eperisone has been researched along with Long QT Syndrome in 2 studies
eperisone : A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.
1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one : An aromatic ketone that is N-propylpiperidine in which a hydrogen at positon 2 of the propyl group is replaced by a p-ethylbenzoyl group.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 60-year-old man receiving nifedipine was admitted in a comatose condition 3 h after ingesting 5,000 mg of eperisone and 2." | 3.76 | A case of torsades de pointes induced by severe QT prolongation after an overdose of eperisone and triazolam in a patient receiving nifedipine. ( Amino, M; Inokuchi, S; Morita, S; Saito, T; Yamagiwa, T; Yamamoto, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haga, Y | 1 |
| Kamijo, Y | 1 |
| Yoshizawa, T | 1 |
| Hanazawa, T | 1 |
| Yokoyama, N | 1 |
| Kishino, T | 1 |
| Yamagiwa, T | 1 |
| Amino, M | 1 |
| Morita, S | 1 |
| Yamamoto, R | 1 |
| Saito, T | 1 |
| Inokuchi, S | 1 |
2 other studies available for eperisone and Long QT Syndrome
| Article | Year |
|---|---|
QTc prolongation and Torsade de Pointes induced by extreme eperisone overdose.
Topics: Drug Overdose; Electrocardiography; Female; Humans; Long QT Syndrome; Middle Aged; Parasympatholytic | 2020 |
A case of torsades de pointes induced by severe QT prolongation after an overdose of eperisone and triazolam in a patient receiving nifedipine.
Topics: Anti-Anxiety Agents; Calcium Channel Blockers; Coma; Drug Interactions; Drug Overdose; Electrocardio | 2010 |