epidermal-growth-factor has been researched along with Keratitis* in 4 studies
4 other study(ies) available for epidermal-growth-factor and Keratitis
| Article | Year |
|---|---|
Human epidermal growth factor eyedrops for cetuximab-related filamentary keratitis.
Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Camptothecin; Cetuximab; Colorectal Neoplasms; Epidermal Growth Factor; Female; Humans; Irinotecan; Keratitis; Lung Neoplasms; Ophthalmic Solutions | 2011 |
Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation.
Mice homozygous for a disrupted transforming growth factor alpha (TGF alpha) gene are healthy and fertile, although some older mice show evidence of corneal inflammation. In contrast with TGF alpha +/- and +/+ animals, TGF alpha -/- mice have a pronounced waviness of the coat. Histological examination of the skin from TGF alpha -/- mice reveals a dramatic derangement of hair follicles. Mice with a disrupted TGF alpha gene also have curly whiskers, first evident on the day of birth. The phenotype of TGF alpha -/- mice is remarkably similar to that of the mouse mutant waved-1 (wa-1). Offspring resulting from crosses between TGF alpha -/- and wa-1 mice display the curly whisker-coat phenotype, indicating that the basis of the wa-1 phenotype is a mutation in the TGF alpha gene. These observations suggest that TGF alpha plays a pivotal role in determining skin architecture and in regulating hair development. Topics: Animals; Base Sequence; Chimera; Epidermal Growth Factor; Epithelial Cells; Eye Abnormalities; Female; Gene Deletion; Hair; Keratitis; Male; Mice; Mice, Mutant Strains; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; Oligodeoxyribonucleotides; Skin; Skin Diseases; Transforming Growth Factor alpha; Vibrissae; Wound Healing | 1993 |
Treatment of persistent epithelial defects in neurotrophic keratitis with epidermal growth factor: a preliminary open study.
We report three patients with persistent epithelial defects in the context of neurotrophic keratopathy that healed while on treatment with topically applied, mouse-derived epidermal growth factor (m-EGF). The clinical course of these patients was striking and suggests that EGF may have a potential role in the treatment of persistent epithelial defects in subjects suffering from neurotrophic keratitis. Topics: Administration, Topical; Adolescent; Adult; Cornea; Epidermal Growth Factor; Epithelium; Fluorophotometry; Humans; Keratitis; Male; Nervous System Diseases; Pilot Projects | 1992 |
The effect of dexamethasone on corneal neovascularization induced by epidermal growth factor.
Topics: Animals; Cornea; Dexamethasone; Epidermal Growth Factor; Keratitis; Male; Neovascularization, Pathologic; Peptides; Rabbits | 1981 |