Page last updated: 2024-10-31

entinostat and Heart Failure

entinostat has been researched along with Heart Failure in 1 studies

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"In a rabbit model of heart failure, Entinostat diminishes heart failure related prolongation of repolarization and partially restores KCNH2 and Cav1."7.91Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure. ( Eckardt, L; Freundt, JK; Frommeyer, G; Grotthoff, JS; Hempel, G; Jacobs, AH; Lange, PS; Schäfers, M; Spieker, T; Stypmann, J; Wötzel, F, 2019)
"In a rabbit model of heart failure, Entinostat diminishes heart failure related prolongation of repolarization and partially restores KCNH2 and Cav1."3.91Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure. ( Eckardt, L; Freundt, JK; Frommeyer, G; Grotthoff, JS; Hempel, G; Jacobs, AH; Lange, PS; Schäfers, M; Spieker, T; Stypmann, J; Wötzel, F, 2019)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Freundt, JK1
Frommeyer, G1
Spieker, T1
Wötzel, F1
Grotthoff, JS1
Stypmann, J1
Hempel, G1
Schäfers, M1
Jacobs, AH1
Eckardt, L1
Lange, PS1

Other Studies

1 other study available for entinostat and Heart Failure

ArticleYear
Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure.
    BMC pharmacology & toxicology, 2019, Mar-06, Volume: 20, Issue:1

    Topics: Action Potentials; Animals; Benzamides; Calcium Channels, L-Type; ERG1 Potassium Channel; Female; Fi

2019