Page last updated: 2024-09-05

enzastaurin and Cancer of Ovary

enzastaurin has been researched along with Cancer of Ovary in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amant, F; Bauknecht, T; Casado, A; Chekerov, R; Emerich, J; Harter, P; Mansouri, K; Myrand, SP; Nguyen, TS; Sehouli, J; Shi, P; Vergote, IB1
Vergote, I1
Amant, F; Bauknecht, T; Darstein, C; Kania, M; Michel, AL; Musib, L; Oskay-Oezcelik, G; Sehouli, J; Vergote, I1
Amant, F; Cadron, I; Drijkoningen, K; Leunen, K; Luyten, C; Mihalyi, A; Van Gorp, T; Vergote, I1
Benbrook, DM; Darcy, KM; De Geest, K; Godwin, AK; Hanjani, P; Hurteau, JA; Mannel, RS; Michelin, DP; Sill, MW; Usha, L1

Reviews

1 review(s) available for enzastaurin and Cancer of Ovary

ArticleYear
Novel therapies, including enzastaurin, in the treatment of ovarian cancer.
    Expert opinion on investigational drugs, 2014, Volume: 23, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Clinical Trials as Topic; Female; Humans; Indoles; Ovarian Neoplasms; Treatment Outcome

2014

Trials

3 trial(s) available for enzastaurin and Cancer of Ovary

ArticleYear
Randomized, phase II, placebo-controlled, double-blind study with and without enzastaurin in combination with paclitaxel and carboplatin as first-line treatment followed by maintenance treatment in advanced ovarian cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Sep-01, Volume: 31, Issue:25

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Double-Blind Method; Female; Humans; Indoles; Middle Aged; Ovarian Neoplasms; Paclitaxel; Protein Kinase C; Protein Kinase C beta

2013
Carboplatin and paclitaxel in combination with oral enzastaurin in advanced ovarian or primary peritoneal cancer: results from a safety lead-in study.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2009, Volume: 19, Issue:9

    Topics: Administration, Oral; Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Disease Progression; Drug Interactions; Female; Humans; Indoles; Middle Aged; Neoadjuvant Therapy; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms

2009
A Gynecologic Oncology Group phase II trial of the protein kinase C-beta inhibitor, enzastaurin and evaluation of markers with potential predictive and prognostic value in persistent or recurrent epithelial ovarian and primary peritoneal malignancies.
    Gynecologic oncology, 2011, Jun-01, Volume: 121, Issue:3

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Class I Phosphatidylinositol 3-Kinases; Female; Genes, p53; Humans; Indoles; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Peritoneal Neoplasms; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Vascular Endothelial Growth Factor A

2011

Other Studies

1 other study(ies) available for enzastaurin and Cancer of Ovary

ArticleYear
The impact of enzastaurin (LY317615.HCl) on CA125 biosynthesis and shedding in ovarian cancer cells.
    Gynecologic oncology, 2010, Volume: 118, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; CA-125 Antigen; Carboplatin; Cell Growth Processes; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Indoles; Ovarian Neoplasms; Paclitaxel

2010