Page last updated: 2024-10-26

eperisone and Drug Overdose

eperisone has been researched along with Drug Overdose in 4 studies

eperisone : A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.
1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one : An aromatic ketone that is N-propylpiperidine in which a hydrogen at positon 2 of the propyl group is replaced by a p-ethylbenzoyl group.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"A 60-year-old man receiving nifedipine was admitted in a comatose condition 3 h after ingesting 5,000 mg of eperisone and 2."3.76A case of torsades de pointes induced by severe QT prolongation after an overdose of eperisone and triazolam in a patient receiving nifedipine. ( Amino, M; Inokuchi, S; Morita, S; Saito, T; Yamagiwa, T; Yamamoto, R, 2010)
"Eperisone hydrochloride is a centrally acting muscle relaxant prescribed for muscle stiffness that acts by depressing the activities of α and γ efferent neurons in the spinal cord and supraspinal structures."1.40Serum concentration of eperisone hydrochloride correlates with QT interval. ( Amino, M; Inokuchi, S; Miura, N; Morita, S; Saito, T; Yamagiwa, T, 2014)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Haga, Y1
Kamijo, Y1
Yoshizawa, T1
Hanazawa, T1
Yokoyama, N1
Kishino, T1
Yamagiwa, T2
Morita, S2
Amino, M2
Miura, N1
Saito, T2
Inokuchi, S2
Yamamoto, R1
Tanno, K1
Narimatsu, E1
Takeyama, Y1
Asai, Y1

Other Studies

4 other studies available for eperisone and Drug Overdose

ArticleYear
QTc prolongation and Torsade de Pointes induced by extreme eperisone overdose.
    Clinical toxicology (Philadelphia, Pa.), 2020, Volume: 58, Issue:1

    Topics: Drug Overdose; Electrocardiography; Female; Humans; Long QT Syndrome; Middle Aged; Parasympatholytic

2020
Serum concentration of eperisone hydrochloride correlates with QT interval.
    The American journal of emergency medicine, 2014, Volume: 32, Issue:1

    Topics: Adolescent; Aged; Drug Overdose; Electrocardiography; Female; Heart; Humans; Male; Middle Aged; Musc

2014
A case of torsades de pointes induced by severe QT prolongation after an overdose of eperisone and triazolam in a patient receiving nifedipine.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:2

    Topics: Anti-Anxiety Agents; Calcium Channel Blockers; Coma; Drug Interactions; Drug Overdose; Electrocardio

2010
Infantile case of seizure induced by intoxication after accidental consumption of eperisone hydrochloride, an antispastic agent.
    The American journal of emergency medicine, 2007, Volume: 25, Issue:4

    Topics: Anticonvulsants; Coma; Drug Overdose; Female; Humans; Infant; Propiophenones; Seizures; Treatment Ou

2007