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enprofylline and Obstructive Lung Diseases

enprofylline has been researched along with Obstructive Lung Diseases in 8 studies

enprofylline : Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

Research Excerpts

ExcerptRelevanceReference
"Long-term ambulatory Holter-monitoring was used to evaluate the arrhythmogenic effects of beta 2-agonist therapy, alone and in combination with a xanthine derivative, theophylline or enprofylline."6.66Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline. ( Conradson, TB; Eklundh, G; Olofsson, B; Pahlm, O; Persson, G, 1985)
"Theophylline was administered in identical doses, except that the final dosage increase was not made if plasma theophylline was 12 mg/ml or higher."2.67A comparison of enprofylline and theophylline in the maintenance therapy of chronic reversible obstructive airway disease. ( Abboud, RT; Boucher, S; Chapman, KR; Day, A; Hodder, RV; Hyland, RH; Kreisman, H; Peters, S; Rivington, R; York, EL, 1990)
"Long-term ambulatory Holter-monitoring was used to evaluate the arrhythmogenic effects of beta 2-agonist therapy, alone and in combination with a xanthine derivative, theophylline or enprofylline."2.66Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline. ( Conradson, TB; Eklundh, G; Olofsson, B; Pahlm, O; Persson, G, 1985)
" Neither at the low nor at the high dosage (2 +/- 4 mg/kg), giving plasma concentrations of 8."2.65Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease. ( Andersson, KE; Lunell, E; Persson, CG; Svedmyr, N, 1982)
"Enprofylline was given intravenously, 2 mg/kg, and measurements were done after ten and 30 min."1.27Cardiopulmonary effects of enprofylline. A xanthine with weak adenosine receptor antagonism in patients with severe chronic lung disease. ( Folling, M; Gulsvik, A; Vik-Mo, H, 1988)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lunell, E1
Svedmyr, N1
Andersson, KE1
Persson, CG3
Fozard, JR1
Hannon, JP1
Arnold, JD1
Courtenay-Evans, RJ1
Whitfield, R1
O'Reilly, JF1
Petrie, GR1
Higgins, AJ1
Swift, CG1
Chapman, KR1
Boucher, S1
Hyland, RH1
Day, A1
Kreisman, H1
Rivington, R1
Hodder, RV1
York, EL1
Abboud, RT1
Peters, S1
Conradson, TB1
Eklundh, G1
Olofsson, B1
Pahlm, O1
Persson, G1
Vik-Mo, H1
Gulsvik, A1
Folling, M1

Reviews

2 reviews available for enprofylline and Obstructive Lung Diseases

ArticleYear
Adenosine receptor ligands: potential as therapeutic agents in asthma and COPD.
    Pulmonary pharmacology & therapeutics, 1999, Volume: 12, Issue:2

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Humans; Ligands; Lung Diseases, Obstr

1999
Development of safer xanthine drugs for treatment of obstructive airways disease.
    The Journal of allergy and clinical immunology, 1986, Volume: 78, Issue:4 Pt 2

    Topics: Adenosine; Animals; Asthma; Brain; Cardiovascular System; Humans; Lung; Lung Diseases, Obstructive;

1986

Trials

4 trials available for enprofylline and Obstructive Lung Diseases

ArticleYear
Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:5

    Topics: Adult; Aged; Clinical Trials as Topic; Female; Forced Expiratory Volume; Hemodynamics; Humans; Lung

1982
Comparative assessment of enprofylline and theophylline for chronic obstructive airways disease in the elderly.
    Respiratory medicine, 1990, Volume: 84, Issue:3

    Topics: Aged; Bronchodilator Agents; Double-Blind Method; Female; Headache; Humans; Lung Diseases, Obstructi

1990
A comparison of enprofylline and theophylline in the maintenance therapy of chronic reversible obstructive airway disease.
    The Journal of allergy and clinical immunology, 1990, Volume: 85, Issue:2

    Topics: Adolescent; Adult; Aged; Bronchodilator Agents; Delayed-Action Preparations; Dose-Response Relations

1990
Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline.
    Chest, 1985, Volume: 88, Issue:4

    Topics: Adrenergic beta-Agonists; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind

1985

Other Studies

2 other studies available for enprofylline and Obstructive Lung Diseases

ArticleYear
Cardiopulmonary effects of enprofylline. A xanthine with weak adenosine receptor antagonism in patients with severe chronic lung disease.
    Chest, 1988, Volume: 94, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiovascular

1988
[Enprofylline--a new therapeutic possibility in asthma and other obstructive lung diseases].
    Lakartidningen, 1985, Apr-17, Volume: 82, Issue:16

    Topics: Asthma; Bronchodilator Agents; Humans; Lung Diseases, Obstructive; Xanthines

1985