Page last updated: 2024-10-21

enprofylline and Muscle Contraction

enprofylline has been researched along with Muscle Contraction in 12 studies

enprofylline : Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Enprofylline (E) is a xanthine drug that has poor ability to antagonize physiological actions of adenosine."2.66Effects of theophylline and enprofylline on diaphragmatic contractility. ( Aubier, M; Mal, H; Murciano, D; Pariente, R; Viirès, N, 1987)
"Enprofylline was more potent than theophylline in relaxing the egg albumin- or SRS-A-induced tracheal muscle tone."1.27Potent bronchodilating effects of enprofylline and theophylline on contractions induced by egg albumin or by slow reacting substance (SRS). ( Andersson, RG; Hedman, SE, 1984)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diniz, C1
Leal, S1
Gonçalves, J1
Hedman, SE1
Andersson, RG1
Persson, CG3
Erjefält, I1
Karlsson, JA2
Orón, JD1
Cortijo, J1
Perpiñá, M1
Morcillo, EJ1
Brackett, LE1
Shamim, MT1
Daly, JW1
Finney, MJ1
Napier, FE2
Temple, DM2
Obianime, AW1
Dale, MM1
Gustafsson, B1
Murciano, D1
Aubier, M1
Viirès, N1
Mal, H1
Pariente, R1
Darmani, NA1
Broadley, KJ1

Trials

1 trial available for enprofylline and Muscle Contraction

ArticleYear
Effects of theophylline and enprofylline on diaphragmatic contractility.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:1

    Topics: Adult; Bronchodilator Agents; Diaphragm; Humans; Kinetics; Male; Muscle Contraction; Muscles; Theoph

1987

Other Studies

11 other studies available for enprofylline and Muscle Contraction

ArticleYear
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
    European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohis

2003
Potent bronchodilating effects of enprofylline and theophylline on contractions induced by egg albumin or by slow reacting substance (SRS).
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:2

    Topics: Adenosine Deaminase; Albumins; Animals; Bronchi; Female; Guinea Pigs; Male; Muscle Contraction; Musc

1984
Adenosine antagonism, a less desirable characteristic of xanthine asthma drugs?
    Acta pharmacologica et toxicologica, 1981, Volume: 49, Issue:4

    Topics: Adenosine; Animals; Asthma; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Motor Activity; Mu

1981
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:12

    Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm;

1993
Activities of caffeine, theophylline, and enprofylline analogs as tracheal relaxants.
    Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Guinea Pigs; In Vitro Techniques; Male;

1990
Effects of bronchoconstrictors and bronchodilators on a novel human small airway preparation.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Bronchi; Bronchodilator Agents; Carbachol; Histamine; Humans; In

1985
The relation between effects of adenosine, theophylline and enprofylline on the contractility of sensitized guinea-pig lung strips.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:6

    Topics: Adenosine; Animals; Antigens; Bronchodilator Agents; Dipyridamole; Female; Guinea Pigs; Histamine Re

1987
The effect of relaxants working through different transduction mechanisms on the tonic contraction produced in rat aorta by 4 beta-phorbol dibutyrate.
    British journal of pharmacology, 1989, Volume: 97, Issue:3

    Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; In Vitro Techniques; Isoproterenol; Ma

1989
The influence of xanthines on the contractile responses of PGF2 alpha and PGD2 in human parenchymal strips.
    Prostaglandins, 1989, Volume: 38, Issue:2

    Topics: Bronchodilator Agents; Dinoprost; Histamine; Humans; Lung; Muscle Contraction; Muscle, Smooth; Prost

1989
Effect of three weeks' treatment with budesonide on in vitro contractile and relaxant airway effects in the rat.
    Thorax, 1989, Volume: 44, Issue:1

    Topics: Animals; Body Weight; Budesonide; Carbachol; Culture Techniques; Glucocorticoids; Male; Muscle Contr

1989
Actions and interactions of adenosine, theophylline and enprofylline on the guinea-pig spirally cut trachea.
    European journal of pharmacology, 1986, Jun-24, Volume: 125, Issue:3

    Topics: Adenosine; Animals; Bronchodilator Agents; Carbachol; Drug Interactions; Female; Guinea Pigs; Histam

1986