enzastaurin has been researched along with Colorectal Neoplasms in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmed, K; Ahsan, A; Bui, FM; Hossain, MA; Ibrahim, SM; Rahman, MM; Soikot, SH; Somadder, PD; Sultana, T | 1 |
| Larsen, AK; Ouaret, D | 1 |
| Berglund, A; Byström, P; Cleverly, A; Darstein, C; Frödin, JE; Gawande, S; Glimelius, B; Jakobsen, A; Lahn, M; Liu, Y; Musib, L; Pfeiffer, P; Qvortrup, C; Spindler, KL | 1 |
| Berglund, A; Byström, P; Frödin, JE; Glimelius, B; Jakobsen, A; Pfeiffer, P; Qvortrup, C; Spindler, KL | 1 |
| Di Bartolomeo, M; Fuchs, M; Heinemann, V; Hossain, AM; Nicol, S; Stoffregen, C; Wolff, RA | 1 |
3 trial(s) available for enzastaurin and Colorectal Neoplasms
| Article | Year |
|---|---|
A window of opportunity phase II study of enzastaurin in chemonaive patients with asymptomatic metastatic colorectal cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Carcinoembryonic Antigen; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Indoles; L-Lactate Dehydrogenase; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Protein Kinase C; Protein Kinase C beta; Tissue Distribution | 2010 |
Long-term follow-up of chemonaive patients with asymptomatic metastatic colorectal cancer treated with enzastaurin in a window of opportunity phase II study.
Topics: Colorectal Neoplasms; Follow-Up Studies; Humans; Indoles; Survival Rate; Time Factors | 2010 |
A double-blind, randomized, placebo-controlled, phase 2 study of maintenance enzastaurin with 5-fluorouracil/leucovorin plus bevacizumab after first-line therapy for metastatic colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Disease-Free Survival; Double-Blind Method; Female; Fluorouracil; Humans; Indoles; Leucovorin; Maintenance Chemotherapy; Male; Middle Aged; Neoplasm Metastasis; Placebos; Retreatment | 2012 |
2 other study(ies) available for enzastaurin and Colorectal Neoplasms
| Article | Year |
|---|---|
Drug Repurposing and Systems Biology approaches of Enzastaurin can target potential biomarkers and critical pathways in Colorectal Cancer.
Topics: Biomarkers, Tumor; Colorectal Neoplasms; Computational Biology; Critical Pathways; Drug Repositioning; Humans; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases; Systems Biology | 2023 |
Protein kinase C β inhibition by enzastaurin leads to mitotic missegregation and preferential cytotoxicity toward colorectal cancer cells with chromosomal instability (CIN).
Topics: Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Centrosome; Chromosomal Instability; Chromosome Segregation; Colorectal Neoplasms; Humans; Indoles; Metaphase; Mitosis; Polyploidy; Protein Kinase C beta; Tumor Suppressor Protein p53 | 2014 |