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epigallocatechin gallate and Amyloidosis

epigallocatechin gallate has been researched along with Amyloidosis in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's9 (69.23)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Abskharon, R; Boyer, DR; Cheng, X; DeTure, MA; Dickson, DW; Eisenberg, DS; Ge, P; Hu, CJ; Murray, KA; Pan, H; Sawaya, MR; Seidler, PM; Vinters, HV; Williams, CK1
Drews, T; Liu, T; Marcinko, TM; Vachet, RW1
Aichler, M; Böddrich, A; Feuchtinger, A; Franko, A; Fuchs, H; Garg, D; Häring, HU; Hrabě de Angelis, M; Janik, D; Neff, F; Peter, A; Rathkolb, B; Reif, B; Rodriguez Camargo, A; Rodriguez Camargo, DC; Wanker, EE1
Claus, S; Fändrich, M; Puscalau-Girtu, I; Scheller, JS1
Andre, F; aus dem Siepen, F; Buss, SJ; Giannitsis, E; Katus, HA; Kristen, AV; Seitz, S; Steen, H1
Amero, C; French-Pacheco, L; Maya-Martinez, R; Pastor, N; Pelaez-Aguilar, AE; Rivillas-Acevedo, L; Valdes-Garcia, G1
Akaji, K; Kashiwada, Y; Kawashima, H; Kobayashi, N; Kuwabara, K; Mikawa, S; Nakajima, H; Nishitsuji, K; Saito, H; Sakashita, N; Uchimura, K1
Goto, M; Hotta, M; Kobayashi, M; Meshitsuka, S; Nojima, M; Sagesaka, YM; Shingaki, S; Suzuki, K; Ukawa, Y; Wada, Y1
Andrich, K; Bergen, HR; Bieschke, J; Hegenbart, U; Kedia, N; Kimmich, C; Schönland, S; Wanker, E1
Buss, SJ; Hardt, SE; Hunstein, W; Katus, HA; Mereles, D1
Almeida, MR; Ferreira, N; Saraiva, MJ1
Ehrhart, J; Hardy, J; Hou, H; Jeanniton, D; Morgan, D; Mori, T; Rezai-Zadeh, K; Shytle, D; Sun, N; Tan, J; Town, T; Townsend, K; Zeng, J1
Hunstein, W1

Trials

2 trial(s) available for epigallocatechin gallate and Amyloidosis

ArticleYear
Extracellular remodeling in patients with wild-type amyloidosis consuming epigallocatechin-3-gallate: preliminary results of T1 mapping by cardiac magnetic resonance imaging in a small single center study.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2015, Volume: 104, Issue:8

    Topics: Administration, Oral; Aged; Amyloid; Amyloidosis; Camellia sinensis; Capsules; Cardiomyopathies; Catechin; Contrast Media; Extracellular Matrix; Fibrosis; Gadolinium DTPA; Germany; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging, Cine; Male; Myocardium; Plant Extracts; Predictive Value of Tests; Time Factors; Treatment Outcome; Ventricular Remodeling

2015
Phase 2 trial of daily, oral epigallocatechin gallate in patients with light-chain amyloidosis.
    International journal of hematology, 2017, Volume: 105, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amyloidosis; Antioxidants; Catechin; Female; Humans; Immunoglobulin Light-chain Amyloidosis; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Tea; Treatment Outcome

2017

Other Studies

11 other study(ies) available for epigallocatechin gallate and Amyloidosis

ArticleYear
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
    Nature communications, 2022, 09-16, Volume: 13, Issue:1

    Topics: Alzheimer Disease; Amyloid; Amyloidosis; Catechin; Cryoelectron Microscopy; Drug Evaluation, Preclinical; Humans; tau Proteins; Tea

2022
Epigallocatechin-3-gallate Inhibits Cu(II)-Induced β-2-Microglobulin Amyloid Formation by Binding to the Edge of Its β-Sheets.
    Biochemistry, 2020, 03-17, Volume: 59, Issue:10

    Topics: Amyloid; Amyloidogenic Proteins; Amyloidosis; beta 2-Microglobulin; Catechin; Chromatography, Gel; Copper; Humans; Mass Spectrometry; Models, Molecular; Protein Conformation, beta-Strand; Protein Multimerization

2020
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
    Scientific reports, 2018, 01-18, Volume: 8, Issue:1

    Topics: Amyloid; Amyloidosis; Animals; Biomarkers; Catechin; Humans; Islet Amyloid Polypeptide; Mice; Mice, Transgenic; Models, Molecular; Molecular Conformation; Neuroprotective Agents; Pancreas; Protein Binding

2018
Cell assay for the identification of amyloid inhibitors in systemic AA amyloidosis.
    Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2019, Volume: 26, Issue:1

    Topics: Amyloidosis; Animals; Biological Assay; Catechin; Cell Line, Tumor; Humans; Mice; Models, Biological; Protein Aggregation, Pathological; Serum Amyloid A Protein

2019
Inhibition of Light Chain 6aJL2-R24G Amyloid Fiber Formation Associated with Light Chain Amyloidosis.
    Biochemistry, 2015, Aug-18, Volume: 54, Issue:32

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amyloid; Amyloidosis; Catechin; Humans; Immunoglobulin Light Chains; In Vitro Techniques; Melatonin; Microscopy, Electron, Transmission; Models, Molecular; Molecular Sequence Data; Mutation, Missense; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Multimerization; Quercetin; Recombinant Proteins; Rifampin; Tetracycline

2015
The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity.
    Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2016, Volume: 23, Issue:1

    Topics: Amyloid; Amyloidosis; Apolipoprotein A-I; Catechin; Cell Survival; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Protein Aggregation, Pathological; Protein Structure, Secondary; Reactive Oxygen Species

2016
Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate.
    The Journal of biological chemistry, 2017, 02-10, Volume: 292, Issue:6

    Topics: Amyloid; Amyloidosis; Catechin; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin Light Chains; Kinetics; Spectrometry, Fluorescence; Thermodynamics

2017
Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2010, Volume: 99, Issue:8

    Topics: Aged; Amyloidosis; Catechin; Female; Humans; Male; Middle Aged; Plant Extracts; Tea; Treatment Outcome; Ventricular Dysfunction, Left

2010
Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation.
    FEBS letters, 2011, Aug-04, Volume: 585, Issue:15

    Topics: Amyloid; Amyloidosis; Catechin; Curcumin; Flavonoids; Phenols; Polyphenols; Prealbumin; Protein Binding; Protein Multimerization

2011
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Sep-21, Volume: 25, Issue:38

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Catechin; Cells, Cultured; Female; Flavonoids; Mice; Mice, Transgenic; Tea

2005
Epigallocathechin-3-gallate in AL amyloidosis: a new therapeutic option?
    Blood, 2007, Sep-15, Volume: 110, Issue:6

    Topics: Amyloidosis; Anticarcinogenic Agents; Catechin; Humans; Protease Inhibitors

2007