Page last updated: 2024-10-26

enoxacin and Pneumonia

enoxacin has been researched along with Pneumonia in 12 studies

Enoxacin: A broad-spectrum 6-fluoronaphthyridinone antibacterial agent that is structurally related to NALIDIXIC ACID.
enoxacin : A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"The therapeutic activity of ciprofloxacin, enoxacin, and ofloxacin was evaluated in guinea pigs with acute and chronic experimental Pseudomonas aeruginosa pneumonia."7.67Comparative evaluation of ciprofloxacin, enoxacin, and ofloxacin in experimental Pseudomonas aeruginosa pneumonia. ( Kemmerich, B; Pennington, JE; Small, GJ, 1986)
"A murine model of bacteremic Haemophilus influenzae type b pneumonia was used to evaluate the therapeutic efficacies of the quinolone antimicrobial agents enoxacin and ofloxacin compared with those of ampicillin and chloramphenicol."7.67Comparative evaluation of enoxacin, ofloxacin, ampicillin, and chloramphenicol for treatment of experimental Haemophilus influenzae pneumonia. ( Borner, K; Kemmerich, B; Pennington, JE, 1987)
"Enoxacin, a new 6-fluoroquinolone known to be active in vitro against most common pulmonary pathogens, was evaluated in comparison with ceftazidime, a third generation cephalosporin proven to be effective in the treatment of gram negative pneumonias."5.07Enoxacin therapy for severe pleuro-pulmonary infections. ( Bansal, MB; Chuah, SK; Mathai, D; Thadepalli, H, 1991)
"Ofloxacin (OFLX) or Enoxacin (ENX) was intramuscularly administered at a dose of 100 mg/kg to rats (normal and pneumonia model)."3.68[The penetration of ofloxacin and enoxacin into the alveolar spaces in rats]. ( Hayashi, Y; Ito, G; Kato, M; Takeuchi, T; Tashiro, T; Yamada, Y; Yamamoto, K; Yoshitomo, K, 1990)
"The therapeutic activity of ciprofloxacin, enoxacin, and ofloxacin was evaluated in guinea pigs with acute and chronic experimental Pseudomonas aeruginosa pneumonia."3.67Comparative evaluation of ciprofloxacin, enoxacin, and ofloxacin in experimental Pseudomonas aeruginosa pneumonia. ( Kemmerich, B; Pennington, JE; Small, GJ, 1986)
"A murine model of bacteremic Haemophilus influenzae type b pneumonia was used to evaluate the therapeutic efficacies of the quinolone antimicrobial agents enoxacin and ofloxacin compared with those of ampicillin and chloramphenicol."3.67Comparative evaluation of enoxacin, ofloxacin, ampicillin, and chloramphenicol for treatment of experimental Haemophilus influenzae pneumonia. ( Borner, K; Kemmerich, B; Pennington, JE, 1987)
"Enoxacin is a potent quinolone derivative with marked activity against gram-negative bacteria and staphylococci."2.66Penetration of enoxacin into bronchial secretions. ( Fong, IW; Simbul, M; Vandenbroucke, A, 1987)
"Enoxacin is a safe and effective alternative to parenteral treatment of lower respiratory tract infections."1.27Enoxacin in the treatment of lower respiratory tract infections. ( Arnaud, A; Frances, Y; Nourrit, J; Philip-Joet, F, 1988)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's4 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miki, F1
Saito, A1
Tomizawa, M1
Nakayama, I1
Takebe, K1
Takashima, T1
Ida, S1
Konno, K1
Oizumi, K1
Sasaki, M1
Thadepalli, H1
Mathai, D1
Bansal, MB1
Chuah, SK1
Thys, JP1
Jacobs, F1
Byl, B1
Sears, MR1
van der Linden, A1
Pollock, M1
Kato, M1
Tashiro, T1
Yoshitomo, K1
Hayashi, Y1
Ito, G1
Yamamoto, K1
Yamada, Y1
Takeuchi, T1
Adam, D1
Präuer, H1
Sörgel, F1
Zürcher, J1
Klesel, N1
Limbert, M1
Seibert, G1
Winkler, I1
Schrinner, E1
Kemmerich, B2
Small, GJ1
Pennington, JE2
Philip-Joet, F1
Nourrit, J1
Frances, Y1
Arnaud, A1
Fong, IW1
Vandenbroucke, A1
Simbul, M1
Borner, K1
Scribner, RK1
Welch, DF1
Marks, MI1

Reviews

1 review available for enoxacin and Pneumonia

ArticleYear
Role of quinolones in the treatment of bronchopulmonary infections, particularly pneumococcal and community-acquired pneumonia.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1991, Volume: 10, Issue:4

    Topics: Anti-Infective Agents; Bronchitis; Ciprofloxacin; Drug Therapy, Combination; Enoxacin; Humans; Oflox

1991

Trials

4 trials available for enoxacin and Pneumonia

ArticleYear
[Comparative study of the effectiveness of enoxacin and amoxicillin in bacterial pneumonia by a double blind method].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1984, Volume: 58, Issue:10

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Clinical Trials as

1984
Enoxacin therapy for severe pleuro-pulmonary infections.
    The Journal of the Association of Physicians of India, 1991, Volume: 39, Issue:10

    Topics: Adult; Ceftazidime; Enoxacin; Female; Gram-Negative Bacterial Infections; Hospitalization; Humans; M

1991
Role of quinolones in the treatment of bronchopulmonary infections, particularly pneumococcal and community-acquired pneumonia.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1991, Volume: 10, Issue:4

    Topics: Anti-Infective Agents; Bronchitis; Ciprofloxacin; Drug Therapy, Combination; Enoxacin; Humans; Oflox

1991
Penetration of enoxacin into bronchial secretions.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Bronchitis; Chromatography, High Pressure Liquid; Enoxacin; Fema

1987

Other Studies

8 other studies available for enoxacin and Pneumonia

ArticleYear
Mycobacterium fortuitum pneumonia--treatment with enoxacin and cotrimoxazole.
    The New Zealand medical journal, 1991, Sep-25, Volume: 104, Issue:920

    Topics: Adult; Drug Therapy, Combination; Enoxacin; Humans; Male; Mycobacterium Infections, Nontuberculous;

1991
[The penetration of ofloxacin and enoxacin into the alveolar spaces in rats].
    Nihon Kyobu Shikkan Gakkai zasshi, 1990, Volume: 28, Issue:10

    Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Enoxacin; Ofloxacin; Pneumonia; Pulmo

1990
[Enoxacin concentrations in lung tissue].
    Infection, 1989, Volume: 17 Suppl 1

    Topics: Aged; Enoxacin; Humans; Lung; Male; Middle Aged; Pneumonia; Postoperative Complications

1989
Chemotherapeutic effects of ofloxacin (HOE 280) and other quinolone-carboxylic derivates in the treatment of experimental lung infections due to Klebsiella pneumoniae DT-S in mice.
    Infection, 1986, Volume: 14 Suppl 1

    Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Enoxacin; Klebsiell

1986
Comparative evaluation of ciprofloxacin, enoxacin, and ofloxacin in experimental Pseudomonas aeruginosa pneumonia.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:3

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Enoxacin; Guinea Pigs; Kinetics; Naphthyridines; Oflo

1986
Enoxacin in the treatment of lower respiratory tract infections.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21 Suppl B

    Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Bronchiectasis; Bronchitis; Chronic Disease; Drug

1988
Comparative evaluation of enoxacin, ofloxacin, ampicillin, and chloramphenicol for treatment of experimental Haemophilus influenzae pneumonia.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:3

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Chloramphenicol; Enoxacin; Female; Haemophilus Infection

1987
Low frequency of bacterial resistance to enoxacin in vitro and in experimental pneumonia.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Enoxacin; Mutation; Naphthyrid

1985