entinostat has been researched along with Infarction, Middle Cerebral Artery in 2 studies
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our findings indicate that single treatment with MS-275 and resveratrol can reduce stroke-mediated brain injury and inflammation observed 2 days after the pMCAO and put the rational to test repeated administration of the drugs." | 3.96 | Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia. ( Bellucci, A; Benarese, M; Mota, M; Parrella, E; Pizzi, M; Porrini, V; Rhein, S; Schwaninger, M, 2020) |
| "We used the mouse model of transient middle cerebral artery occlusion (MCAO) and primary cortical neurons exposed to oxygen glucose deprivation (OGD)." | 1.39 | Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window. ( Annunziato, L; Benarese, M; Branca, C; Cuomo, O; Lanzillotta, A; Pignataro, G; Pizzi, M; Sarnico, I; Spano, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mota, M | 1 |
| Porrini, V | 1 |
| Parrella, E | 1 |
| Benarese, M | 2 |
| Bellucci, A | 1 |
| Rhein, S | 1 |
| Schwaninger, M | 1 |
| Pizzi, M | 2 |
| Lanzillotta, A | 1 |
| Pignataro, G | 1 |
| Branca, C | 1 |
| Cuomo, O | 1 |
| Sarnico, I | 1 |
| Annunziato, L | 1 |
| Spano, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical, Neurophysiological and Genetical Predictors of Consciousness Recovery and Functional Outcomes After Severe Acquired Brain Injuries[NCT04495192] | 520 participants (Anticipated) | Observational [Patient Registry] | 2020-06-09 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for entinostat and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia.
Topics: Animals; Antioxidants; Benzamides; Disease Models, Animal; Histone Deacetylase Inhibitors; Infarctio | 2020 |
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window.
Topics: Acetylation; Animals; Benzamides; Brain; Brain Ischemia; Cell Hypoxia; Disease Models, Animal; Epige | 2013 |