eperisone has been researched along with Muscle Relaxation in 5 studies
eperisone : A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.
1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one : An aromatic ketone that is N-propylpiperidine in which a hydrogen at positon 2 of the propyl group is replaced by a p-ethylbenzoyl group.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, oral eperisone has a very low bioavailability and short muscle relaxant activity, because of the profound intestinal first-pass metabolism." | 5.32 | Transdermal eperisone elicits more potent and longer-lasting muscle relaxation than oral eperisone. ( Han, OY; Jang, CG; Kim, JJ; Lee, SH; Lee, SJ; Lee, SY; Lee, WS; Lim, SC; Park, HY; Shin, YH; Yang, SI, 2004) |
| "Treatment with eperisone attenuated the contractions induced by norepinephrine and serotonin in the arteries and those by clonidine and phenylephrine in the veins." | 1.28 | Mechanisms of action of eperisone on isolated dog saphenous arteries and veins. ( Bian, K; Inoue, S; Okamura, T; Okunishi, H; Toda, N, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, SI | 1 |
| Park, HY | 1 |
| Lee, SH | 1 |
| Lee, SJ | 1 |
| Han, OY | 1 |
| Lim, SC | 1 |
| Jang, CG | 1 |
| Lee, WS | 1 |
| Shin, YH | 1 |
| Kim, JJ | 1 |
| Lee, SY | 1 |
| Matsunaga, M | 1 |
| Uemura, Y | 1 |
| Yonemoto, Y | 1 |
| Kanai, K | 1 |
| Etoh, H | 1 |
| Tanaka, S | 1 |
| Atsuta, Y | 1 |
| Nishizawa, Y | 1 |
| Yamanishi, Y | 1 |
| Otsu, T | 1 |
| Kawabata, H | 1 |
| Horikomi, K | 1 |
| Tanada, H | 1 |
| Sakai, K | 1 |
| Matsubara, A | 1 |
| Mizuchi, A | 1 |
| Inoue, S | 1 |
| Bian, K | 1 |
| Okamura, T | 1 |
| Okunishi, H | 1 |
| Toda, N | 1 |
| Iwasaki, T | 1 |
| Kurimoto, S | 1 |
5 other studies available for eperisone and Muscle Relaxation
| Article | Year |
|---|---|
Transdermal eperisone elicits more potent and longer-lasting muscle relaxation than oral eperisone.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Dose-Response Relationship, Drug; Forelimb | 2004 |
Long-lasting muscle relaxant activity of eperisone hydrochloride after percutaneous administration in rats.
Topics: Administration, Cutaneous; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dece | 1997 |
Pharmacological properties of the new centrally acting muscle relaxant (R)-(+)-3-phenyl-5-[2-(1-pyrrolidinylmethyl)butyryl]isoxazole hydrochloride.
Topics: Animals; Cats; Decerebrate State; Female; Isoxazoles; Male; Mice; Motor Activity; Muscle Relaxants, | 1997 |
Mechanisms of action of eperisone on isolated dog saphenous arteries and veins.
Topics: Animals; Arteries; Aspirin; Dogs; Drug Interactions; Electric Stimulation; Female; In Vitro Techniqu | 1989 |
[Eperisone hydrochloride in relaxation of accommodation function and improvement of eyestrain in experimental visual tasks].
Topics: Accommodation, Ocular; Adult; Asthenopia; Female; Humans; Male; Muscle Contraction; Muscle Relaxants | 1987 |