Compounds > epigallocatechin gallate
Page last updated: 2024-08-24

epigallocatechin gallate and Alloxan Diabetes

epigallocatechin gallate has been researched along with Alloxan Diabetes in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (11.11)29.6817
2010's26 (57.78)24.3611
2020's14 (31.11)2.80

Authors

AuthorsStudies
Chen, X; He, J; He, WY; Le, Y; Tang, SQ; Wang, HB; Wang, YH1
Chen, J; Jia, Q; Mehmood, S; Yang, R; Yang, X1
Jia, Q; Li, Y; Mehmood, S; Yang, R1
Huang, AC; Lin, PH; Wu, NC; Yeh, CY; Yeh, KY; Yeh, TC1
Cai, Z; Dai, C; Gui, L; Hu, X; Liu, X; Qi, M; Wang, F; Yang, H1
Adnan, M; Badraoui, R; Ben-Nasr, H; Chappard, D; El-Feki, A; Gargouri, M; Kausar, MA; Magné, C; Saeed, M; Siddiqui, AJ; Snoussi, M; Soussi, A1
Chen, L; Chen, S; Hu, Y; Li, Z; Liu, X; Qi, S; Xiong, Y; Zhou, F; Zhu, Y1
Cai, X; Dong, X; Liu, Z; Sun, M; Wang, Y; Xie, Q; Xu, Y1
Lu, Y; Ren, Z; Yang, H; Yang, Z; Zhang, R1
Abo-Salem, OM; Ali, TM; Almalki, WH; Harisa, GI; Mehanna, OM; Younos, IH1
Gu, YH; Guo, LL; Jin, HM; Tong, JD; Yang, XH; Zhang, BL; Zhang, XM1
Huang, YW; Pang, QQ; Sheng, J; Wang, XJ; Yang, XY; Yu, CJ; Zhang, XJ; Zhu, QQ1
Hou, G; Liu, H; Liu, Q; Xi, X1
Guo, L; Guo, W; Jin, H; Li, T; Liu, X; Liu, Y; Song, Y; Sun, W; Wang, F; Wu, H; Wu, J; Yang, T; Zhang, H1
Chen, TS; Huang, CY; Kuo, CH; Kuo, WW; Liou, J; Liou, SY; Padma, VV; Pan, LF; Yao, CH; Yeh, YL1
Ha, L; Li, T; Liu, L; Liu, X; Pan, C; Song, Y; Tian, J; Wang, F; Wu, H; Wu, J; Zhou, S1
Chen, ZZ; Dou, J; Lei, SQ; Leng, Y; Meng, QT; Wu, Y; Xia, ZY; Zhao, B; Zhu, J1
Flatt, PR; Gault, VA; Millar, PJB; Pathak, NM; Pathak, V1
Abukhalil, MH; El-Missiry, MA; El-Sawi, MR; Othman, AI1
Hu, Z; Jiang, B; Li, H; Xiang, C; Xiao, X; Zhang, Y; Zhou, M1
Abdallah, DM; Ahmed, LA; El-Sayeh, BM; Rasheed, NOA1
Huang, YW; Sheng, J; Sun, B; Wang, XJ; Xu, HH; Yang, XY; Zhu, QQ1
Ashida, AH; Nagayasu, H; Ueda-Wakagi, M; Yamashita, Y1
Chen, TS; Huang, CY; Hung, MY; Kuo, WW; Lin, CC; Lin, HH; Lin, KH; Lin, YM; Liou, SY; Padma, VV; Yao, CH1
Kawamura, R; Kobayashi, T; Matsumoto, T; Taguchi, K; Watanabe, S1
Goda, T; Mochizuki, K; Suzuki, T; Uchiyama, Y1
Feng, Z; Liu, J; Long, J; Tang, Y1
Morgado, C; Pereira-Terra, P; Raposo, D; Tavares, I1
Agarwal, M; Dash, RP; Ellendula, B; Nivsarkar, M1
Funamoto, M; Hyon, SH; Ikeda, T; Masumoto, H; Minakata, K; Sakata, R; Setozaki, S; Takaori, K; Taki, T; Yamazaki, K1
Reece, EA; Xu, C; Yang, P; Zhong, J1
Lombo, C; Morgado, C; Neves, D; Tavares, I1
Borah, JC; Deka, DC; Maibam, BC; Sheikh, Y; Talukdar, NC1
Ahmedna, M; Sampath, C; Sang, S1
Han, DW; Hwang, DY; Hyon, SH; Kim, B; Kim, JE; Lee, EJ; Lee, JH; Lee, JJ; Lim, D; Lim, YJ; Shin, DM; Shin, YC; Song, SH1
Abdallah, DM; Ahmed, LA; El-Sayeh, BM; Rasheed, NO1
Adachi, S; Hata, K; Hirose, Y; Moriwaki, H; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T; Tsurumi, H1
Baba, A; Hara, Y; Kubota, M; Moriwaki, H; Ohno, T; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T; Terakura, D; Yasuda, Y1
Baluchnejadmojarad, T; Roghani, M1
Babu, PV; Liu, D; Si, H1
Chen, HM; Chen, SA; Hung, CF; Liang, YJ; Tu, CS; Yao, YD1
Janle, EM; Portocarrero, C; Zhou, Q; Zhu, Y1
Kim, SP; Song, DK; Yun, SY1
Ji, G; Li, T; Liu, J; Zhang, X1
Goda, T; Mochizuki, K; Sakurai, N; Shimada, M1

Other Studies

45 other study(ies) available for epigallocatechin gallate and Alloxan Diabetes

ArticleYear
Painful Diabetic Neuropathy Is Associated with Compromised Microglial IGF-1 Signaling Which Can Be Rescued by Green Tea Polyphenol EGCG in Mice.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Insulin-Like Growth Factor I; Mice; Microglia; Pain; Polyphenols; Tea; Tumor Necrosis Factor-alpha

2022
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats.
    Experimental biology and medicine (Maywood, N.J.), 2022, Volume: 247, Issue:16

    Topics: Animals; Catechin; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Hyperglycemia; Inflammasomes; Inflammation; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Tea

2022
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy.
    Experimental biology and medicine (Maywood, N.J.), 2022, Volume: 247, Issue:17

    Topics: Adenosine; AMP-Activated Protein Kinases; Animals; Autophagy; Beclin-1; Blood Glucose; Catechin; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Fibrosis; Hydroxyproline; Hypertrophy; Mammals; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microtubule-Associated Proteins; Rats; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1

2022
Protective Effects of Epigallocatechin Gallate for Male Sexual Dysfunction in Streptozotocin-Induced Diabetic Rats.
    International journal of molecular sciences, 2022, Aug-28, Volume: 23, Issue:17

    Topics: Animals; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Humans; Male; Rats; Streptozocin

2022
Epigallocatechin Gallate Protects Diabetes Mellitus Rats Complicated with Cardiomyopathy through TGF-β1/JNK Signaling Pathway.
    Current pharmaceutical design, 2022, Volume: 28, Issue:33

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Male; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley; Streptozocin; Transforming Growth Factor beta1

2022
(-)-Epigallocatechin gallate (EGCG) pharmacokinetics and molecular interactions towards amelioration of hyperglycemia, hyperlipidemia associated hepatorenal oxidative injury in alloxan induced diabetic mice.
    Chemico-biological interactions, 2022, Dec-01, Volume: 368

    Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Hyperglycemia; Hyperlipidemias; Liver; Mice; Oxidative Stress

2022
Copper-Epigallocatechin Gallate Enhances Therapeutic Effects of 3D-Printed Dermal Scaffolds in Mitigating Diabetic Wound Scarring.
    ACS applied materials & interfaces, 2023, Aug-16, Volume: 15, Issue:32

    Topics: Animals; Cicatrix; Copper; Diabetes Mellitus, Experimental; Hydrogels; Inflammation; Printing, Three-Dimensional; Rats; Vascular Endothelial Growth Factor A

2023
Preparation and characterization of epigallocatechin gallate, ascorbic acid, gelatin, chitosan nanoparticles and their beneficial effect on wound healing of diabetic mice.
    International journal of biological macromolecules, 2020, Apr-01, Volume: 148

    Topics: Animals; Ascorbic Acid; Catechin; Chitosan; Collagen; Diabetes Mellitus, Experimental; Gelatin; Male; Mice; Mice, Inbred ICR; Nanoparticles; Streptozocin; Wound Healing

2020
Anti‑glycolipid disorder effect of epigallocatechin‑3‑gallate on high‑fat diet and STZ‑induced T2DM in mice.
    Molecular medicine reports, 2020, Volume: 21, Issue:6

    Topics: Animals; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Endothelial Cells; Glycolipids; Hypercholesterolemia; Hyperlipidemias; Insulin Resistance; Lipids; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Sterol Regulatory Element Binding Protein 2; Streptozocin

2020
Beneficial effects of (-)-epigallocatechin-3-O-gallate on diabetic peripheral neuropathy in the rat model.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:8

    Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Peripheral Nervous System Diseases; Rats

2020
EGCG Attenuates Renal Damage via Reversing Klotho Hypermethylation in Diabetic db/db Mice and HK-2 Cells.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Catechin; Cell Line; Cell Survival; Cytokines; Diabetes Mellitus, Experimental; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Glucuronidase; Humans; Inflammation Mediators; Kidney; Klotho Proteins; Mice, Inbred C57BL; Oxidative Stress; Promoter Regions, Genetic; Transforming Growth Factor beta1

2020
EGCG targeting Notch to attenuate renal fibrosis
    Food & function, 2020, Nov-18, Volume: 11, Issue:11

    Topics: Animals; Antioxidants; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Injections, Intraperitoneal; Mice; Mice, Inbred ICR; Random Allocation; Renal Insufficiency, Chronic; Signal Transduction; Smad3 Protein; Streptozocin; Transforming Growth Factor beta

2020
[Effects of swimming and epigallocatechin gallate on interstitial proteins expression of myocardium from type 2 diabetic rats].
    Wei sheng yan jiu = Journal of hygiene research, 2021, Volume: 50, Issue:1

    Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Male; Myocardium; Rats; Rats, Sprague-Dawley; Swimming; Transforming Growth Factor beta1

2021
Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1.
    Free radical biology & medicine, 2017, Volume: 108

    Topics: Animals; Catechin; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Inflammation; Kelch-Like ECH-Associated Protein 1; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; RNA, Small Interfering; Signal Transduction; Up-Regulation

2017
Green tea epigallocatechin gallate enhances cardiac function restoration through survival signaling expression in diabetes mellitus rats with autologous adipose tissue-derived stem cells.
    Journal of applied physiology (Bethesda, Md. : 1985), 2017, Nov-01, Volume: 123, Issue:5

    Topics: Adipose Tissue; Administration, Oral; Animals; Apoptosis; Biomarkers; Blood Glucose; Catechin; Cell Survival; Cells, Cultured; Combined Modality Therapy; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Male; Myocytes, Cardiac; Rats, Wistar; Recovery of Function; Signal Transduction; Stem Cell Transplantation

2017
NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Animals; Apoptosis; Blotting, Western; Catechin; Diabetes Complications; Diabetes Mellitus, Experimental; Endoplasmic Reticulum Stress; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Testis

2017
(-)-Epigallocatechin-3-gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions.
    International journal of molecular medicine, 2017, Volume: 40, Issue:2

    Topics: Animals; Apoptosis; Cardiotonic Agents; Catechin; Diabetes Mellitus, Experimental; Hyperglycemia; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Sirtuin 1; Superoxide Dismutase

2017
Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice.
    Molecular and cellular endocrinology, 2018, 01-15, Volume: 460

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adiposity; Alanine Transaminase; Animals; Blood Glucose; Body Weight; Catechin; Corticosterone; Diabetes Mellitus, Experimental; Diet, High-Fat; Drug Therapy, Combination; Energy Intake; Exenatide; Glucose Tolerance Test; Glutathione Reductase; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Resistance; Interleukin-6; Mice, Obese

2018
Epigallocatechin-3-gallate protects against diabetic cardiomyopathy through modulating the cardiometabolic risk factors, oxidative stress, inflammation, cell death and fibrosis in streptozotocin-nicotinamide-induced diabetic rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 94

    Topics: Animals; Apoptosis; Biomarkers; Cardiotonic Agents; Catechin; Cytokines; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Male; Myocardium; Niacinamide; Oxidative Stress; Rats, Wistar; Risk Factors; Streptozocin

2017
Epigallocatechin‑3‑gallate protects from high glucose induced podocyte apoptosis via suppressing endoplasmic reticulum stress.
    Molecular medicine reports, 2017, Volume: 16, Issue:5

    Topics: Animals; Apoptosis; Caspase 12; Catechin; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glucose; Heat-Shock Proteins; Membrane Proteins; Mice; Podocytes; Protective Agents; WT1 Proteins

2017
Paradoxical cardiotoxicity of intraperitoneally-injected epigallocatechin gallate preparation in diabetic mice.
    Scientific reports, 2018, 05-18, Volume: 8, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Catechin; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Electrocardiography; Heart; HSP90 Heat-Shock Proteins; Injections, Intraperitoneal; Male; Mice; Myocardium; NADPH Oxidases; NF-kappa B; Oxidative Stress; Troponin I

2018
Wound healing can be improved by (-)-epigallocatechin gallate through targeting Notch in streptozotocin-induced diabetic mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:1

    Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Female; Inflammation; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; RAW 264.7 Cells; Receptors, Notch; Signal Transduction; Skin; Streptozocin; Wound Healing

2019
Green Tea Ameliorates Hyperglycemia by Promoting the Translocation of Glucose Transporter 4 in the Skeletal Muscle of Diabetic Rodents.
    International journal of molecular sciences, 2019, May-16, Volume: 20, Issue:10

    Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diet, High-Fat; Fructosamine; Glucose; Glucose Intolerance; Glucose Tolerance Test; Glucose Transporter Type 4; Glycated Hemoglobin; Hyperglycemia; Lipids; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Plant Extracts; Rats; Rats, Wistar; Rodentia; Streptozocin; Tea

2019
Oral administration of green tea Epigallocatechin-3-gallate reduces oxidative stress and enhances restoration of cardiac function in diabetic rats receiving autologous transplantation of adipose-derived stem cells.
    Archives of physiology and biochemistry, 2021, Volume: 127, Issue:1

    Topics: Adipocytes; Adipose Tissue; Administration, Oral; Animals; Blood Glucose; Cardiomyopathies; Catechin; Diabetes Mellitus, Experimental; Echocardiography; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Stem Cell Transplantation; Stem Cells; Tea; Transplantation, Autologous

2021
Epigallocatechin gallate attenuates ET-1-induced contraction in carotid artery from type 2 diabetic OLETF rat at chronic stage of disease.
    Life sciences, 2014, Nov-24, Volume: 118, Issue:2

    Topics: Acetylcholine; Animals; Carotid Arteries; Catechin; Chronic Disease; Diabetes Mellitus, Experimental; Endothelin-1; In Vitro Techniques; Male; NADPH Oxidases; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Rats, Inbred OLETF; Receptors, Endothelin; Superoxide Dismutase; Vasoconstriction; Vasodilation

2014
Dietary supplementation with a low dose of (-)-epigallocatechin-3-gallate reduces pro-inflammatory responses in peripheral leukocytes of non-obese type 2 diabetic GK rats.
    Journal of nutritional science and vitaminology, 2013, Volume: 59, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Catechin; Chemokines; Corn Oil; Cytokines; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Inflammation; Leukocytes; Male; Malondialdehyde; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Wistar

2013
(-)-Epigallocatechin-3-gallate attenuated myocardial mitochondrial dysfunction and autophagy in diabetic Goto-Kakizaki rats.
    Free radical research, 2014, Volume: 48, Issue:8

    Topics: Animals; Autophagy; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Mitochondria, Heart; Oxidative Stress; Rats; Rats, Wistar

2014
Nociceptive spinal cord neurons of laminae I-III exhibit oxidative stress damage during diabetic neuropathy which is prevented by early antioxidant treatment with epigallocatechin-gallate (EGCG).
    Brain research bulletin, 2015, Volume: 110

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Catechin; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperalgesia; Immunohistochemistry; Male; Neuralgia; Neuroprotective Agents; Nociceptors; Oxidative Stress; Proto-Oncogene Proteins c-fos; Rats, Wistar; Spinal Cord; Touch

2015
Increased intestinal P-glycoprotein expression and activity with progression of diabetes and its modulation by epigallocatechin-3-gallate: Evidence from pharmacokinetic studies.
    European journal of pharmacology, 2015, Nov-15, Volume: 767

    Topics: Animals; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Catechin; Diabetes Mellitus, Experimental; Disease Progression; Ileum; Intestinal Absorption; Male; Rats; Sodium-Potassium-Exchanging ATPase; Verapamil

2015
Green Tea Polyphenol Prevents Diabetic Rats From Acute Kidney Injury After Cardiopulmonary Bypass.
    The Annals of thoracic surgery, 2016, Volume: 101, Issue:4

    Topics: Acute Kidney Injury; Administration, Oral; Animals; Biopsy, Needle; Cardiopulmonary Bypass; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Follow-Up Studies; Immunohistochemistry; Kidney Function Tests; Male; Polyphenols; Preoperative Care; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reference Values; Risk Assessment; Tea; Treatment Outcome

2016
The green tea polyphenol EGCG alleviates maternal diabetes-induced neural tube defects by inhibiting DNA hypermethylation.
    American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:3

    Topics: Animals; Catechin; CpG Islands; Diabetes Mellitus, Experimental; Diabetes, Gestational; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA-Binding Proteins; Embryo, Mammalian; Female; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Mice, Inbred C57BL; Neural Tube Defects; PAX3 Transcription Factor; Pregnancy; Proteins; Transcription Factors

2016
Effects of prolonged ingestion of epigallocatechin gallate on diabetes type 1-induced vascular modifications in the erectile tissue of rats.
    International journal of impotence research, 2016, Volume: 28, Issue:4

    Topics: Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Male; Muscle, Smooth; Penis; Rats; Rats, Wistar; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2016
In vitro and in vivo anti-diabetic and hepatoprotective effects of edible pods of Parkia roxburghii and quantification of the active constituent by HPLC-PDA.
    Journal of ethnopharmacology, 2016, Sep-15, Volume: 191

    Topics: alpha-Amylases; alpha-Glucosidases; Animals; Biomarkers; Blood Glucose; Catechin; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Fabaceae; Fruit; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Liver; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Streptozocin; Time Factors

2016
In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Aldehyde Reductase; Animals; Biomarkers; Blood Glucose; Catechin; Catechols; Cell Line; Cell Survival; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet, High-Fat; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Alcohols; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Kidney; Kinetics; Male; Mice, Inbred C57BL; Myocardium; Phloretin; Retinal Pigment Epithelium; Time Factors

2016
Hyaluronic Acid/PLGA Core/Shell Fiber Matrices Loaded with EGCG Beneficial to Diabetic Wound Healing.
    Advanced healthcare materials, 2016, Volume: 5, Issue:23

    Topics: Animals; Catechin; Collagen; Diabetes Mellitus, Experimental; Fibroblasts; Hyaluronic Acid; Neovascularization, Physiologic; Polyglycolic Acid; Rats; Rats, Sprague-Dawley; Skin; Wound Healing

2016
Nephro-toxic effects of intraperitoneally injected EGCG in diabetic mice: involvement of oxidative stress, inflammation and apoptosis.
    Scientific reports, 2017, 01-18, Volume: 7

    Topics: Animals; Apoptosis; Biomarkers; Blood Urea Nitrogen; Body Weight; Caspase 3; Catechin; Cystatin C; Diabetes Mellitus, Experimental; Inflammation; Injections, Intraperitoneal; Kidney; Lipocalin-2; Male; Mice; Oxidative Stress

2017
(-)-Epigallocatechin gallate suppresses azoxymethane-induced colonic premalignant lesions in male C57BL/KsJ-db/db mice.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinoma; Catechin; Cholesterol; Colonic Neoplasms; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Insulin; Intestinal Mucosa; Leptin; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Receptor, IGF Type 1; Triglycerides

2008
Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:3

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Diabetes Mellitus, Experimental; Diethylnitrosamine; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Nonesterified; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Obesity; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1

2011
Chronic epigallocatechin-3-gallate ameliorates learning and memory deficits in diabetic rats via modulation of nitric oxide and oxidative stress.
    Behavioural brain research, 2011, Oct-31, Volume: 224, Issue:2

    Topics: Animals; Avoidance Learning; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Experimental; Hippocampus; Indazoles; Learning Disabilities; Male; Malondialdehyde; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitrites; Oxidative Stress; Rats; Rats, Wistar

2011
Epigallocatechin gallate reduces vascular inflammation in db/db mice possibly through an NF-κB-mediated mechanism.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:9

    Topics: Animals; Antioxidants; Aorta; Catechin; Cell Adhesion; Cell Line; Diabetes Mellitus, Experimental; Dietary Supplements; Endothelial Cells; Humans; Hyperglycemia; Inflammation; Male; Mice; Mice, Inbred Strains; Monocytes; Tea; Transcription Factor RelA

2012
Topical treatment with anti-oxidants and Au nanoparticles promote healing of diabetic wound through receptor for advance glycation end-products.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Dec-18, Volume: 47, Issue:5

    Topics: Administration, Topical; Animals; Antioxidants; Catechin; Cell Line; Diabetes Mellitus, Experimental; Fibroblasts; Glycation End Products, Advanced; Gold; Humans; Male; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thioctic Acid; Wound Healing

2012
Effect of long-term oral administration of green tea extract on weight gain and glucose tolerance in Zucker diabetic (ZDF) rats.
    Journal of herbal pharmacotherapy, 2005, Volume: 5, Issue:3

    Topics: Administration, Oral; Analysis of Variance; Animals; Body Weight; Catechin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Glucose; Glucose Intolerance; Hypoglycemic Agents; Male; Plant Extracts; Rats; Rats, Zucker; Tea

2005
Effects of (-)-epigallocatechin-3-gallate on pancreatic beta-cell damage in streptozotocin-induced diabetic rats.
    European journal of pharmacology, 2006, Jul-10, Volume: 541, Issue:1-2

    Topics: Animals; Antioxidants; Catechin; Cell Count; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose; Immunohistochemistry; Injections, Intraperitoneal; Insulin; Insulin-Secreting Cells; Male; Rats; Rats, Sprague-Dawley; Vitamin E; Vitamins

2006
Antidiabetic activity of lipophilic (-)-epigallocatechin-3-gallate derivative under its role of alpha-glucosidase inhibition.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2007, Volume: 61, Issue:1

    Topics: Animals; Antioxidants; Body Weight; Catechin; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Lipids; Male; Rats; Rats, Sprague-Dawley

2007
Dietary supplementation with epigallocatechin gallate elevates levels of circulating adiponectin in non-obese type-2 diabetic Goto-Kakizaki rats.
    Bioscience, biotechnology, and biochemistry, 2007, Volume: 71, Issue:8

    Topics: Adiponectin; Animals; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Lipid Metabolism; Rats; Rats, Inbred Strains; Triglycerides

2007