enoxacin has been researched along with Urinary Tract Infections in 37 studies
Enoxacin: A broad-spectrum 6-fluoronaphthyridinone antibacterial agent that is structurally related to NALIDIXIC ACID.
enoxacin : A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea.
Urinary Tract Infections: Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-six patients with complicated, recurrent urinary tract infections were entered in a study comparing the clinical and microbiological effectiveness of enoxacin with that of co-trimoxazole (trimethoprim/sulphamethoxazole)." | 9.06 | A comparison of enoxacin and co-trimoxazole in the treatment of patients with complicated urinary tract infections. ( Cox, CE, 1988) |
| "We treated 20 patients with urinary tract infections with enoxacin, a new nalidixic acid analogue, in an open uncontrolled trial." | 9.05 | Enoxacin treatment of urinary tract infections. ( Ellis-Pegler, RB; Thomas, MG, 1985) |
| "Thirty-one patients with serious or complicated urinary tract infections were treated with oral enoxacin for between four and eight days." | 7.67 | An open study of the safety and efficacy of enoxacin in complicated urinary tract infections. ( Bates, S; Foot, M; Quaghebeur, G; Roe, M; Want, S; Williams, G, 1988) |
| "Sixty-seven elderly patients (61 female, six male) with a mean age of 82 years (range 67-95) were orally treated for 4-14 days with enoxacin (200 or 400 mg bd) for urinary tract infections in a non-comparative open study." | 7.67 | Enoxacin treatment of urinary tract infections in elderly patients. ( Huttunen, M; Kunnas, K; Saloranta, P, 1988) |
| "Minimal inhibitory concentrations (MIC) of enoxacin, nalidixic acid, pipemidic acid, norfloxacin, ciprofloxacin, ofloxacin and pefloxacin against isolates from 400 urological in-patients with complicated urinary tract infections (UTI) were determined by means of an agar dilution technique (10(4) cfu, multipointer)." | 7.67 | In vitro activity, pharmacokinetics, clinical safety and therapeutic efficacy of enoxacin in the treatment of patients with complicated urinary tract infections. ( Bartosik-Wich, B; Gutzler, F; Naber, KG; Sörgel, F, 1986) |
| "Enoxacin (ENX) was used in the treatment of 16 patients with complicated urinary tract infections." | 7.67 | [Long-term treatment and clinical evaluation of enoxacin in complicated urinary tract infections]. ( Iwase, Y; Sakagami, H; Sasaki, S; Washida, H, 1987) |
| "Enoxacin is a 6-fluoronaphthyridinone antibacterial agent with good in vitro activity against Neisseria gonorrhoeae and most Gram-negative urinary tract pathogens." | 6.39 | Enoxacin: a reappraisal of its clinical efficacy in the treatment of genitourinary tract infections. ( Patel, SS; Spencer, CM, 1996) |
| "Enoxacin was highly bioavailable (mean, 86." | 5.28 | Pharmacokinetics and bioavailability of intravenous-to-oral enoxacin in elderly patients with complicated urinary tract infections. ( Dudley, MN; Marchbanks, CR; Mayer, KH; Mikolich, DJ; Zinner, SH, 1990) |
| "Enoxacin (ENX) was administered to 69 patients with complicated urinary tract infections (UTI)." | 5.06 | [Clinical experience of enoxacin complicated urinary tract infection]. ( Arakawa, M; Kakizaki, H; Kanagawa, K; Koyanagi, T; Maru, A; Minami, S; Nakanishi, S; Sakashita, S; Togashi, M; Tsubo, S, 1988) |
| "Fifty-six patients with complicated, recurrent urinary tract infections were entered in a study comparing the clinical and microbiological effectiveness of enoxacin with that of co-trimoxazole (trimethoprim/sulphamethoxazole)." | 5.06 | A comparison of enoxacin and co-trimoxazole in the treatment of patients with complicated urinary tract infections. ( Cox, CE, 1988) |
| "Enoxacin is a new fluoroquinolone compound structurally related to nalidixic acid." | 3.76 | Enoxacin: a new fluoroquinolone. ( Bailey, EM; Jaber, LA; Rybak, MJ, 1989) |
| "Enoxacin was administered orally to 49 out-patients with urinary tract infections (UTI) at the doses of 600 mg/day and clinical effects were evaluated." | 3.67 | [Clinical studies on enoxacin in urinary tract infection]. ( Akiyama, T; Iguchi, M; Kaneko, S; Kataoka, K; Kurita, T; Nagai, N, 1988) |
| "Thirty-one patients with serious or complicated urinary tract infections were treated with oral enoxacin for between four and eight days." | 3.67 | An open study of the safety and efficacy of enoxacin in complicated urinary tract infections. ( Bates, S; Foot, M; Quaghebeur, G; Roe, M; Want, S; Williams, G, 1988) |
| " Among quinolones, the most active agents are ciprofloxacin and ofloxacin (MIC modes: 4 and 2 mg/l), so these antimicrobials could be used for the treatment of urinary tract infections caused by Corynebacterium group D2." | 3.67 | [Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity]. ( Cancet, B; Clave, D; Didier, J; Henry-Ferry, S; Marty, N, 1988) |
| "Sixty-seven elderly patients (61 female, six male) with a mean age of 82 years (range 67-95) were orally treated for 4-14 days with enoxacin (200 or 400 mg bd) for urinary tract infections in a non-comparative open study." | 3.67 | Enoxacin treatment of urinary tract infections in elderly patients. ( Huttunen, M; Kunnas, K; Saloranta, P, 1988) |
| "Twenty-three patients of greater than 70 years of age, with proven urinary tract infections were treated with 200 mg of enoxacin twice daily." | 3.67 | The pharmacokinetics of enoxacin in elderly patients. ( Baker, SL; Griggs, D; Misra, M; Wise, R, 1987) |
| "Enoxacin, a new orally absorbed broad spectrum anti-microbial agent, was used to treat 25 patients with moderate or severe urinary tract infections." | 3.67 | Enoxacin for the treatment of urinary tract infection. ( Bailey, RR; Peddie, BA, 1985) |
| "Enoxacin was well tolerated in both groups of patients; the few adverse events were mostly mild." | 2.66 | Single-dose enoxacin compared with 3-day treatment for urinary tract infection. ( Backhouse, CI; Matthews, JA, 1989) |
| " Many of the fluoroquinolone agents have once-daily dosing regimens, enhancing patient adherence." | 2.41 | The expanding role of fluoroquinolones. ( Schaeffer, AJ, 2002) |
| "Enoxacin is a new addition to the class of 4-quinolone antibacterial drugs." | 2.37 | Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. ( Henwood, JM; Monk, JP, 1988) |
| "Against respiratory tract infections with K." | 1.28 | In vivo evaluation of NM441, a new thiazeto-quinoline derivative. ( Kimura, K; Kise, M; Kitano, M; Matsuda, M; Nishino, T; Otsuki, M; Ozaki, M; Segawa, J; Shibata, K; Tomii, Y, 1991) |
| "Nalidixic acid was found to be more active in acid conditions, particularly against staphylococci, Streptococcus faecalis and Ps." | 1.27 | Laboratory evaluation of enoxacin: comparison with norfloxacin and nalidixic acid. ( Cowlishaw, A; Eley, A; Greenwood, D; Slater, G; Teoh-Chan, CH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (72.97) | 18.7374 |
| 1990's | 9 (24.32) | 18.2507 |
| 2000's | 1 (2.70) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schaeffer, AJ | 1 |
| Azadian, BS | 1 |
| Talboys, CA | 1 |
| Roberts, AP | 1 |
| Cortecchia, V | 1 |
| Beghelli, R | 1 |
| Bercovich, E | 1 |
| Scarano, P | 1 |
| Tiozzi, E | 1 |
| Martelli, A | 1 |
| De Cecco, L | 1 |
| Leone, M | 1 |
| Donabedian, H | 1 |
| O'Donnell, E | 1 |
| Drill, C | 1 |
| Lipton, LM | 1 |
| Khuder, SA | 1 |
| Burnham, JC | 1 |
| Brumfitt, W | 1 |
| Hamilton-Miller, JM | 1 |
| Walker, S | 1 |
| Patel, SS | 1 |
| Spencer, CM | 1 |
| Paukkala, E | 1 |
| Kuronen, M | 1 |
| Koponen, H | 1 |
| Ozaki, M | 1 |
| Matsuda, M | 1 |
| Tomii, Y | 1 |
| Kimura, K | 1 |
| Segawa, J | 1 |
| Kitano, M | 1 |
| Kise, M | 1 |
| Shibata, K | 1 |
| Otsuki, M | 1 |
| Nishino, T | 1 |
| Zhang, YY | 1 |
| Zhun, BY | 1 |
| Jiang, SC | 1 |
| Reid, G | 1 |
| Bruce, AW | 1 |
| Cook, RL | 1 |
| Llano, M | 1 |
| Marchbanks, CR | 1 |
| Mikolich, DJ | 1 |
| Mayer, KH | 1 |
| Zinner, SH | 1 |
| Dudley, MN | 1 |
| Desai, KM | 1 |
| Abrams, PH | 1 |
| White, LO | 1 |
| Tocci, G | 1 |
| Visco, G | 1 |
| Jaber, LA | 1 |
| Bailey, EM | 1 |
| Rybak, MJ | 1 |
| Cox, CE | 2 |
| Drylie, DM | 1 |
| Klimberg, I | 1 |
| Childs, SJ | 2 |
| Wegenke, JD | 1 |
| Malek, GH | 1 |
| Harrison, LH | 1 |
| McCullough, DL | 1 |
| Finegold, SM | 1 |
| George, WL | 1 |
| Backhouse, CI | 1 |
| Matthews, JA | 1 |
| Nakamura, S | 1 |
| Minami, A | 1 |
| Nakata, K | 1 |
| Kurobe, N | 1 |
| Kouno, K | 1 |
| Sakaguchi, Y | 1 |
| Kashimoto, S | 1 |
| Yoshida, H | 1 |
| Kojima, T | 1 |
| Ohue, T | 1 |
| Neu, HC | 2 |
| Hooper, DC | 1 |
| Wolfson, JS | 1 |
| Nagai, N | 1 |
| Kaneko, S | 1 |
| Akiyama, T | 1 |
| Kurita, T | 1 |
| Iguchi, M | 1 |
| Kataoka, K | 1 |
| Henwood, JM | 1 |
| Monk, JP | 1 |
| Togashi, M | 1 |
| Arakawa, M | 1 |
| Tsubo, S | 1 |
| Sakashita, S | 1 |
| Maru, A | 1 |
| Koyanagi, T | 1 |
| Nakanishi, S | 1 |
| Kakizaki, H | 1 |
| Minami, S | 1 |
| Kanagawa, K | 1 |
| Foot, M | 1 |
| Williams, G | 1 |
| Want, S | 1 |
| Roe, M | 1 |
| Quaghebeur, G | 1 |
| Bates, S | 1 |
| Marty, N | 1 |
| Clave, D | 1 |
| Cancet, B | 1 |
| Henry-Ferry, S | 1 |
| Didier, J | 1 |
| Teoh-Chan, CH | 1 |
| Cowlishaw, A | 1 |
| Eley, A | 1 |
| Slater, G | 1 |
| Greenwood, D | 1 |
| Huttunen, M | 1 |
| Kunnas, K | 1 |
| Saloranta, P | 1 |
| Roe, CJ | 1 |
| Becker, GJ | 1 |
| Whitworth, JA | 1 |
| Kincaid-Smith, P | 1 |
| Naber, KG | 1 |
| Sörgel, F | 1 |
| Gutzler, F | 1 |
| Bartosik-Wich, B | 1 |
| Wise, R | 1 |
| Baker, SL | 1 |
| Misra, M | 1 |
| Griggs, D | 1 |
| Washida, H | 1 |
| Sakagami, H | 1 |
| Iwase, Y | 1 |
| Sasaki, S | 1 |
| Bailey, RR | 1 |
| Peddie, BA | 1 |
| Thomas, MG | 1 |
| Ellis-Pegler, RB | 1 |
7 reviews available for enoxacin and Urinary Tract Infections
| Article | Year |
|---|---|
The expanding role of fluoroquinolones.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Ga | 2002 |
The use of enoxacin in the treatment of urinary disease: a critical review of the Italian and international literature.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteria; Enoxacin; Female; Human | 1989 |
Enoxacin: a reappraisal of its clinical efficacy in the treatment of genitourinary tract infections.
Topics: Anti-Infective Agents; Bacteria; Enoxacin; Humans; Urinary Tract Infections | 1996 |
Enoxacin: a new fluoroquinolone.
Topics: Animals; Bacterial Infections; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Drug Interac | 1989 |
Tissue penetration and clinical efficacy of enoxacin in urinary tract infections.
Topics: Enoxacin; Humans; Urinary Tract Infections | 1989 |
The fluoroquinolones: pharmacology, clinical uses, and toxicities in humans.
Topics: Anti-Bacterial Agents; Bacteria; Blood Proteins; Ciprofloxacin; Enoxacin; Fluorine; Humans; Kidney; | 1985 |
Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.
Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Enoxacin; Humans; Urinary Tract Infections | 1988 |
12 trials available for enoxacin and Urinary Tract Infections
| Article | Year |
|---|---|
Prevention of subsequent urinary tract infections in women by the use of anti-adherence antimicrobial agents: a double-blind comparison of enoxacin with co-trimoxazole.
Topics: Bacterial Adhesion; Cross-Over Studies; Double-Blind Method; Enoxacin; Epithelium; Female; Gram-Nega | 1995 |
Enoxacin relieves symptoms of recurrent urinary infections more rapidly than cefuroxime axetil.
Topics: Adult; Aged; Aged, 80 and over; Cefuroxime; Enoxacin; Humans; Middle Aged; Prodrugs; Urinary Tract I | 1993 |
[Clinical evaluation of enoxacin].
Topics: Adult; Dysentery, Bacillary; Enoxacin; Female; Gram-Negative Bacterial Infections; Humans; Male; Mid | 1991 |
Effect on urogenital flora of antibiotic therapy for urinary tract infection.
Topics: Adolescent; Adult; Aged; Amoxicillin; Ampicillin; Anti-Infective Agents, Urinary; Enoxacin; Escheric | 1990 |
A double-blind comparative trial of short-term orally administered enoxacin in the prevention of urinary infection after elective transurethral prostatectomy: a clinical and pharmacokinetic study.
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Clinical Trials as Topic; Double-Blind Method; Enoxacin | 1988 |
Enoxacin: a new fluoroquinolone.
Topics: Animals; Bacterial Infections; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Drug Interac | 1989 |
A multicenter, double-blind, trimethoprim-sulfamethoxazole controlled study of enoxacin in the treatment of patients with complicated urinary tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Double-Blind Method; Drug Combinatio | 1989 |
Single-dose enoxacin compared with 3-day treatment for urinary tract infection.
Topics: Administration, Oral; Adolescent; Adult; Aged; Enoxacin; Female; Humans; Male; Middle Aged; Urinary | 1989 |
[Clinical experience of enoxacin complicated urinary tract infection].
Topics: Adult; Aged; Aged, 80 and over; Bacteria; Bacterial Infections; Chemical Phenomena; Chemistry; Drug | 1988 |
A comparison of enoxacin and co-trimoxazole in the treatment of patients with complicated urinary tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Drug Combinat | 1988 |
Enoxacin in the treatment of complicated urinary tract infections.
Topics: Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Enoxacin; Female; Humans; Middle Aged; | 1987 |
Enoxacin treatment of urinary tract infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Enoxacin; Female; Humans; Male; Middle Aged; Naphthy | 1985 |
19 other studies available for enoxacin and Urinary Tract Infections
| Article | Year |
|---|---|
In vitro activity of lomefloxacin, a new difluorinated quinolone, against urinary bacterial isolates: comparison with enoxacin and ofloxacin.
Topics: Anti-Infective Agents; Bacteria; Enoxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Of | 1989 |
Enoxacin in urinary tract infections associated with gynecological diseases.
Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Enoxacin; Female; Ge | 1989 |
[Can urinary tract infection cause a psychosis?].
Topics: Adolescent; Anti-Infective Agents; Caffeine; Enoxacin; Female; Food-Drug Interactions; Humans; Psych | 1998 |
Enoxacin--a new fluoroquinolone.
Topics: Clinical Trials as Topic; Drug Interactions; Enoxacin; Female; Gonorrhea; Humans; Male; Urinary Trac | 1992 |
In vivo evaluation of NM441, a new thiazeto-quinoline derivative.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Dioxolanes; Dogs; Drug Evaluati | 1991 |
Pharmacokinetics and bioavailability of intravenous-to-oral enoxacin in elderly patients with complicated urinary tract infections.
Topics: Administration, Oral; Aged; Aged, 80 and over; Biological Availability; Creatinine; Enoxacin; Humans | 1990 |
[Enoxacin in the treatment of bacterial infections of the urinary tract].
Topics: Adult; Aged; Bacterial Infections; Drug Evaluation; Enoxacin; Female; Humans; Male; Middle Aged; Uri | 1989 |
In vitro and in vivo antibacterial activities of AT-4140, a new broad-spectrum quinolone.
Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquino | 1989 |
Clinical use of the quinolones.
Topics: Anti-Infective Agents; Ciprofloxacin; Diarrhea; Enoxacin; Gastrointestinal Diseases; Humans; Naphthy | 1987 |
[Clinical studies on enoxacin in urinary tract infection].
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Cystitis; Drug Evalua | 1988 |
An open study of the safety and efficacy of enoxacin in complicated urinary tract infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Evaluation; Enoxacin; Enterobacteriaceae Infections; Entero | 1988 |
[Corynebacterium group D2. Clinical study, biochemical identification and antibiotic sensitivity].
Topics: Anti-Bacterial Agents; Ciprofloxacin; Corynebacterium; Corynebacterium Infections; Drug Resistance, | 1988 |
Laboratory evaluation of enoxacin: comparison with norfloxacin and nalidixic acid.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteria; Drug Evaluation; Enoxacin; Humans; | 1985 |
Enoxacin treatment of urinary tract infections in elderly patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Catheters, Indwelling; Cystitis; Drug Evaluation; En | 1988 |
In vitro activity, pharmacokinetics, clinical safety and therapeutic efficacy of enoxacin in the treatment of patients with complicated urinary tract infections.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Enoxacin | 1986 |
The pharmacokinetics of enoxacin in elderly patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Chromatography, High Pressure Liquid; Enoxa | 1987 |
[Long-term treatment and clinical evaluation of enoxacin in complicated urinary tract infections].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Bacteria; Drug | 1987 |
Enoxacin for the treatment of urinary tract infection.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Bacterial Infections; Enoxacin; Female; Hum | 1985 |
The in-vitro activity of EN 272, a quinolone-7-carboxylic acid, in comparison with other quinolones.
Topics: Anti-Bacterial Agents; Bacteria; Enoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Naph | 1985 |