Compounds > epigallocatechin gallate
Page last updated: 2024-08-24

epigallocatechin gallate and Cancer of Head

epigallocatechin gallate has been researched along with Cancer of Head in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's3 (16.67)29.6817
2010's12 (66.67)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Jia, L; Li, X; Mei, H; Meng, X; Xing, L; Yu, J; Zhao, H; Zhao, X; Zhu, W1
Amin, ARMR; Chen, ZG; Lamichhane, R; Nannapaneni, S; Shin, DM; Wang, D1
Kang, HJ; Kwon, HW; Lee, SH; Lim, YC; Nam, HJ1
Chen, WT; Chen, YJ; Chung, LC; Feng, TH; Juang, HH; Lee, JC1
Chen, ZG; Haque, A; Khuri, FR; Rahman, MA; Ruhul Amin, AR; Saba, NF; Shin, DM1
Baek, SJ; Kang, SU; Kim, CH; Kim, YE; Kim, YS; Lee, SH; Park, JK; Shin, YS1
Katiyar, SK1
Chen, Z'; Khuri, FR; Lee, JE; Shin, DM; Shin, HJ; Tighiouart, M; Yang, CS; Zhang, H; Zhang, X1
Amin, AR; Chen, ZG; Khuri, FR; Shin, DM1
Amin, AR; Kim, JW; Shin, DM1
Amin, AR; Brandes, JC; Chen, ZG; Khuri, FR; Peng, S; Shin, DM; Shin, HJ; Tighiouart, M; Wang, D; Zhang, H1
Amin, AR; Rahman, MA; Shin, DM1
Chen, SC; Funayama, S; Ho, CT; Hou, SC; Kao, MC; Lin, HY; Way, TD; Yu, CC1
Baumeister, P; Harréus, U; Reiter, M1
Baek, SJ; Kang, SU; Kim, CH; Lee, BS; Lee, SH; Shin, YS1
Cai, GM; Hunag, DH; Liu, Y; Pi, LM; Qiu, YZ; Tian, YQ; Yu, CY; Zhang, X1
Lim, JT; Masuda, M; Suzui, M; Weinstein, IB1

Reviews

3 review(s) available for epigallocatechin gallate and Cancer of Head

ArticleYear
Emerging Phytochemicals for the Prevention and Treatment of Head and Neck Cancer.
    Molecules (Basel, Switzerland), 2016, Nov-24, Volume: 21, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Evaluation, Preclinical; Head and Neck Neoplasms; Humans; Lignans; Magnolia; Polyphenols; Proanthocyanidins; Squamous Cell Carcinoma of Head and Neck; Tea; Vitis

2016
Chemoprevention of head and neck cancer with green tea polyphenols.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:8

    Topics: Animals; Carcinoma, Squamous Cell; Catechin; Chemoprevention; Flavonoids; Head and Neck Neoplasms; Humans; Models, Biological; Phenols; Plant Extracts; Polyphenols; Tea

2010
Chemopreventive potential of natural compounds in head and neck cancer.
    Nutrition and cancer, 2010, Volume: 62, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Curcumin; Cyclooxygenase 2 Inhibitors; ErbB Receptors; Head and Neck Neoplasms; Humans; NF-kappa B; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53

2010

Trials

2 trial(s) available for epigallocatechin gallate and Cancer of Head

ArticleYear
Epigallocatechin-3-gallate mouthwash protects mucosa from radiation-induced mucositis in head and neck cancer patients: a prospective, non-randomised, phase 1 trial.
    Investigational new drugs, 2020, Volume: 38, Issue:4

    Topics: Adult; Aged; Catechin; Chemoradiotherapy; Head and Neck Neoplasms; Humans; Maximum Tolerated Dose; Middle Aged; Mouth Mucosa; Mouthwashes; Mucositis; Prospective Studies; Radiation Injuries; Young Adult

2020
Green tea and leukoplakia. The Indian-US Head and Neck Cancer Cooperative Group.
    American journal of surgery, 1997, Volume: 174, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Catechin; Chemoprevention; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; India; Leukoplakia, Oral; Male; Middle Aged; Patient Compliance; Risk Factors; Tea

1997

Other Studies

13 other study(ies) available for epigallocatechin gallate and Cancer of Head

ArticleYear
Combination of resveratrol and green tea epigallocatechin gallate induces synergistic apoptosis and inhibits tumor growth
    Oncology reports, 2021, Volume: 45, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinogenesis; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Head and Neck Neoplasms; Humans; Mice; Resveratrol; Signal Transduction; Tea; Xenograft Model Antitumor Assays

2021
Epigallocatechin-3-gallate attenuates head and neck cancer stem cell traits through suppression of Notch pathway.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:15

    Topics: Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Multidrug Resistance-Associated Protein 2; Neoplastic Stem Cells; Receptors, Notch; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Transfection; Xenograft Model Antitumor Assays

2013
Upregulation of B-cell translocation gene 2 by epigallocatechin-3-gallate via p38 and ERK signaling blocks cell proliferation in human oral squamous cell carcinoma cells.
    Cancer letters, 2015, May-01, Volume: 360, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Catechin; Cell Growth Processes; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; G1 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Immediate-Early Proteins; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Proteins; Up-Regulation; Xenograft Model Antitumor Assays

2015
Combination of erlotinib and EGCG induces apoptosis of head and neck cancers through posttranscriptional regulation of Bim and Bcl-2.
    Apoptosis : an international journal on programmed cell death, 2015, Volume: 20, Issue:7

    Topics: Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Catechin; Cell Line, Tumor; Cycloheximide; Drug Synergism; Erlotinib Hydrochloride; Extracellular Signal-Regulated MAP Kinases; Head and Neck Neoplasms; Humans; Membrane Proteins; Phosphorylation; Protein Biosynthesis; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; RNA Interference

2015
Anti-cancer effect of (-)-epigallocatechin-3-gallate (EGCG) in head and neck cancer through repression of transactivation and enhanced degradation of β-catenin.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Nov-15, Volume: 23, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Catechin; Cell Line, Tumor; Cell Proliferation; Female; Gene Knockdown Techniques; Genes, p53; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Inbred C3H; Middle Aged; Neoplasm Transplantation; Signal Transduction; Transcriptional Activation; Ubiquitin-Specific Proteases

2016
Synergistic inhibition of head and neck tumor growth by green tea (-)-epigallocatechin-3-gallate and EGFR tyrosine kinase inhibitor.
    International journal of cancer, 2008, Sep-01, Volume: 123, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Cell Proliferation; Disease Progression; Drug Synergism; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Flow Cytometry; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Protein-Tyrosine Kinases; Quinazolines; Transplantation, Heterologous

2008
Synergistic growth inhibition of squamous cell carcinoma of the head and neck by erlotinib and epigallocatechin-3-gallate: the role of p53-dependent inhibition of nuclear factor-kappaB.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Squamous Cell; Catechin; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; NF-kappa B; Protein Kinase Inhibitors; Quinazolines; RNA, Small Interfering; Transcription Factor RelA; Tumor Suppressor Protein p53

2009
Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin: potential role of p53.
    The Journal of biological chemistry, 2010, Nov-05, Volume: 285, Issue:45

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caspase 3; Catechin; Cell Cycle Proteins; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Drug Synergism; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Ki-67 Antigen; Luteolin; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; Phosphorylation; Protein Serine-Threonine Kinases; Protein Stability; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2010
(-)-Epigallocatechin gallate induces Fas/CD95-mediated apoptosis through inhibiting constitutive and IL-6-induced JAK/STAT3 signaling in head and neck squamous cell carcinoma cells.
    Journal of agricultural and food chemistry, 2012, Mar-14, Volume: 60, Issue:10

    Topics: Apoptosis; Carcinoma, Squamous Cell; Catechin; Down-Regulation; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Interleukin-6; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; STAT3 Transcription Factor

2012
Curcumin and other polyphenolic compounds in head and neck cancer chemoprevention.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Antimutagenic Agents; Catechin; Cell Survival; Cells, Cultured; Curcumin; DNA Damage; Head and Neck Neoplasms; Humans; Nicotiana; Polyphenols

2012
Expression of NSAID-activated gene-1 by EGCG in head and neck cancer: involvement of ATM-dependent p53 expression.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:6

    Topics: Anticarcinogenic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Growth Differentiation Factor 15; Head and Neck Neoplasms; Heterografts; Humans; RNA, Small Interfering; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Protein p53

2013
[EGCG regulates TGF-β1-induced epithelial mesenchymal transition in squamous cell carcinoma of head and neck].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2012, Volume: 47, Issue:9

    Topics: Antigens, CD; Cadherins; Carcinoma, Squamous Cell; Catechin; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Head and Neck Neoplasms; Humans; Signal Transduction; Smad7 Protein; Squamous Cell Carcinoma of Head and Neck; Transforming Growth Factor beta1; Vimentin

2012
Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-15, Volume: 9, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Carcinoma; Catechin; Cell Division; Cell Line, Tumor; Cyclin D1; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Genes, Reporter; Head and Neck Neoplasms; Humans; Immunoblotting; Luciferases; Paclitaxel; Phosphorylation; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Receptor, ErbB-2; Signal Transduction; Time Factors

2003