eperisone has been researched along with Muscle Rigidity in 4 studies
eperisone : A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.
1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one : An aromatic ketone that is N-propylpiperidine in which a hydrogen at positon 2 of the propyl group is replaced by a p-ethylbenzoyl group.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diazepam was without effect on the extensor reflex in spinal rats." | 1.27 | Pharmacological studies of 1-(2,3-dimethyl-4-methoxyphenyl)-2-methyl-3-(1-pyrrolidinyl)-1- propanone hydrochloride (AD-2239), a centrally acting muscle relaxant. ( Furukawa, K; Hori, M; Ito, T; Kadokawa, T; Karasawa, T, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakitama, K | 1 |
| Ozawa, Y | 1 |
| Aoto, N | 1 |
| Nakamura, K | 1 |
| Ishikawa, M | 1 |
| Matsunaga, M | 1 |
| Uemura, Y | 1 |
| Yonemoto, Y | 1 |
| Kanai, K | 1 |
| Etoh, H | 1 |
| Tanaka, S | 1 |
| Atsuta, Y | 1 |
| Nishizawa, Y | 1 |
| Yamanishi, Y | 1 |
| Otsu, T | 1 |
| Kawabata, H | 1 |
| Horikomi, K | 1 |
| Tanada, H | 1 |
| Sakai, K | 1 |
| Matsubara, A | 1 |
| Mizuchi, A | 1 |
| Ito, T | 1 |
| Hori, M | 1 |
| Furukawa, K | 1 |
| Karasawa, T | 1 |
| Kadokawa, T | 1 |
4 other studies available for eperisone and Muscle Rigidity
| Article | Year |
|---|---|
Pharmacological properties of NK433, a new centrally acting muscle relaxant.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred | 1995 |
Long-lasting muscle relaxant activity of eperisone hydrochloride after percutaneous administration in rats.
Topics: Administration, Cutaneous; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dece | 1997 |
Pharmacological properties of the new centrally acting muscle relaxant (R)-(+)-3-phenyl-5-[2-(1-pyrrolidinylmethyl)butyryl]isoxazole hydrochloride.
Topics: Animals; Cats; Decerebrate State; Female; Isoxazoles; Male; Mice; Motor Activity; Muscle Relaxants, | 1997 |
Pharmacological studies of 1-(2,3-dimethyl-4-methoxyphenyl)-2-methyl-3-(1-pyrrolidinyl)-1- propanone hydrochloride (AD-2239), a centrally acting muscle relaxant.
Topics: Animals; Arousal; Baclofen; Behavior, Animal; Cats; Decerebrate State; Diazepam; Electroencephalogra | 1985 |