entinostat and Aging studies

entinostat and Aging

entinostat has been researched along with Aging in 3 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

Excerpt	Relevance	Reference
" Recent studies suggest that aging may be associated with epigenetic changes and that valproic acid (VPA), a histone deacetylase inhibitor, may reverse such changes."	3.80	HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation. ( Csernansky, JG; Dong, H; Fang, D; Gallardo, C; Gerst, N; Keegan, J; Matsumoto, M; Montalvo-Ortiz, JL; Tetsuka, K; Tucker, C, 2014)
"These results suggest that epigenetic changes at the striatal Drd2 promoter drive age-related increases in antipsychotic side effect susceptibility, and HDAC inhibitors may be an effective adjunct treatment strategy to reduce side effects in aged populations."	1.46	Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice. ( Csernansky, JG; Dong, H; Fang, D; Fisher, DW; Montalvo-Ortiz, JL; Rodríguez, G, 2017)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

3 (100.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Montalvo-Ortiz, JL	2
Fisher, DW	1
Rodríguez, G	1
Fang, D	2
Csernansky, JG	2
Dong, H	2
Keegan, J	1
Gallardo, C	1
Gerst, N	1
Tetsuka, K	1
Tucker, C	1
Matsumoto, M	1
Baltan, S	1

Studies

Montalvo-Ortiz, JL

Fisher, DW

Rodríguez, G

Fang, D

Csernansky, JG

Dong, H

Keegan, J

Gallardo, C

Gerst, N

Tetsuka, K

Tucker, C

Matsumoto, M

Baltan, S

Other Studies

3 other studies available for entinostat and Aging

Article	Year
Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice. Psychopharmacology, 2017, Volume: 234, Issue:16 Topics: Acetylation; Aging; Animals; Benzamides; Corpus Striatum; Dopamine Antagonists; Haloperidol; Histone	2017
HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:6 Topics: Acetylation; Aging; Animals; Avoidance Learning; Benzamides; Conditioning, Psychological; Dopamine A	2014
Histone deacetylase inhibitors preserve function in aging axons. Journal of neurochemistry, 2012, Volume: 123 Suppl 2 Topics: Action Potentials; Aging; Animals; Astrocytes; Axons; Benzamides; Brain; Electric Stimulation; Gene	2012

Article

Year

Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice.

Psychopharmacology, 2017, Volume: 234, Issue:16

Topics: Acetylation; Aging; Animals; Benzamides; Corpus Striatum; Dopamine Antagonists; Haloperidol; Histone

2017

HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:6

Topics: Acetylation; Aging; Animals; Avoidance Learning; Benzamides; Conditioning, Psychological; Dopamine A

2014

Histone deacetylase inhibitors preserve function in aging axons.

Journal of neurochemistry, 2012, Volume: 123 Suppl 2

Topics: Action Potentials; Aging; Animals; Astrocytes; Axons; Benzamides; Brain; Electric Stimulation; Gene

2012