enoxacin has been researched along with Neoplasms in 8 studies
Enoxacin: A broad-spectrum 6-fluoronaphthyridinone antibacterial agent that is structurally related to NALIDIXIC ACID.
enoxacin : A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant cancers make an urgent need to develop more effective anti-cancer candidates." | 2.61 | Quinolone hybrids and their anti-cancer activities: An overview. ( Gao, F; Wang, T; Xiao, J; Zhang, X, 2019) |
| "Fleroxacin was also active against group JK-diphtheroids and Bacillus cereus." | 1.27 | In vitro activity of fleroxacin (Ro23-6240), a new fluorinated 4-quinolone against isolates from cancer patients. ( Bodey, GP; Ho, DH; LeBlanc, B; Rolston, K, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Azéma, J | 1 |
| Guidetti, B | 1 |
| Dewelle, J | 1 |
| Le Calve, B | 1 |
| Mijatovic, T | 1 |
| Korolyov, A | 1 |
| Vaysse, J | 1 |
| Malet-Martino, M | 1 |
| Martino, R | 1 |
| Kiss, R | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Gao, F | 1 |
| Zhang, X | 1 |
| Wang, T | 1 |
| Xiao, J | 1 |
| Felicetti, T | 1 |
| Manfroni, G | 1 |
| Melo, S | 1 |
| Villanueva, A | 1 |
| Moutinho, C | 1 |
| Davalos, V | 1 |
| Spizzo, R | 1 |
| Ivan, C | 1 |
| Rossi, S | 1 |
| Setien, F | 1 |
| Casanovas, O | 1 |
| Simo-Riudalbas, L | 1 |
| Carmona, J | 1 |
| Carrere, J | 1 |
| Vidal, A | 1 |
| Aytes, A | 1 |
| Puertas, S | 1 |
| Ropero, S | 1 |
| Kalluri, R | 1 |
| Croce, CM | 1 |
| Calin, GA | 1 |
| Esteller, M | 1 |
| Toro, EJ | 1 |
| Ostrov, DA | 1 |
| Wronski, TJ | 1 |
| Holliday, LS | 1 |
| Rolston, K | 1 |
| Ho, DH | 2 |
| LeBlanc, B | 2 |
| Bodey, GP | 2 |
| Rolston, KV | 1 |
3 reviews available for enoxacin and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Quinolone hybrids and their anti-cancer activities: An overview.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship | 2019 |
Rational identification of enoxacin as a novel V-ATPase-directed osteoclast inhibitor.
Topics: Actin Cytoskeleton; Animals; Anti-Infective Agents; Antineoplastic Agents; Candida; Candidiasis; Dru | 2012 |
5 other studies available for enoxacin and Neoplasms
| Article | Year |
|---|---|
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum | 2009 |
Targeting miRNA dysregulation with small molecules: the case of enoxacin.
Topics: Drug Discovery; Enoxacin; Humans; MicroRNAs; Neoplasms; RNA Interference | 2021 |
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Eno | 2011 |
In vitro activity of fleroxacin (Ro23-6240), a new fluorinated 4-quinolone against isolates from cancer patients.
Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria | 1988 |
In vitro evaluation of S-25930 and S-25932, two new quinolones, against aerobic gram-negative isolates from cancer patients.
Topics: Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gram-Negativ | 1987 |