Compounds > enzastaurin
Page last updated: 2024-09-05

enzastaurin and Cancer of Colon

enzastaurin has been researched along with Cancer of Colon in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calcagno, SR; Fields, AP; Krishna, M; Leitges, M; Murray, NR; Rak, S1
Bodo, J; Durkin, L; Hsi, ED1
Albert, S; Astorgues-Xerri, L; Benhadji, KA; Bieche, I; Emami, S; Faivre, S; Gespach, C; Hammel, P; Raymond, E; Serova, M; Theou-Anton, N; Vidaud, D; Vidaud, M1
Bailey, SN; Banks, C; Brown, TJ; Campbell, RM; Capen, A; Geeganage, S; Goode, R; Graff, JR; Hanna, KR; Huss, KL; Iversen, PW; Konicek, BW; Lewis, JE; Lynch, RL; McNulty, AM; Musib, L; Neubauer, BL; Sams, L; Thornton, D1
Fields, AP; Murray, NR1

Other Studies

5 other study(ies) available for enzastaurin and Cancer of Colon

ArticleYear
Protein kinase Cbeta is an effective target for chemoprevention of colon cancer.
    Cancer research, 2009, Feb-15, Volume: 69, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; beta Catenin; Cell Differentiation; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Indoles; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Protein Kinase C; Protein Kinase C beta

2009
Quantitative in situ detection of phosphoproteins in fixed tissues using quantum dot technology.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2009, Volume: 57, Issue:7

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Calibration; Cell Line; Colonic Neoplasms; Fixatives; fms-Like Tyrosine Kinase 3; Formaldehyde; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Leukemia, Myeloid, Acute; Mice; Mutation; Neoplasm Transplantation; Phosphoproteins; Phosphorylation; Quantum Dots; STAT5 Transcription Factor; Tissue Array Analysis; Tissue Fixation; Transplantation, Heterologous

2009
Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Dedifferentiation; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Epithelial Cells; Gene Expression Regulation, Neoplastic; Genes, ras; HCT116 Cells; HT29 Cells; Humans; Indoles; Mesenchymal Stem Cells; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Tumor Cells, Cultured

2010
The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Animals; Apoptosis; Cell Growth Processes; Colonic Neoplasms; Female; Glioblastoma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HCT116 Cells; Humans; Indoles; Male; Mice; Mice, Nude; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6; Signal Transduction; Xenograft Model Antitumor Assays

2005
Protein kinase C isozymes as therapeutic targets for treatment of human cancers.
    Advances in enzyme regulation, 2008, Volume: 48

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Humans; Indoles; Isoenzymes; K562 Cells; Lung Neoplasms; Mice; Neoplasms; Oncogenes; Protein Kinase C; Rats; Signal Transduction

2008