Page last updated: 2024-10-21

enprofylline and Pregnancy

enprofylline has been researched along with Pregnancy in 5 studies

enprofylline : Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" caused fetal apnea that was reduced from 143 +/- 45."3.68Influence of prolonged adenosine receptor blockade on fetal sleep and breathing patterns. ( Avital, A; Chernick, V; Jansen, AH; Sitar, DS, 1993)
"Enprofylline was shown to be a rather potent smooth muscle relaxant [inhibitory concentration that decreases response by 50% (IC50) = 3 X 10(-5) mol/L] and an almost equally potent cyclic adenosine monophosphate-dependent phosphodiesterase inhibitor (IC50 = 10(-4) mol/L), whereas it was a less potent cyclic guanosine monophosphate-dependent phosphodiesterase inhibitor."1.27Effects of enprofylline, a new xanthine derivate, on human pregnant myometrium. ( Andersson, RG; Berg, G; Rydén, G, 1987)
"Enprofylline was about three times more potent than theophylline."1.27Enprofylline and theophylline on small human placental arteries: studies of in vitro effects and mode of action. ( Nielsen-Kudsk, JE, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avital, A1
Jansen, AH1
Sitar, DS1
Chernick, V1
Berg, G2
Andersson, RG2
Rydén, G2
Ekelund, L1
Enhorning, G1
Nielsen-Kudsk, JE1

Other Studies

5 other studies available for enprofylline and Pregnancy

ArticleYear
Influence of prolonged adenosine receptor blockade on fetal sleep and breathing patterns.
    Respiration physiology, 1993, Volume: 91, Issue:2-3

    Topics: Animals; Apnea; Female; Fetus; Infusions, Intravenous; Phenylisopropyladenosine; Pregnancy; Purinerg

1993
Effects of enprofylline, a new xanthine derivate, on human pregnant myometrium.
    American journal of obstetrics and gynecology, 1987, Volume: 156, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Cyclic AMP; Dose-Response

1987
Effects of different phosphodiesterase-inhibiting drugs on human pregnant myometrium: an in vitro study.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 290, Issue:2

    Topics: Female; Humans; In Vitro Techniques; Muscle Relaxation; Myometrium; Papaverine; Phosphodiesterase In

1987
Pulmonary surfactant release in fetal rabbits as affected by enprofylline.
    Pediatric research, 1985, Volume: 19, Issue:10

    Topics: Animals; Bronchodilator Agents; Female; Fetus; Lung; Maternal-Fetal Exchange; Pregnancy; Pulmonary S

1985
Enprofylline and theophylline on small human placental arteries: studies of in vitro effects and mode of action.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:2

    Topics: Arteries; Bronchodilator Agents; Calcium; Dose-Response Relationship, Drug; Female; Humans; In Vitro

1985