biology = Revista brasleira de biologia, 2021, Volume: 83

    Topics: Annexin A5; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Quercetin

2021
Epigallocatechin‑3‑gallate hinders metabolic coupling to suppress colorectal cancer malignancy through targeting aerobic glycolysis in cancer‑associated fibroblasts.
    International journal of oncology, 2022, Volume: 60, Issue:2

    Topics: Cancer-Associated Fibroblasts; Catechin; Colorectal Neoplasms; Humans; Neoplasms; Oxidative Coupling; Warburg Effect, Oncologic

2022
Epigallocatechin gallate triggers apoptosis by suppressing de novo lipogenesis in colorectal carcinoma cells.
    FEBS open bio, 2022, Volume: 12, Issue:5

    Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Fatty Acids; Humans; Lipogenesis; Mice

2022
NADPH oxidase 1: A target in the capacity of dimeric ECG and EGCG procyanidins to inhibit colorectal cancer cell invasion.
    Redox biology, 2023, Volume: 65

    Topics: Caco-2 Cells; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Electrocardiography; Epidermal Growth Factor; ErbB Receptors; Humans; Matrix Metalloproteinase 2; NADPH Oxidase 1; Neoplasm Invasiveness; Proanthocyanidins

2023
Epigallocatechin gallate inhibits dimethylhydrazine-induced colorectal cancer in rats.
    World journal of gastroenterology, 2020, May-07, Volume: 26, Issue:17

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Carcinogenesis; Catechin; Cell Proliferation; Colon; Colorectal Neoplasms; Dimethylhydrazines; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Intestinal Mucosa; Male; Neoplasms, Experimental; Protein Interaction Maps; Rats; Rectum; Signal Transduction

2020
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:16

    Topics: Antioxidants; Autophagy; Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; DNA Damage; Drug Synergism; Drug Therapy, Combination; Humans; Irinotecan; Topoisomerase I Inhibitors

2021
(-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway.
    Nutrients, 2017, Jun-03, Volume: 9, Issue:6

    Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Neoplastic Stem Cells; Tea; Wnt Signaling Pathway

2017
(-)-Epigallocatechin-3-gallate and EZH2 inhibitor GSK343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells.
    Clinical and experimental pharmacology & physiology, 2018, Volume: 45, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Enhancer of Zeste Homolog 2 Protein; Humans; Indazoles; Neoplasm Invasiveness; Pyridones

2018
Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice.
    World journal of gastroenterology, 2017, Dec-14, Volume: 23, Issue:46

    Topics: Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogenesis; Carcinogens; Catechin; Colon; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Mice; Rectum; RNA, Ribosomal, 16S

2017
Epigallocatechin-3-gallate Enhances Radiation Sensitivity in Colorectal Cancer Cells Through Nrf2 Activation and Autophagy.
    Anticancer research, 2018, Volume: 38, Issue:11

    Topics: Caspase 9; Catechin; Cell Nucleus; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Microtubule-Associated Proteins; NF-E2-Related Factor 2; Protein Transport; Radiation-Sensitizing Agents; Transcriptional Activation

2018
The Effect of Different Treatments of (-)-Epigallocatechin-3-Gallate on Colorectal Carcinoma Cell Lines.
    Nutrition and cancer, 2018, Volume: 70, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Catechin; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Drug Stability; HCT116 Cells; Humans; Proteins

2018
(-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway.
    Journal of agricultural and food chemistry, 2019, Mar-06, Volume: 67, Issue:9

    Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Catechin; Colorectal Neoplasms; DNA Damage; Drug Interactions; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Fluorouracil; Gene Expression; HCT116 Cells; Heat-Shock Proteins; Humans; MicroRNAs; NF-kappa B; Signal Transduction

2019
(-)-Epigallocatechin-3-gallate suppresses liver metastasis of human colorectal cancer.
    Oncology reports, 2014, Volume: 31, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Enzyme Activation; HCT116 Cells; Humans; Liver Neoplasms; Male; Mice; Mice, SCID; Neovascularization, Pathologic; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor Receptor-2

2014
A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells.
    Carcinogenesis, 2014, Volume: 35, Issue:10

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Eicosapentaenoic Acid; Grape Seed Extract; Humans; Proanthocyanidins; Proto-Oncogene Proteins c-myc; Signal Transduction; TOR Serine-Threonine Kinases

2014
EGCG synergizes the therapeutic effect of cisplatin and oxaliplatin through autophagic pathway in human colorectal cancer cells.
    Journal of pharmacological sciences, 2015, Volume: 128, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Autophagy; Catechin; Cell Transformation, Neoplastic; Cisplatin; Colorectal Neoplasms; Drug Synergism; HT29 Cells; Humans; Microtubule-Associated Proteins; Organoplatinum Compounds; Oxaliplatin; Signal Transduction; Tea; Tumor Cells, Cultured

2015
Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer.
    Oncotarget, 2016, Mar-29, Volume: 7, Issue:13

    Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Humans; Mice; Mice, Nude; Neoplastic Stem Cells

2016
A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Acetylcysteine; Adenomatous Polyposis Coli; Animals; Antineoplastic Agents, Phytogenic; Camellia sinensis; Catechin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cycloheximide; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Time Factors; Transfection

2008
A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level.
    The Journal of nutritional biochemistry, 2010, Volume: 21, Issue:2

    Topics: 3' Untranslated Regions; Anticarcinogenic Agents; Catechin; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Half-Life; Humans; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Tea; Time Factors

2010
(-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells.
    Chemico-biological interactions, 2010, May-14, Volume: 185, Issue:3

    Topics: Anticarcinogenic Agents; Caco-2 Cells; Catechin; Cell Line, Tumor; Colorectal Neoplasms; ErbB Receptors; HCT116 Cells; HT29 Cells; Humans; Vascular Endothelial Growth Factor A

2010
(-)-Epigallocatechin-3-gallate (EGCG) post-transcriptionally and post-translationally suppresses the cell proliferative protein TROP2 in human colorectal cancer cells.
    Anticancer research, 2010, Volume: 30, Issue:7

    Topics: Anticarcinogenic Agents; Antigens, Neoplasm; Antioxidants; Catechin; Cell Adhesion Molecules; Colorectal Neoplasms; Dose-Response Relationship, Drug; HCT116 Cells; HT29 Cells; Humans; Protein Biosynthesis; Protein Processing, Post-Translational; RNA, Messenger

2010
[Inhibitory effect and mechanism of (-)-epigallocatechin-3-gallate on HT29 and HCT-8 colorectal cancer cell lines and expression of HES1 and JAG1].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2011, Volume: 14, Issue:8

    Topics: Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Calcium-Binding Proteins; Catechin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Flow Cytometry; Homeodomain Proteins; HT29 Cells; Humans; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Membrane Proteins; Serrate-Jagged Proteins; Transcription Factor HES-1

2011
Perioperative polyphenon E- and siliphos-inhibited colorectal tumor growth and metastases without impairment of gastric or abdominal wound healing in mouse models.
    Surgical endoscopy, 2012, Volume: 26, Issue:7

    Topics: Abdomen; Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Collagen; Colorectal Neoplasms; Drug Combinations; Female; Laparotomy; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Transplantation; Perioperative Period; Pneumoperitoneum, Artificial; Pressure; Random Allocation; Silybin; Silymarin; Stomach; Surgical Wound Dehiscence; Wound Healing

2012
The synergistic apoptotic interaction of panaxadiol and epigallocatechin gallate in human colorectal cancer cells.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:2

    Topics: Annexin A5; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Synergism; Ginsenosides; Humans; Molecular Docking Simulation

2013
Cyclin D1 degradation and p21 induction contribute to growth inhibition of colorectal cancer cells induced by epigallocatechin-3-gallate.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:12

    Topics: Apoptosis; Caco-2 Cells; Caspase 3; Caspase 7; Catechin; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; HCT116 Cells; HT29 Cells; Humans; MAP Kinase Signaling System; NF-kappaB-Inducing Kinase; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteolysis; Signal Transduction; Ubiquitination; Up-Regulation

2012
Epigallocatechin Gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea.
    Nutrients, 2012, Nov-08, Volume: 4, Issue:11

    Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; HCT116 Cells; Humans; Models, Molecular; Molecular Structure; Polyphenols; Structure-Activity Relationship; Tea

2012
Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis.
    Nutrition and cancer, 2004, Volume: 49, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Azoxymethane; Biflavonoids; Carcinogens; Caspase 3; Caspases; Catechin; Cell Division; Colorectal Neoplasms; Immunohistochemistry; Male; Proanthocyanidins; Random Allocation; Rats; Rats, Inbred F344

2004
(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
    Carcinogenesis, 2005, Volume: 26, Issue:9

    Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Enzyme Activation; Enzyme Precursors; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 7; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; p38 Mitogen-Activated Protein Kinases

2005
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
    Mutation research, 2005, Dec-11, Volume: 591, Issue:1-2

    Topics: Anticarcinogenic Agents; beta Catenin; Cadherins; Catechin; Cell Line; Colonic Neoplasms; Colorectal Neoplasms; Genes, Reporter; Humans; Lysosomes; Recombinant Fusion Proteins; Signal Transduction; TCF Transcription Factors; Tea; Transcription Factor 7-Like 2 Protein

2005
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:10

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction

2005
Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.
    Bioscience, biotechnology, and biochemistry, 2007, Volume: 71, Issue:10

    Topics: Acetylcysteine; Antioxidants; Catechin; Colorectal Neoplasms; Culture Media; Curcumin; Gallic Acid; Genes, Reporter; HT29 Cells; Humans; Hydrogen Peroxide; Isothiocyanates; Luciferases; Matrix Metalloproteinase 7; RNA, Messenger; Transcription Factor AP-1

2007