entinostat has been researched along with Rett Syndrome in 1 studies
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rett Syndrome is an X-linked progressive neurological disorder caused by inactivation of one allele of the MECP2 gene." | 1.37 | Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression. ( Corey, DR; Sakurai, F; Yu, D, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, D | 1 |
| Sakurai, F | 1 |
| Corey, DR | 1 |
1 other study available for entinostat and Rett Syndrome
| Article | Year |
|---|---|
Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression.
Topics: Clone Cells; Epigenesis, Genetic; Fibroblasts; Gene Expression Profiling; Humans; Methyl-CpG-Binding | 2011 |