enoxacin has been researched along with Body Weight in 4 studies
Enoxacin: A broad-spectrum 6-fluoronaphthyridinone antibacterial agent that is structurally related to NALIDIXIC ACID.
enoxacin : A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Postmenopausal osteoporosis is a common systemic skeletal disease that is associated with estrogen‑deficiency." | 5.48 | Bis‑enoxacin blocks alveolar bone resorption in rats with ovariectomy‑induced osteoporosis. ( Liu, X; Lu, E; Mao, C; Qin, A; Xu, X; Zhang, X, 2018) |
| "Postmenopausal osteoporosis is a common systemic skeletal disease that is associated with estrogen‑deficiency." | 1.48 | Bis‑enoxacin blocks alveolar bone resorption in rats with ovariectomy‑induced osteoporosis. ( Liu, X; Lu, E; Mao, C; Qin, A; Xu, X; Zhang, X, 2018) |
| " Pharmacokinetic parameters such as oral clearance, oral volume of distribution of the central compartment, time to reach maximum plasma concentration, absorption rate constant, and half-life in humans were predicted from animals using allometric scaling." | 1.43 | Prediction of Plasma Concentration-time Profiles of Drugs in Humans from Animals Following Oral Administration: An Allometric Approach. ( Mahmood, I, 2016) |
| " From these results, it is concluded that a 2-week treatment is sufficient to detect toxic effects of ENX on reproductive organs in male rats, and that testicular toxicity induced by ENX is associated with germ cell apoptosis." | 1.31 | Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 19). Effects of two-week repeated dosing of enoxacin on the male reproductive organs. ( Furubo, S; Kawamura, Y; Kizawa, K; Sanzen, T, 2000) |
| "Concomitant use of the bronchodilator theophylline and the antibacterial agent enoxacin has been associated with significant neurologic and other adverse effects." | 1.28 | Effect of enoxacin on theophylline neurotoxicity. ( Hoffman, A; Levy, G, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Xu, X | 1 |
| Liu, X | 1 |
| Mao, C | 1 |
| Qin, A | 1 |
| Lu, E | 1 |
| Mahmood, I | 1 |
| Kizawa, K | 1 |
| Furubo, S | 1 |
| Sanzen, T | 1 |
| Kawamura, Y | 1 |
| Hoffman, A | 1 |
| Levy, G | 1 |
4 other studies available for enoxacin and Body Weight
| Article | Year |
|---|---|
Bis‑enoxacin blocks alveolar bone resorption in rats with ovariectomy‑induced osteoporosis.
Topics: Alveolar Bone Loss; Animals; Body Weight; Bone and Bones; Bone Density Conservation Agents; Diphosph | 2018 |
Prediction of Plasma Concentration-time Profiles of Drugs in Humans from Animals Following Oral Administration: An Allometric Approach.
Topics: Administration, Oral; Animals; Body Weight; Enoxacin; Fluoroquinolones; Half-Life; Humans; Linezolid | 2016 |
Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 19). Effects of two-week repeated dosing of enoxacin on the male reproductive organs.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Apoptosis; Body Weight; Enoxacin; Epididymis; | 2000 |
Effect of enoxacin on theophylline neurotoxicity.
Topics: Animals; Body Temperature; Body Weight; Chromatography, High Pressure Liquid; Drug Interactions; Eno | 1989 |