Page last updated: 2024-10-26

enoxacin and Neoplasms

enoxacin has been researched along with Neoplasms in 8 studies

Enoxacin: A broad-spectrum 6-fluoronaphthyridinone antibacterial agent that is structurally related to NALIDIXIC ACID.
enoxacin : A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant cancers make an urgent need to develop more effective anti-cancer candidates."2.61Quinolone hybrids and their anti-cancer activities: An overview. ( Gao, F; Wang, T; Xiao, J; Zhang, X, 2019)
"Fleroxacin was also active against group JK-diphtheroids and Bacillus cereus."1.27In vitro activity of fleroxacin (Ro23-6240), a new fluorinated 4-quinolone against isolates from cancer patients. ( Bodey, GP; Ho, DH; LeBlanc, B; Rolston, K, 1988)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Azéma, J1
Guidetti, B1
Dewelle, J1
Le Calve, B1
Mijatovic, T1
Korolyov, A1
Vaysse, J1
Malet-Martino, M1
Martino, R1
Kiss, R1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Gao, F1
Zhang, X1
Wang, T1
Xiao, J1
Felicetti, T1
Manfroni, G1
Melo, S1
Villanueva, A1
Moutinho, C1
Davalos, V1
Spizzo, R1
Ivan, C1
Rossi, S1
Setien, F1
Casanovas, O1
Simo-Riudalbas, L1
Carmona, J1
Carrere, J1
Vidal, A1
Aytes, A1
Puertas, S1
Ropero, S1
Kalluri, R1
Croce, CM1
Calin, GA1
Esteller, M1
Toro, EJ1
Ostrov, DA1
Wronski, TJ1
Holliday, LS1
Rolston, K1
Ho, DH2
LeBlanc, B2
Bodey, GP2
Rolston, KV1

Reviews

3 reviews available for enoxacin and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Quinolone hybrids and their anti-cancer activities: An overview.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship

2019
Rational identification of enoxacin as a novel V-ATPase-directed osteoclast inhibitor.
    Current protein & peptide science, 2012, Volume: 13, Issue:2

    Topics: Actin Cytoskeleton; Animals; Anti-Infective Agents; Antineoplastic Agents; Candida; Candidiasis; Dru

2012

Other Studies

5 other studies available for enoxacin and Neoplasms

ArticleYear
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
    Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum

2009
Targeting miRNA dysregulation with small molecules: the case of enoxacin.
    Future medicinal chemistry, 2021, Volume: 13, Issue:15

    Topics: Drug Discovery; Enoxacin; Humans; MicroRNAs; Neoplasms; RNA Interference

2021
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Mar-15, Volume: 108, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Eno

2011
In vitro activity of fleroxacin (Ro23-6240), a new fluorinated 4-quinolone against isolates from cancer patients.
    Chemotherapy, 1988, Volume: 34, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria

1988
In vitro evaluation of S-25930 and S-25932, two new quinolones, against aerobic gram-negative isolates from cancer patients.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gram-Negativ

1987