enzastaurin has been researched along with B-Cell Chronic Lymphocytic Leukemia in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Denk, U; Egle, A; Greil, R; Heyder, C; Hofbauer, S; Holler, C; Piñón, JD | 1 |
| Bogner, C; Decker, T; Feuerstacke, Y; Lutzny, G; Oelsner, M; Peschel, C; Ringshausen, I; Wagner, M; zum Büschenfelde, CM | 1 |
| Fournié, JJ; Laurent, G; Liffraud, C; Quillet-Mary, A; Ysebaert, L | 1 |
3 other study(ies) available for enzastaurin and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
PKCbeta is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKCbeta as a therapeutic target in chronic lymphocytic leukemia.
Topics: Aged; Aged, 80 and over; Alleles; Animals; B-Lymphocytes; CD5 Antigens; Cell Line, Tumor; Chromones; Crosses, Genetic; Female; Humans; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Mice; Mice, Knockout; Mice, Transgenic; Middle Aged; Morpholines; Neoplasm Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt | 2009 |
Recruitment of PKC-betaII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70.
Topics: Apoptosis; Humans; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Microdomains; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Kinase C beta; Proto-Oncogene Proteins c-bcl-2; Receptors, Antigen, B-Cell; Signal Transduction; ZAP-70 Protein-Tyrosine Kinase | 2010 |
Protein phosphatase-2A activation is a critical step for enzastaurin activity in chronic lymphoid leukemia cells.
Topics: Antineoplastic Agents; Cell Death; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 2; Tumor Cells, Cultured; Vidarabine | 2012 |