entecavir and Lymphoma--B-Cell--Marginal-Zone

A 65-year-old woman with a history of chronic hepatitis B was referred to our hospital for the examination of abdominal lymphadenopathy and diffuse lesions in the liver. Endoscopic ultrasound-guided fine-needle aspiration biopsy and liver biopsy were performed, and mucosa-associated lymphoid tissue (MALT) lymphoma was found in both. Based on the results of various images, a diagnosis of primary hepatic MALT lymphoma, Ann Arbor classification stage IV was reached at. Entecavir administration, H. pylori eradication therapy, and chemotherapy were performed, and remission was induced. The tumor condition remained unchanged after H. pylori eradication therapy and Entecavir administration. Subsequently, she became symptomatic, so chemotherapy was performed, leading to remission. We herein report a case of hepatic MALT lymphoma associated with chronic hepatitis B.

Topics: Aged; Anti-Bacterial Agents; Female; Guanine; Helicobacter Infections; Helicobacter pylori; Hepatitis B, Chronic; Humans; Lymphoma, B-Cell, Marginal Zone; Stomach Neoplasms

Topics: Antineoplastic Combined Chemotherapy Protocols; Guanine; Humans; Lymphoma, B-Cell, Marginal Zone; Rectal Neoplasms; Rituximab