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epigallocatechin gallate and Cancer of Mouth

epigallocatechin gallate has been researched along with Cancer of Mouth in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.06)18.2507
2000's9 (27.27)29.6817
2010's18 (54.55)24.3611
2020's4 (12.12)2.80

Authors

AuthorsStudies
Ishikawa, T; Kon, M; Ogasawara, M; Ohashi, Y; Yamada, H1
Bai, J; Cai, X; Jing, F; Li, T; Zhang, H; Zhang, J; Zhou, X; Zhu, L1
Chen, L; Guo, X; Hu, Y; Li, L; Liang, G; Zhang, G1
Chen, HM; Chen, HY; Chiang, CP; Li, WC; Lin, HY; Wei, YC; Yang, H1
López Jornet, P; Pons-Fuster López, E; Wang, QT; Wei, W1
Gómez García, F; López Jornet, P; Pons-Fuster López, E1
Kiyoshima, T; Kobayashi, M; Matsuda, S; Ohmori, M; Ohta, K; Ryoke, T; Sano, K; Yamamoto, S; Yoshida, H; Yoshimura, H1
Chaushu, G; Dayan, A; Dayan, D; Salo, T; Vered, M; Zlotogorski, A1
Chung, WY; Hwang, YS; Park, KK1
Iriti, M; Varoni, EM1
Forester, SC; Lambert, JD; Tao, L1
Lambert, JD; Park, JY; Tao, L1
Chen, WT; Chen, YJ; Chung, LC; Feng, TH; Juang, HH; Lee, JC1
Chen, LL; Geng, Y; Han, WF; Su, JS1
Messadi, DV; Sato, K1
Chen, FA; Chiang, JH; Chiang, NN; Horng, CT; Hsu, YM; Lee, CF; Lu, CC; Tsai, FJ; Yang, JS; Yuan, CH1
Hara, A; Hatakeyama, D; Kato, K; Long, NK; Makita, H; Mori, H; Shibata, T; Toida, M; Yamashita, T1
Chen, YJ; Cheng, CW; Kao, JY; Kao, MC; Kuo, DH; Lin, YC; Lin, YH; Liu, JY; Shieh, PC; Way, TD1
Choi, EC; Hwang, HS; Kang, SU; Kim, CH; Koh, YW; Lee, MH; Lee, Y; Park, R; Pyun, J1
Chen, PN; Chou, MY; Chu, SC; Hsieh, YS; Kuo, WH; Lin, JK1
Aizenbud, D; Levy, Y; Narotzki, B; Reznick, AZ1
Chang, YC; Ho, YC; Lee, SS; Tsai, CH; Yu, CC1
Amagaya, S; Chang, CM; Chang, PY; Chen, MY; Jao, HY; Kuo, SC; Lee, CY; Lu, CC; Tu, MG; Yang, JS1
Chang, KW; Chen, YM; Fann, MJ; Kao, SY; Lin, SC; Liu, CJ; Lu, SY; Wang, CP1
Liu, J; Mei, Y; Wei, D1
Chung, FL; Herzog, CR; Schwartz, J; Yang, YM1
Babich, H; Krupka, ME; Nissim, HA; Zuckerbraun, HL1
Chang, KW; Chiang, WC; Lin, SC; Liu, CJ; Wong, YK1
Chang, KW; Hsu, HC; Ko, SY; Lin, SC; Liu, TY1
Aranbayeva, Z; Dickinson, D; Digumarthi, H; Hsu, S; Lewis, J; Messer, R; Osaki, T; Qin, H; Schuster, GS; Wataha, J; Yamamoto, T1
Chang, YC; Chou, MY; Ho, YC; Peng, CY; Yang, SF1
Chou, TC; Edelstein, D; Khafif, A; Sacks, PG; Schantz, SP1
Chen, L; Lee, MJ; Yang, CS1

Reviews

5 review(s) available for epigallocatechin gallate and Cancer of Mouth

ArticleYear
Nutraceuticals as new treatment approaches for oral cancer: II. Green tea extracts and resveratrol.
    Oral oncology, 2013, Volume: 49, Issue:6

    Topics: Animals; Catechin; Dietary Supplements; Humans; Mice; Mouth Neoplasms; Plant Extracts; Resveratrol; Stilbenes; Tea

2013
Chemopreventive potential of flavonoids in oral squamous cell carcinoma in human studies.
    Nutrients, 2013, Jul-08, Volume: 5, Issue:7

    Topics: Administration, Mucosal; Anticarcinogenic Agents; Catechin; Chemoprevention; Drug Delivery Systems; Flavonoids; Fruit; Humans; Mouth Neoplasms; Nanoparticles; Polyphenols; Randomized Controlled Trials as Topic; Tea

2013
Oral Cancer Chernoprevention: Current Status and Future Direction.
    Journal of the California Dental Association, 2016, Volume: 44, Issue:2

    Topics: Anticarcinogenic Agents; Carcinogenesis; Carotenoids; Catechin; Chemoprevention; Humans; Mouth Neoplasms; Plant Preparations; Precancerous Conditions; Trypsin Inhibitor, Bowman-Birk Soybean; Trypsin Inhibitors

2016
Green tea: a promising natural product in oral health.
    Archives of oral biology, 2012, Volume: 57, Issue:5

    Topics: Antioxidants; Catechin; Cell Transformation, Neoplastic; Dental Caries; Halitosis; Humans; Inflammation; Influenza, Human; Mouth Neoplasms; Oral Health; Oxidative Stress; Polyphenols; Smoking; Tea

2012
Tea and cancer prevention: studies in animals and humans.
    The Journal of nutrition, 2003, Volume: 133, Issue:10

    Topics: Animals; Apoptosis; Caffeine; Catechin; Clinical Trials as Topic; Flavonoids; Humans; Lung Neoplasms; Mice; Mouth Neoplasms; Neoplasms; Phenols; Polyphenols; Rats; Smoking; Tea

2003

Other Studies

28 other study(ies) available for epigallocatechin gallate and Cancer of Mouth

ArticleYear
Epigallocatechin gallate stimulated histamine production and downregulated histamine H1 receptor in oral cancer cell lines expressing histidine decarboxylase.
    Journal of oral biosciences, 2022, Volume: 64, Issue:1

    Topics: Catechin; Cell Line; Histamine; Histidine Decarboxylase; Humans; Mouth Neoplasms; Receptors, Cell Surface; Receptors, Histamine H1

2022
Molecular mechanisms underlying the epigallocatechin-3-gallate-mediated inhibition of oral squamous cell carcinogenesis.
    Archives of oral biology, 2023, Volume: 153

    Topics: Carcinogenesis; Catechin; Cell Line, Tumor; Epithelial Cells; Humans; Mouth Neoplasms; Oral Submucous Fibrosis; Signal Transduction

2023
Epigallocatechin-3-gallate sensitises multidrug-resistant oral carcinoma xenografts to vincristine sulfate.
    FEBS open bio, 2020, Volume: 10, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Catechin; Cell Proliferation; Chick Embryo; Chickens; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Injections, Intraperitoneal; KB Cells; Mice; Mice, Nude; Mouth Neoplasms; Neoplasms, Experimental; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vincristine

2020
Natural Compounds Modulate Drug Transporter Mediated Oral Cancer Treatment.
    Biomolecules, 2020, 09-17, Volume: 10, Issue:9

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Catechin; Cell Line, Tumor; Cell Survival; Curcumin; Gefitinib; Humans; Kaplan-Meier Estimate; Mouth Neoplasms; Neoplasm Proteins; Photochemotherapy; Photosensitizing Agents

2020
Potential chemotherapeutic effects of diosgenin, zoledronic acid and epigallocatechin-3-gallate on PE/CA-PJ15 oral squamous cancer cell line.
    Archives of oral biology, 2017, Volume: 82

    Topics: Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Diosgenin; Diphosphonates; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Imidazoles; Mouth Neoplasms; Zoledronic Acid

2017
Combination of 5-Florouracil and polyphenol EGCG exerts suppressive effects on oral cancer cells exposed to radiation.
    Archives of oral biology, 2019, Volume: 101

    Topics: Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Therapy, Combination; Fluorouracil; Humans; Mouth Neoplasms; Radiation

2019
The therapeutic potential of epigallocatechin‑3‑gallate against human oral squamous cell carcinoma through inhibition of cell proliferation and induction of apoptosis: In vitro and in vivo murine xenograft study.
    Molecular medicine reports, 2019, Volume: 20, Issue:2

    Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Xenograft Model Antitumor Assays

2019
Epigallocatechin-3 gallate inhibits cancer invasion by repressing functional invadopodia formation in oral squamous cell carcinoma.
    European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Catechin; Cell Membrane; Cell Movement; Cell Proliferation; Cortactin; Extracellular Matrix; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinases; Mice; Mice, Inbred BALB C; Mouth Neoplasms; Neoplasm Invasiveness; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); rhoA GTP-Binding Protein; Xenograft Model Antitumor Assays

2013
The role of the mitochondrial oxidative stress in the cytotoxic effects of the green tea catechin, (-)-epigallocatechin-3-gallate, in oral cells.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Mouth Neoplasms; Oxidative Stress; Reactive Oxygen Species; Tea

2014
Differential prooxidative effects of the green tea polyphenol, (-)-epigallocatechin-3-gallate, in normal and oral cancer cells are related to differences in sirtuin 3 signaling.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:2

    Topics: Antioxidants; Catechin; Cell Line, Tumor; ERRalpha Estrogen-Related Receptor; Gene Expression Regulation; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Mitochondria; Mouth Neoplasms; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polyphenols; Reactive Oxygen Species; Receptors, Estrogen; Signal Transduction; Sirtuin 3; Superoxide Dismutase; Tea; Transcription Factors

2015
Upregulation of B-cell translocation gene 2 by epigallocatechin-3-gallate via p38 and ERK signaling blocks cell proliferation in human oral squamous cell carcinoma cells.
    Cancer letters, 2015, May-01, Volume: 360, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Catechin; Cell Growth Processes; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; G1 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Immediate-Early Proteins; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Proteins; Up-Regulation; Xenograft Model Antitumor Assays

2015
A genome-wide study of DNA methylation modified by epigallocatechin-3-gallate in the CAL-27 cell line.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Computational Biology; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Humans; Mouth Neoplasms; Signal Transduction

2015
Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling.
    Environmental toxicology, 2017, Volume: 32, Issue:3

    Topics: Apoptosis; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autophagy; Autophagy-Related Proteins; Caspase 3; Caspase 9; Catechin; Cell Line, Tumor; Cisplatin; Down-Regulation; Humans; Microscopy, Fluorescence; Mouth Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT3 Transcription Factor

2017
Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells.
    British journal of cancer, 2008, Aug-19, Volume: 99, Issue:4

    Topics: Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Movement; DNA Methylation; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Glycoproteins; Mouth Neoplasms; Neoplasm Invasiveness; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Tea

2008
Indoleamine 2,3-dioxygenase, an immunomodulatory protein, is suppressed by (-)-epigallocatechin-3-gallate via blocking of gamma-interferon-induced JAK-PKC-delta-STAT1 signaling in human oral cancer cells.
    Journal of agricultural and food chemistry, 2010, Jan-27, Volume: 58, Issue:2

    Topics: Catechin; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Janus Kinases; Mouth Neoplasms; Protein Kinase C-delta; Signal Transduction; STAT1 Transcription Factor

2010
Green tea (-)-epigallocatechin-3-gallate inhibits HGF-induced progression in oral cavity cancer through suppression of HGF/c-Met.
    The Journal of nutritional biochemistry, 2011, Volume: 22, Issue:11

    Topics: Animals; Catechin; Cell Movement; Cell Proliferation; Chemoprevention; Disease Progression; Female; Hepatocyte Growth Factor; Humans; KB Cells; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mouth Neoplasms; Neoplasm Invasiveness; Proto-Oncogene Proteins c-met; Signal Transduction; Tea

2011
Epigallocatechin-3 gallate inhibits invasion, epithelial-mesenchymal transition, and tumor growth in oral cancer cells.
    Journal of agricultural and food chemistry, 2011, Apr-27, Volume: 59, Issue:8

    Topics: Base Sequence; Carcinoma, Squamous Cell; Catechin; Cell Division; Cell Line, Tumor; DNA Primers; Epithelial-Mesenchymal Transition; Fluorescent Antibody Technique; Humans; Mouth Neoplasms; Neoplasm Invasiveness; Reverse Transcriptase Polymerase Chain Reaction

2011
Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.
    Oral diseases, 2012, Volume: 18, Issue:7

    Topics: Acetylcysteine; Areca; Arecoline; Carcinoma, Squamous Cell; Case-Control Studies; Catechin; Cyclooxygenase 2 Inhibitors; Down-Regulation; Female; Flavonoids; Gene Expression; Gene Expression Regulation, Neoplastic; HSP27 Heat-Shock Proteins; Humans; Imidazoles; Male; Middle Aged; Mouth Neoplasms; Nitrobenzenes; Pyridines; Quercetin; Sulfonamides

2012
Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2
    Oncology reports, 2012, Volume: 28, Issue:5

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mouth Neoplasms; Neoplasm Metastasis; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Wound Healing

2012
Regulation of IGFBP-5 expression during tumourigenesis and differentiation of oral keratinocytes.
    The Journal of pathology, 2002, Volume: 198, Issue:3

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Catechin; Cell Differentiation; Cell Transformation, Neoplastic; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Library; Humans; Insulin-Like Growth Factor Binding Protein 5; Keratinocytes; Male; Middle Aged; Mouth Neoplasms; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Up-Regulation

2002
Quantification of doxorubicin and validation of reversal effect of tea polyphenols on multidrug resistance in human carcinoma cells.
    Biotechnology letters, 2003, Volume: 25, Issue:4

    Topics: Carcinoma, Squamous Cell; Catechin; Cell Division; Cell Survival; Chromatography, High Pressure Liquid; Doxorubicin; Drug Resistance, Multiple; Flavonoids; Humans; Mouth Neoplasms; Phenols; Polymers; Tea; Tumor Cells, Cultured

2003
Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2005, Volume: 19, Issue:2

    Topics: Antioxidants; Apoptosis; Carcinoma, Squamous Cell; Catechin; Cell Survival; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Gingiva; Humans; Mouth Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured

2005
Increase of MMP-13 expression in multi-stage oral carcinogenesis and epigallocatechin-3-gallate suppress MMP-13 expression.
    Oral diseases, 2006, Volume: 12, Issue:1

    Topics: Adult; Aged; Anticarcinogenic Agents; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Collagenases; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2006
The repressive effect of green tea ingredients on amyloid precursor protein (APP) expression in oral carcinoma cells in vitro and in vivo.
    Cancer letters, 2007, Jan-08, Volume: 245, Issue:1-2

    Topics: Amyloid beta-Protein Precursor; Animals; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Phytotherapy; Plant Preparations; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea

2007
EGCG-targeted p57/KIP2 reduces tumorigenicity of oral carcinoma cells: role of c-Jun N-terminal kinase.
    Toxicology and applied pharmacology, 2007, Nov-01, Volume: 224, Issue:3

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Catechin; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p57; Cytochromes c; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Nude; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Transfection; Xenograft Model Antitumor Assays

2007
Epigallocatechin-3-gallate inhibits the invasion of human oral cancer cells and decreases the productions of matrix metalloproteinases and urokinase-plasminogen activator.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2007, Volume: 36, Issue:10

    Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Cell Survival; Epithelial Cells; Humans; Matrix Metalloproteinase Inhibitors; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Plant Extracts; Tea; Urokinase-Type Plasminogen Activator

2007
Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells.
    Carcinogenesis, 1998, Volume: 19, Issue:3

    Topics: Anticarcinogenic Agents; Catechin; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Flow Cytometry; Humans; Mouth Neoplasms; Precancerous Conditions; Tea

1998
Human salivary tea catechin levels and catechin esterase activities: implication in human cancer prevention studies.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:1

    Topics: Absorption; Adult; Anticarcinogenic Agents; Beverages; Capsules; Catechin; Drinking; Esophageal Neoplasms; Esterases; Female; Flavonoids; Free Radical Scavengers; Half-Life; Humans; Male; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Saliva; Tea

1999