Page last updated: 2024-10-31
entinostat and Aging
entinostat has been researched along with Aging in 3 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Recent studies suggest that aging may be associated with epigenetic changes and that valproic acid (VPA), a histone deacetylase inhibitor, may reverse such changes." | 3.80 | HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation. ( Csernansky, JG; Dong, H; Fang, D; Gallardo, C; Gerst, N; Keegan, J; Matsumoto, M; Montalvo-Ortiz, JL; Tetsuka, K; Tucker, C, 2014) |
| "These results suggest that epigenetic changes at the striatal Drd2 promoter drive age-related increases in antipsychotic side effect susceptibility, and HDAC inhibitors may be an effective adjunct treatment strategy to reduce side effects in aged populations." | 1.46 | Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice. ( Csernansky, JG; Dong, H; Fang, D; Fisher, DW; Montalvo-Ortiz, JL; Rodríguez, G, 2017) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Montalvo-Ortiz, JL | 2 |
| Fisher, DW | 1 |
| Rodríguez, G | 1 |
| Fang, D | 2 |
| Csernansky, JG | 2 |
| Dong, H | 2 |
| Keegan, J | 1 |
| Gallardo, C | 1 |
| Gerst, N | 1 |
| Tetsuka, K | 1 |
| Tucker, C | 1 |
| Matsumoto, M | 1 |
| Baltan, S | 1 |
Other Studies
3 other studies available for entinostat and Aging
| Article | Year |
|---|---|
Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice.
Topics: Acetylation; Aging; Animals; Benzamides; Corpus Striatum; Dopamine Antagonists; Haloperidol; Histone | 2017 |
HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation.
Topics: Acetylation; Aging; Animals; Avoidance Learning; Benzamides; Conditioning, Psychological; Dopamine A | 2014 |
Histone deacetylase inhibitors preserve function in aging axons.
Topics: Action Potentials; Aging; Animals; Astrocytes; Axons; Benzamides; Brain; Electric Stimulation; Gene | 2012 |