Page last updated: 2024-10-21

enprofylline and Muscle Relaxation

enprofylline has been researched along with Muscle Relaxation in 6 studies

enprofylline : Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" When compounds were intraduodenally administered to the guinea pig, 1-(2'-ethoxyethyl)-, 1-(3'-methoxypropyl)-, 1-(3'-butenyl)-, and 1-[(dimethylamino)-ethyl]-3-propylxanthines, 1-methyl-7-(2'-oxopropyl)-3-propylxanthine, and denbufylline (1,3-di-n-butyl-7-(2'-oxopropyl)xanthine) effectively inhibited the acetylcholine-induced bronchospasm without heart stimulation or central nervous system-stimulation at the effective dosage range."3.68Bronchodilator activity of xanthine derivatives substituted with functional groups at the 1- or 7-position. ( Hasegawa, T; Iwasaki, N; Konno, K; Kurita, M; Miyamoto, K; Ohshima, T; Sakai, R; Sanae, F; Takagi, K; Yamamoto, Y, 1993)
"Enprofylline was more potent than theophylline in relaxing the egg albumin- or SRS-A-induced tracheal muscle tone."1.27Potent bronchodilating effects of enprofylline and theophylline on contractions induced by egg albumin or by slow reacting substance (SRS). ( Andersson, RG; Hedman, SE, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyamoto, K1
Yamamoto, Y1
Kurita, M1
Sakai, R1
Konno, K1
Sanae, F1
Ohshima, T1
Takagi, K1
Hasegawa, T1
Iwasaki, N1
Hedman, SE1
Andersson, RG2
Brackett, LE1
Shamim, MT1
Daly, JW1
Finney, MJ1
Karlsson, JA1
Persson, CG1
Obianime, AW1
Dale, MM1
Berg, G1
Ryden, G1

Other Studies

6 other studies available for enprofylline and Muscle Relaxation

ArticleYear
Bronchodilator activity of xanthine derivatives substituted with functional groups at the 1- or 7-position.
    Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10

    Topics: Administration, Oral; Animals; Bronchial Spasm; Bronchodilator Agents; Guinea Pigs; Heart Rate; Male

1993
Potent bronchodilating effects of enprofylline and theophylline on contractions induced by egg albumin or by slow reacting substance (SRS).
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:2

    Topics: Adenosine Deaminase; Albumins; Animals; Bronchi; Female; Guinea Pigs; Male; Muscle Contraction; Musc

1984
Activities of caffeine, theophylline, and enprofylline analogs as tracheal relaxants.
    Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Guinea Pigs; In Vitro Techniques; Male;

1990
Effects of bronchoconstrictors and bronchodilators on a novel human small airway preparation.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Bronchi; Bronchodilator Agents; Carbachol; Histamine; Humans; In

1985
The effect of relaxants working through different transduction mechanisms on the tonic contraction produced in rat aorta by 4 beta-phorbol dibutyrate.
    British journal of pharmacology, 1989, Volume: 97, Issue:3

    Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; In Vitro Techniques; Isoproterenol; Ma

1989
Effects of different phosphodiesterase-inhibiting drugs on human pregnant myometrium: an in vitro study.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 290, Issue:2

    Topics: Female; Humans; In Vitro Techniques; Muscle Relaxation; Myometrium; Papaverine; Phosphodiesterase In

1987