entacapone has been researched along with Macular-Degeneration* in 1 studies
1 other study(ies) available for entacapone and Macular-Degeneration
Article | Year |
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Small-Molecule Drug Repurposing for Counteracting Phototoxic A2E Aggregation.
Despite the well-established role of oxidative stress in the pathogenesis of age-related macular degeneration (AMD), the mechanism underlying phototoxicity remains unclear. Herein, we used a drug repurposing approach to isolate an FDA-approved drug that blocks the aggregation of the photoinducible major fluorophore of lipofuscin, the bis-retinoid Topics: Drug Repositioning; Humans; Macular Degeneration; Retinal Pigment Epithelium; Retinoids | 2023 |