entinostat has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 2 studies
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carraway, HE | 1 |
| Sawalha, Y | 1 |
| Gojo, I | 1 |
| Lee, MJ | 1 |
| Lee, S | 1 |
| Tomita, Y | 1 |
| Yuno, A | 1 |
| Greer, J | 1 |
| Smith, BD | 1 |
| Pratz, KW | 1 |
| Levis, MJ | 1 |
| Gore, SD | 1 |
| Ghosh, N | 1 |
| Dezern, A | 1 |
| Blackford, AL | 1 |
| Baer, MR | 1 |
| Gore, L | 1 |
| Piekarz, R | 1 |
| Trepel, JB | 1 |
| Karp, JE | 1 |
| Rivera-Del Valle, N | 1 |
| Cheng, T | 1 |
| Irwin, ME | 1 |
| Donnella, H | 1 |
| Singh, MM | 1 |
| Chandra, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Study of the Histone Deacetylase Inhibitor Entinostat (SNDX-275, NSC 706995) Plus Clofarabine for Philadelphia Chromosome-Negative, Poor Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic Leukemia in Newly Diagnosed Older Adults or in A[NCT01132573] | Phase 1 | 27 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for entinostat and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Phase 1 study of the histone deacetylase inhibitor entinostat plus clofarabine for poor-risk Philadelphia chromosome-negative (newly diagnosed older adults or adults with relapsed refractory disease) acute lymphoblastic leukemia or biphenotypic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Lineage; Clofarabine; | 2021 |
1 other study available for entinostat and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Combinatorial effects of histone deacetylase inhibitors (HDACi), vorinostat and entinostat, and adaphostin are characterized by distinct redox alterations.
Topics: Adamantane; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; DNA Fragmentation; Drug | 2018 |