entinostat has been researched along with Alcoholism in 3 studies
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Additionally, the dose-response curve test indicated that MS-275 has a U-shape effect on ethanol self-administration with the dose of 500 µM as the most efficient dose." | 1.42 | The Class I-Specific HDAC Inhibitor MS-275 Decreases Motivation to Consume Alcohol and Relapse in Heavy Drinking Rats. ( Alaux-Cantin, S; Jeanblanc, J; Jeanblanc, V; Lemoine, S; Naassila, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bourguet, E | 1 |
| Ozdarska, K | 1 |
| Moroy, G | 1 |
| Jeanblanc, J | 2 |
| Naassila, M | 3 |
| Simon-O'Brien, E | 1 |
| Alaux-Cantin, S | 2 |
| Warnault, V | 1 |
| Buttolo, R | 1 |
| Vilpoux, C | 1 |
| Lemoine, S | 1 |
| Jeanblanc, V | 1 |
1 review available for entinostat and Alcoholism
| Article | Year |
|---|---|
Class I HDAC Inhibitors: Potential New Epigenetic Therapeutics for Alcohol Use Disorder (AUD).
Topics: Alcoholism; Animals; Epigenomics; Histone Deacetylase Inhibitors; Humans; Therapeutics | 2018 |
2 other studies available for entinostat and Alcoholism
| Article | Year |
|---|---|
The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals.
Topics: Acetylation; Alcoholism; Analysis of Variance; Animals; Benzamides; Butyric Acid; Central Nervous Sy | 2015 |
The Class I-Specific HDAC Inhibitor MS-275 Decreases Motivation to Consume Alcohol and Relapse in Heavy Drinking Rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Benzamides; Disease Models, Animal; Dose-Re | 2015 |