Page last updated: 2024-10-31

entinostat and Inflammation

entinostat has been researched along with Inflammation in 13 studies

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Our findings indicate that single treatment with MS-275 and resveratrol can reduce stroke-mediated brain injury and inflammation observed 2 days after the pMCAO and put the rational to test repeated administration of the drugs."3.96Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia. ( Bellucci, A; Benarese, M; Mota, M; Parrella, E; Pizzi, M; Porrini, V; Rhein, S; Schwaninger, M, 2020)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's10 (76.92)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Cao, F1
Zwinderman, MRH1
van Merkerk, R1
Ettema, PE1
Quax, WJ1
Dekker, FJ1
Wu, Y1
Dou, J1
Wan, X1
Leng, Y1
Liu, X1
Chen, L2
Shen, Q1
Zhao, B1
Meng, Q1
Hou, J1
Zierfuss, B1
Weinhofer, I1
Buda, A1
Popitsch, N1
Hess, L1
Moos, V1
Hametner, S1
Kemp, S1
Köhler, W1
Forss-Petter, S1
Seiser, C1
Berger, J1
Mota, M1
Porrini, V1
Parrella, E1
Benarese, M1
Bellucci, A1
Rhein, S1
Schwaninger, M1
Pizzi, M1
Zhang, H1
Li, X1
Zhang, Q1
Yang, F3
Chu, X1
Zhang, D1
Wang, L1
Gong, Z1
Nguyen, A1
Ho, L1
Workenhe, ST1
Samson, J1
Walsh, SR1
Pol, J1
Bramson, JL1
Wan, Y1
Ryu, Y1
Kee, HJ1
Sun, S1
Seok, YM1
Choi, SY1
Kim, GR1
Kee, SJ1
Pflieger, M1
Kurz, T1
Kim, HS1
Jeong, MH1
Cantley, MD1
Fairlie, DP1
Bartold, PM1
Marino, V1
Gupta, PK1
Haynes, DR1
Yang, Y1
Wang, Y1
Li, CL1
Wang, XL1
Li, Z1
Chen, J1
Chiechio, S1
Zammataro, M1
Morales, ME1
Busceti, CL1
Drago, F1
Gereau, RW1
Copani, A1
Nicoletti, F1
Zhang, ZY3
Zhang, Z1
Schluesener, HJ3

Trials

1 trial available for entinostat and Inflammation

ArticleYear
Role of histone deacetylase expression levels and activity in the inflammatory responses of patients with chronic hepatitis B.
    Molecular medicine reports, 2017, Volume: 15, Issue:5

    Topics: Animals; Benzamides; Cytokines; Female; Gene Expression Regulation, Enzymologic; Hepatitis B, Chroni

2017

Other Studies

12 other studies available for entinostat and Inflammation

ArticleYear
Inhibitory selectivity among class I HDACs has a major impact on inflammatory gene expression in macrophages.
    European journal of medicinal chemistry, 2019, Sep-01, Volume: 177

    Topics: Anilides; Animals; Benzamides; Catalytic Domain; Gene Expression; Histone Deacetylase 1; Histone Dea

2019
Histone Deacetylase Inhibitor MS-275 Alleviates Postoperative Cognitive Dysfunction in Rats by Inhibiting Hippocampal Neuroinflammation.
    Neuroscience, 2019, 10-01, Volume: 417

    Topics: Animals; Benzamides; Cytokines; Hippocampus; Histone Deacetylase Inhibitors; Histone Deacetylases; H

2019
Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS-275.
    Annals of clinical and translational neurology, 2020, Volume: 7, Issue:11

    Topics: Acute Disease; Adrenoleukodystrophy; Adult; Autopsy; Benzamides; Foam Cells; Gene Expression Profili

2020
Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia.
    Journal of neuroinflammation, 2020, Nov-27, Volume: 17, Issue:1

    Topics: Animals; Antioxidants; Benzamides; Disease Models, Animal; Histone Deacetylase Inhibitors; Infarctio

2020
HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants.
    Cell reports, 2018, 07-17, Volume: 24, Issue:3

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Benzamides; CD8-Positive T-Lymphocytes; Cell Pol

2018
Class I histone deacetylase inhibitor MS-275 attenuates vasoconstriction and inflammation in angiotensin II-induced hypertension.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta; Benzamides; Blood Pressure; Ce

2019
Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis.
    Rheumatology (Oxford, England), 2015, Volume: 54, Issue:9

    Topics: Animals; Arthritis, Experimental; Benzamides; Bone Resorption; Cells, Cultured; Chemokines; Cytokine

2015
Selective class I histone deacetylase inhibitors suppress persistent spontaneous nociception and thermal hypersensitivity in a rat model of bee venom-induced inflammatory pain.
    Sheng li xue bao : [Acta physiologica Sinica], 2015, Oct-25, Volume: 67, Issue:5

    Topics: Animals; Bee Venoms; Benzamides; Epigenesis, Genetic; Histone Deacetylase 1; Histone Deacetylase 2;

2015
Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain.
    Molecular pharmacology, 2009, Volume: 75, Issue:5

    Topics: Amino Acids; Animals; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Enzyme Inhibitors; Epigen

2009
MS-275, an histone deacetylase inhibitor, reduces the inflammatory reaction in rat experimental autoimmune neuritis.
    Neuroscience, 2010, Aug-11, Volume: 169, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Cytokines; Demyelinating Diseases; Dru

2010
HDAC inhibitor MS-275 attenuates the inflammatory reaction in rat experimental autoimmune prostatitis.
    The Prostate, 2012, Volume: 72, Issue:1

    Topics: Animals; Autoimmune Diseases; Benzamides; Disease Models, Animal; Histone Deacetylase Inhibitors; Im

2012
Oral administration of histone deacetylase inhibitor MS-275 ameliorates neuroinflammation and cerebral amyloidosis and improves behavior in a mouse model.
    Journal of neuropathology and experimental neurology, 2013, Volume: 72, Issue:3

    Topics: Administration, Oral; Alzheimer Disease; Amyloidosis; Animals; Behavior, Animal; Benzamides; Brain;

2013