entinostat has been researched along with Cystic Fibrosis in 2 studies
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hutt, DM | 1 |
| Herman, D | 1 |
| Rodrigues, AP | 1 |
| Noel, S | 1 |
| Pilewski, JM | 1 |
| Matteson, J | 1 |
| Hoch, B | 1 |
| Kellner, W | 1 |
| Kelly, JW | 1 |
| Schmidt, A | 1 |
| Thomas, PJ | 1 |
| Matsumura, Y | 1 |
| Skach, WR | 1 |
| Gentzsch, M | 1 |
| Riordan, JR | 1 |
| Sorscher, EJ | 1 |
| Okiyoneda, T | 1 |
| Yates, JR | 1 |
| Lukacs, GL | 1 |
| Frizzell, RA | 1 |
| Manning, G | 1 |
| Gottesfeld, JM | 1 |
| Balch, WE | 1 |
| Barone, S | 1 |
| Cassese, E | 1 |
| Alfano, AI | 1 |
| Brindisi, M | 1 |
| Summa, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Defining Epigenetic Regulation of Immunity in Alpha-1 Anti-trypsin Deficiency[NCT02691611] | 39 participants (Actual) | Observational | 2015-12-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for entinostat and Cystic Fibrosis
| Article | Year |
|---|---|
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histone Deacetylase 6 | 2022 |
1 other study available for entinostat and Cystic Fibrosis
| Article | Year |
|---|---|
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.
Topics: Animals; Bronchi; Cell Membrane; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conducta | 2010 |