Page last updated: 2024-09-05

enzastaurin and Pancreatic Neoplasms

enzastaurin has been researched along with Pancreatic Neoplasms in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Asmar, L; Becerra, C; Boehm, KA; Gersh, RH; Gill, JF; Hozak, RR; Kuefler, PR; Mullaney, BP; Myrand, SP; Nicol, SJ; Obasaju, CK; Richards, DA; Wilfong, LS; Zhan, F; Zhao, L	1
Ambrosio, MR; Degli Uberti, EC; Gagliano, T; Gentilin, E; Molè, D; Pansini, G; Pasquali, C; Tagliati, F; Zatelli, MC	1
Ben-Josef, E; Davis, ME; Kim, AC; Lawrence, TS; Spalding, AC; Watson, R	1

Trials

1 trial(s) available for enzastaurin and Pancreatic Neoplasms

Article	Year
Gemcitabine plus enzastaurin or single-agent gemcitabine in locally advanced or metastatic pancreatic cancer: results of a phase II, randomized, noncomparative study. Investigational new drugs, 2011, Volume: 29, Issue:1 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Immunohistochemistry; Indoles; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms; Quality of Life; Treatment Outcome	2011

Article

Year

Gemcitabine plus enzastaurin or single-agent gemcitabine in locally advanced or metastatic pancreatic cancer: results of a phase II, randomized, noncomparative study.

Investigational new drugs, 2011, Volume: 29, Issue:1

Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Humans; Immunohistochemistry; Indoles; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms; Quality of Life; Treatment Outcome

2011

Other Studies

2 other study(ies) available for enzastaurin and Pancreatic Neoplasms

Article	Year
Targeting protein kinase C by Enzastaurin restrains proliferation and secretion in human pancreatic endocrine tumors. Endocrine-related cancer, 2011, Volume: 18, Issue:4 Topics: Apoptosis; Blotting, Western; Cell Proliferation; Chromogranin A; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Indoles; Insulin; Insulin Secretion; Neuroendocrine Tumors; Pancreatic Neoplasms; Protein Kinase C; Tumor Cells, Cultured	2011
Inhibition of protein kinase Cbeta by enzastaurin enhances radiation cytotoxicity in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Nov-15, Volume: 13, Issue:22 Pt 1 Topics: Animals; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Mice; Mice, Nude; Pancreatic Neoplasms; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Radiation Tolerance; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2007

Article

Year

Targeting protein kinase C by Enzastaurin restrains proliferation and secretion in human pancreatic endocrine tumors.

Endocrine-related cancer, 2011, Volume: 18, Issue:4

Topics: Apoptosis; Blotting, Western; Cell Proliferation; Chromogranin A; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Indoles; Insulin; Insulin Secretion; Neuroendocrine Tumors; Pancreatic Neoplasms; Protein Kinase C; Tumor Cells, Cultured

2011

Inhibition of protein kinase Cbeta by enzastaurin enhances radiation cytotoxicity in pancreatic cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Nov-15, Volume: 13, Issue:22 Pt 1

Topics: Animals; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Mice; Mice, Nude; Pancreatic Neoplasms; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Radiation Tolerance; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2007