enoxacin has been researched along with Disease Models, Animal in 8 studies
Enoxacin: A broad-spectrum 6-fluoronaphthyridinone antibacterial agent that is structurally related to NALIDIXIC ACID.
enoxacin : A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most agents for treating osteoporosis focus primarily on anti-resorption by inhibiting osteoclast activity." | 5.62 | Bisphosphonate-enoxacin inhibit osteoclast formation and function by abrogating RANKL-induced JNK signalling pathways during osteoporosis treatment. ( Dai, M; Lai, Q; Li, X; Liu, X; Liu, Y; Mo, F; Xu, H; Xu, Q; Zhan, P; Zhang, B, 2021) |
| "Postmenopausal osteoporosis is a common systemic skeletal disease that is associated with estrogen‑deficiency." | 5.48 | Bis‑enoxacin blocks alveolar bone resorption in rats with ovariectomy‑induced osteoporosis. ( Liu, X; Lu, E; Mao, C; Qin, A; Xu, X; Zhang, X, 2018) |
| "Most agents for treating osteoporosis focus primarily on anti-resorption by inhibiting osteoclast activity." | 1.62 | Bisphosphonate-enoxacin inhibit osteoclast formation and function by abrogating RANKL-induced JNK signalling pathways during osteoporosis treatment. ( Dai, M; Lai, Q; Li, X; Liu, X; Liu, Y; Mo, F; Xu, H; Xu, Q; Zhan, P; Zhang, B, 2021) |
| "Enoxacin treatment significantly up-regulated miRNAs in dnTGFβRII CD8 T cells and effectively treated autoimmune cholangitis in dnTGFβRII mice." | 1.62 | Enoxacin Up-Regulates MicroRNA Biogenesis and Down-Regulates Cytotoxic CD8 T-Cell Function in Autoimmune Cholangitis. ( Adams, D; Bednar, KJ; Flavell, RA; Gershwin, ME; Huang, W; Itoh, A; Kachapati, K; Leung, PSC; Ridgway, WM; Wu, Y; Zhang, W, 2021) |
| "Postmenopausal osteoporosis is a common systemic skeletal disease that is associated with estrogen‑deficiency." | 1.48 | Bis‑enoxacin blocks alveolar bone resorption in rats with ovariectomy‑induced osteoporosis. ( Liu, X; Lu, E; Mao, C; Qin, A; Xu, X; Zhang, X, 2018) |
| "Ofloxacin and enoxacin were administered per os and pefloxacin and ciprofloxacin were injected subcutaneously." | 1.28 | [Activity of fluoroquinolones studied on a model of suppurative meningoencephalitis caused by Pseudomonas aeruginosa in mice]. ( Mnatsakanian, VE; Padeĭskaia, EN, 1991) |
| "Oral enoxacin was significantly more effective than tobramycin or dicloxacillin in experimental Pseudomonas aeruginosa and Staphylococcus aureus infections respectively." | 1.27 | Enoxacin pharmacokinetics and efficacy in CF-1 mice. ( Chartrand, SA; Dice, J; Marks, MI; Scribner, RK, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Redondo, M | 1 |
| Zarruk, JG | 1 |
| Ceballos, P | 1 |
| Pérez, DI | 1 |
| Pérez, C | 1 |
| Perez-Castillo, A | 1 |
| Moro, MA | 1 |
| Brea, J | 1 |
| Val, C | 1 |
| Cadavid, MI | 1 |
| Loza, MI | 1 |
| Campillo, NE | 1 |
| Martínez, A | 1 |
| Gil, C | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Xu, Q | 1 |
| Zhan, P | 1 |
| Li, X | 1 |
| Mo, F | 1 |
| Xu, H | 1 |
| Liu, Y | 1 |
| Lai, Q | 1 |
| Zhang, B | 1 |
| Dai, M | 1 |
| Liu, X | 2 |
| Kim, JA | 1 |
| Crawford, KA | 1 |
| Spada, PA | 1 |
| Martin, LR | 1 |
| Zhang, J | 1 |
| Wong, R | 1 |
| Reid, JM | 1 |
| Stewart, CF | 1 |
| Frank, TM | 1 |
| Liu, Q | 1 |
| Michalek, JE | 1 |
| Keller, C | 1 |
| Itoh, A | 1 |
| Adams, D | 1 |
| Huang, W | 1 |
| Wu, Y | 1 |
| Kachapati, K | 1 |
| Bednar, KJ | 1 |
| Leung, PSC | 1 |
| Zhang, W | 1 |
| Flavell, RA | 1 |
| Gershwin, ME | 1 |
| Ridgway, WM | 1 |
| Zhang, X | 1 |
| Xu, X | 1 |
| Mao, C | 1 |
| Qin, A | 1 |
| Lu, E | 1 |
| Padeĭskaia, EN | 1 |
| Mnatsakanian, VE | 1 |
| Chartrand, SA | 1 |
| Scribner, RK | 1 |
| Marks, MI | 1 |
| Dice, J | 1 |
8 other studies available for enoxacin and Disease Models, Animal
| Article | Year |
|---|---|
Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.
Topics: Animals; Blood-Brain Barrier; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 7; Disease | 2012 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Bisphosphonate-enoxacin inhibit osteoclast formation and function by abrogating RANKL-induced JNK signalling pathways during osteoporosis treatment.
Topics: Actins; Animals; Biomarkers; Bone and Bones; Bone Resorption; Diphosphonates; Disease Models, Animal | 2021 |
Non-chemotherapy adjuvant agents in TP53 mutant Ewing sarcoma.
Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Animals; Benzamides; Disease Models, Animal; Enoxac | 2023 |
Enoxacin Up-Regulates MicroRNA Biogenesis and Down-Regulates Cytotoxic CD8 T-Cell Function in Autoimmune Cholangitis.
Topics: Animals; Autoimmune Diseases; Cells, Cultured; Disease Models, Animal; Enoxacin; Humans; Liver Cirrh | 2021 |
Bis‑enoxacin blocks alveolar bone resorption in rats with ovariectomy‑induced osteoporosis.
Topics: Alveolar Bone Loss; Animals; Body Weight; Bone and Bones; Bone Density Conservation Agents; Diphosph | 2018 |
[Activity of fluoroquinolones studied on a model of suppurative meningoencephalitis caused by Pseudomonas aeruginosa in mice].
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Microbial; E | 1991 |
Enoxacin pharmacokinetics and efficacy in CF-1 mice.
Topics: Analysis of Variance; Animals; Anti-Infective Agents; Bacterial Infections; Disease Models, Animal; | 1987 |