Page last updated: 2024-10-31

entinostat and Hematologic Malignancies

entinostat has been researched along with Hematologic Malignancies in 3 studies

Research Excerpts

ExcerptRelevanceReference
"Entinostat is a well-tolerated HDACi that demonstrates promising therapeutic potential in both solid and hematologic malignancies."8.87Entinostat for treatment of solid tumors and hematologic malignancies. ( Gore, L; Knipstein, J, 2011)
"Entinostat is a well-tolerated HDACi that demonstrates promising therapeutic potential in both solid and hematologic malignancies."4.87Entinostat for treatment of solid tumors and hematologic malignancies. ( Gore, L; Knipstein, J, 2011)
"Therefore, in this review we focus upon hematologic malignancies."2.45Clinical studies of histone deacetylase inhibitors. ( Bishton, MJ; Harrison, SJ; Prince, HM, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prince, HM1
Bishton, MJ1
Harrison, SJ1
Fandy, TE1
Herman, JG1
Kerns, P1
Jiemjit, A1
Sugar, EA1
Choi, SH1
Yang, AS1
Aucott, T1
Dauses, T1
Odchimar-Reissig, R1
Licht, J1
McConnell, MJ1
Nasrallah, C1
Kim, MK1
Zhang, W1
Sun, Y1
Murgo, A1
Espinoza-Delgado, I1
Oteiza, K1
Owoeye, I1
Silverman, LR1
Gore, SD1
Carraway, HE1
Knipstein, J1
Gore, L1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Study to Compare the Efficacy of Vorinostat/Hydroxychloroquine/Maraviroc (VHM) in Controlling HIV After Treatment Interruption in Subjects Who Initiated ART During Acute HIV Infection[NCT02475915]Phase 1/Phase 215 participants (Actual)Interventional2015-01-31Completed
A Dose-Finding Trial of the Histone Deacetylase Inhibitor MS-275 (NSC 706995) in Combination With 5-Azacitidine (5AC, NSC 102816) in Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMMoL) and Acute Myeloid Leukemia (AML)[NCT00101179]Phase 163 participants (Actual)Interventional2004-11-03Completed
High Risk Myelodysplasia Treated by Azacytidine : Genetic and Epigenetic (MYRAGE)[NCT03217903]32 participants (Anticipated)Interventional2017-10-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for entinostat and Hematologic Malignancies

ArticleYear
Clinical studies of histone deacetylase inhibitors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-15, Volume: 15, Issue:12

    Topics: Antibiotics, Antineoplastic; Benzamides; Clinical Trials as Topic; Depsipeptides; Drug Therapy, Comb

2009
Entinostat for treatment of solid tumors and hematologic malignancies.
    Expert opinion on investigational drugs, 2011, Volume: 20, Issue:10

    Topics: Antineoplastic Agents; Benzamides; Hematologic Neoplasms; Histone Deacetylase Inhibitors; Humans; Mo

2011

Trials

1 trial available for entinostat and Hematologic Malignancies

ArticleYear
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.
    Blood, 2009, Sep-24, Volume: 114, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzami

2009
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.
    Blood, 2009, Sep-24, Volume: 114, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzami

2009
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.
    Blood, 2009, Sep-24, Volume: 114, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzami

2009
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.
    Blood, 2009, Sep-24, Volume: 114, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzami

2009