Page last updated: 2024-10-26

eperisone and Low Back Ache

eperisone has been researched along with Low Back Ache in 6 studies

eperisone : A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.
1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one : An aromatic ketone that is N-propylpiperidine in which a hydrogen at positon 2 of the propyl group is replaced by a p-ethylbenzoyl group.

Research Excerpts

ExcerptRelevanceReference
" Aceclofenac and eperisone hydrochloride are commonly prescribed drugs for acute LBP and muscle spasms."9.69Evaluation of the efficacy and safety of NVP-1203 and aceclofenac in patients with acute low back pain and muscle spasm: A randomized, double-blind, active-controlled, parallel, multicenter, phase 3 clinical trial. ( Cho, JH; Kang, CN; Kim, HJ; Kim, JH; Kim, SH; Kim, TK; Lee, JH; Lee, S; Moon, SH, 2023)
"To investigate whether respectively radial extracoporeal shock wave therapy (rESWT) or a combination of rESWT, celecoxib and eperisone (rESWT + C + E) are superior in reducing pain in patients with chronic nonspecific low back pain (cnsLBP) compared to C + E alone (a standard treatment of this condition in China)."9.41Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial. ( Feng, Z; Guo, X; Li, L; Li, Y; Peng, Z; Schmitz, C; Yan, Z; Yang, Y; Zhang, Y, 2021)
"Eperisone, an analgesic and centrally acting muscle relaxant has been in use for the treatment of low back pain (LBP)."8.93Clinical efficacy and safety of eperisone for low back pain: A systematic literature review. ( Ali Kareem, S; Bavage, S; Dhadde, SB; Durg, S, 2016)
" Aceclofenac and eperisone hydrochloride are commonly prescribed drugs for acute LBP and muscle spasms."5.69Evaluation of the efficacy and safety of NVP-1203 and aceclofenac in patients with acute low back pain and muscle spasm: A randomized, double-blind, active-controlled, parallel, multicenter, phase 3 clinical trial. ( Cho, JH; Kang, CN; Kim, HJ; Kim, JH; Kim, SH; Kim, TK; Lee, JH; Lee, S; Moon, SH, 2023)
"To investigate whether respectively radial extracoporeal shock wave therapy (rESWT) or a combination of rESWT, celecoxib and eperisone (rESWT + C + E) are superior in reducing pain in patients with chronic nonspecific low back pain (cnsLBP) compared to C + E alone (a standard treatment of this condition in China)."5.41Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial. ( Feng, Z; Guo, X; Li, L; Li, Y; Peng, Z; Schmitz, C; Yan, Z; Yang, Y; Zhang, Y, 2021)
"Eperisone hydrochloride has been recently proposed as a muscle relaxant for the treatment of muscle contracture and chronic low back pain (LBP) as it is devoid of clinically relevant sedative effects on the central nervous system (CNS)."5.13Open experience with a new myorelaxant agent for low back pain. ( Guerra, L; Sartini, S, 2008)
"Eperisone, an analgesic and centrally acting muscle relaxant has been in use for the treatment of low back pain (LBP)."4.93Clinical efficacy and safety of eperisone for low back pain: A systematic literature review. ( Ali Kareem, S; Bavage, S; Dhadde, SB; Durg, S, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Guo, X1
Li, L1
Yan, Z1
Li, Y1
Peng, Z1
Yang, Y1
Zhang, Y1
Schmitz, C1
Feng, Z1
Lee, S1
Kim, HJ1
Kim, JH1
Kim, TK1
Kang, CN1
Lee, JH1
Cho, JH1
Kim, SH1
Moon, SH1
Bavage, S1
Durg, S1
Ali Kareem, S1
Dhadde, SB1
Beltrame, A1
Grangiè, S1
Guerra, L2
Sartini, S1
Rossi, M1
Ianigro, G1
Liberatoscioli, G1
Di Castelnuovo, A1
Grimani, V1
Garofano, A1
Camposarcone, N1
Nardi, LF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized, Controlled, Single Centre Trial to Assess the Efficacy and Safety of Radial Extracorporeal Shock Wave Therapy in Patients With Chronic Non-specific Low Back Pain[NCT03337607]150 participants (Anticipated)Interventional2017-11-13Recruiting
Comparative Effects of Shockwave Therapy and Maitland's Lumbar Mobilization on Pain, Disability and Range of Motion in Patients With Mechanical Low Back Pain[NCT05404997]26 participants (Anticipated)Interventional2022-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for eperisone and Low Back Ache

ArticleYear
Clinical efficacy and safety of eperisone for low back pain: A systematic literature review.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:5

    Topics: Chronic Pain; Clonidine; Humans; Low Back Pain; Pain Measurement; Propiophenones; Treatment Outcome

2016

Trials

4 trials available for eperisone and Low Back Ache

ArticleYear
Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial.
    Journal of orthopaedic surgery and research, 2021, Dec-04, Volume: 16, Issue:1

    Topics: Celecoxib; Chronic Pain; Extracorporeal Shockwave Therapy; Humans; Low Back Pain; Propiophenones; Pr

2021
Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial.
    Journal of orthopaedic surgery and research, 2021, Dec-04, Volume: 16, Issue:1

    Topics: Celecoxib; Chronic Pain; Extracorporeal Shockwave Therapy; Humans; Low Back Pain; Propiophenones; Pr

2021
Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial.
    Journal of orthopaedic surgery and research, 2021, Dec-04, Volume: 16, Issue:1

    Topics: Celecoxib; Chronic Pain; Extracorporeal Shockwave Therapy; Humans; Low Back Pain; Propiophenones; Pr

2021
Efficacy and safety of treating chronic nonspecific low back pain with radial extracorporeal shock wave therapy (rESWT), rESWT combined with celecoxib and eperisone (C + E) or C + E alone: a prospective, randomized trial.
    Journal of orthopaedic surgery and research, 2021, Dec-04, Volume: 16, Issue:1

    Topics: Celecoxib; Chronic Pain; Extracorporeal Shockwave Therapy; Humans; Low Back Pain; Propiophenones; Pr

2021
Evaluation of the efficacy and safety of NVP-1203 and aceclofenac in patients with acute low back pain and muscle spasm: A randomized, double-blind, active-controlled, parallel, multicenter, phase 3 clinical trial.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:1

    Topics: Acute Pain; Double-Blind Method; Humans; Low Back Pain; Pain Measurement; Spasm; Treatment Outcome

2023
Open experience with a new myorelaxant agent for low back pain.
    Advances in therapy, 2008, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aged; Female; Humans; Low Back Pain; Male; Middle Aged; Muscle Relaxants, Central

2008
Eperisone versus tizanidine for treatment of chronic low back pain.
    Minerva medica, 2012, Volume: 103, Issue:3

    Topics: Analysis of Variance; Chronic Pain; Clonidine; Drug Therapy, Combination; Female; Humans; Italy; Low

2012

Other Studies

1 other study available for eperisone and Low Back Ache

ArticleYear
Clinical experience with eperisone in the treatment of acute low back pain.
    Minerva medica, 2008, Volume: 99, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Drug Administration Schedule; Female; Humans; Low Back Pain; Male

2008