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enprofylline and Bronchial Spasm

enprofylline has been researched along with Bronchial Spasm in 2 studies

enprofylline : Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.

Research Excerpts

ExcerptRelevanceReference
" When compounds were intraduodenally administered to the guinea pig, 1-(2'-ethoxyethyl)-, 1-(3'-methoxypropyl)-, 1-(3'-butenyl)-, and 1-[(dimethylamino)-ethyl]-3-propylxanthines, 1-methyl-7-(2'-oxopropyl)-3-propylxanthine, and denbufylline (1,3-di-n-butyl-7-(2'-oxopropyl)xanthine) effectively inhibited the acetylcholine-induced bronchospasm without heart stimulation or central nervous system-stimulation at the effective dosage range."3.68Bronchodilator activity of xanthine derivatives substituted with functional groups at the 1- or 7-position. ( Hasegawa, T; Iwasaki, N; Konno, K; Kurita, M; Miyamoto, K; Ohshima, T; Sakai, R; Sanae, F; Takagi, K; Yamamoto, Y, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyamoto, K1
Yamamoto, Y1
Kurita, M1
Sakai, R1
Konno, K1
Sanae, F1
Ohshima, T1
Takagi, K1
Hasegawa, T1
Iwasaki, N1
Pauwels, R1
Van Renterghem, D1
Van der Straeten, M1
Johannesson, N1
Persson, CG1

Trials

1 trial available for enprofylline and Bronchial Spasm

ArticleYear
The effect of theophylline and enprofylline on allergen-induced bronchoconstriction.
    The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:4

    Topics: Adult; Allergens; Bronchial Spasm; Drug Administration Schedule; Female; Forced Expiratory Volume; H

1985

Other Studies

1 other study available for enprofylline and Bronchial Spasm

ArticleYear
Bronchodilator activity of xanthine derivatives substituted with functional groups at the 1- or 7-position.
    Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10

    Topics: Administration, Oral; Animals; Bronchial Spasm; Bronchodilator Agents; Guinea Pigs; Heart Rate; Male

1993