enkephalin, leucine has been researched along with Schizophrenia in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (64.29) | 18.7374 |
| 1990's | 6 (14.29) | 18.2507 |
| 2000's | 6 (14.29) | 29.6817 |
| 2010's | 3 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brennand, KJ; Funkelstein, L; Gage, FH; Hook, V; Kim, Y; Lee, KC; Toneff, T; Ziegler, M | 1 |
| Alijaniaram, M; Fan, T; Fletcher, PJ; George, SR; Hasbi, A; O'Dowd, BF; Perreault, ML; Seeman, P; Varghese, G | 1 |
| Lewis, DA; Radchenkova, PV; Sengupta, EJ; Volk, DW; Walker, EM | 1 |
| Bignotti, S; Bocchio Chiavetto, L; Bonvicini, C; Gennarelli, M; Racagni, G; Tura, GB; Ventriglia, M | 1 |
| Khaing, ZZ; Lerman, DN; Lipska, BK; Weickert, CS; Weinberger, DR | 1 |
| Feng, GY; Gu, NF; He, L; He, Y; Lu, L; Tan, Z; Wu, SN; Zhang, CS | 1 |
| Ichikawa, H; Toru, M | 1 |
| Gambert, SR; Garthwaite, TL; Tate, PW | 1 |
| Krebs, E; Poeldinger, W; Roubicek, J | 1 |
| Comaru-Schally, AM; Schally, AV | 1 |
| Bakharev, VD; Tikhomirov, SM | 1 |
| Bouras, C; Constantinidis, J; Richard, J | 1 |
| Bowers, CY; Change, JK; Heath, RG | 1 |
| Kosterlitz, HW; McKnight, AT | 1 |
| Frederickson, RC; Geary, LE | 1 |
| Bloom, FE; Koob, GF | 1 |
| Gross, G | 1 |
| Coy, DH; Kastin, AJ; Olson, GA; Olson, RD | 1 |
| Bunney, WE; Davis, GC | 1 |
| Goedert, M; Metz, H; Otten, U | 1 |
| Benkelfat, C; Breslin, N; Dauphin, MM; Hill, JL; Kelly, TM; Pierce, PF; Roy, BF; Sunderland, T; Weinberger, DR | 1 |
| Augood, SJ; Emson, PC; Faull, RL; Harrington, KA; McKenna, PJ | 1 |
| McMurray, CT; Mikesell, MJ; Sobell, JL; Sommer, SS | 1 |
| Barron, YD; McMurray, CT; Mikesell, MJ; Nimgaonkar, VL; Sobell, JL; Sommer, SS | 1 |
| Hurd, YL; Peckys, D | 1 |
| Hurd, YL | 1 |
| Akil, H; Barchas, JD; Elliott, GR; Holman, RB; Watson, SJ | 1 |
| Copolov, D; Smith, GC | 1 |
| Bouchard, JP; Bouchard, R; Dupont, A; Labrie, F; Mérand, Y; Rouleau, D; Villeneuve, A | 1 |
| Horrobin, DF | 1 |
| Fog, R; Jørgensen, A; Veilis, B | 1 |
| Lideman, RR; Vartanian, ME | 1 |
| Ban, TA | 1 |
| Clouet, D; Verebey, K; Volavka, J | 1 |
| Bläsig, J; Cording, C; Emrich, HM; Herz, A; Kölling, A; Pirée, S; von Zerssen, D | 1 |
| Krebs, E; Roubicek, J | 1 |
| Vogt, M | 1 |
| De Wied, D; Kovács, G; Ronken, E; Wiegant, VM | 1 |
| Kalivas, PW | 1 |
| Diamond, S; Freitag, F; Mosnaim, AD; Nguyen, TD; Puente, J; Wolf, ME | 1 |
| Satoh, K | 1 |
11 review(s) available for enkephalin, leucine and Schizophrenia
| Article | Year |
|---|---|
[Neurotransmitters and neuropeptides in schizophrenia].
Topics: Acetylcholine; Brain Chemistry; Endorphins; Enkephalins; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Nerve Tissue Proteins; Neurotransmitter Agents; Norepinephrine; Schizophrenia; Serotonin; Substance P; Vasoactive Intestinal Peptide | 1984 |
[Effects of cerebral, hypothalamic and hypophyseal peptides on the central nervous system].
Topics: Acupuncture Therapy; Adrenocorticotropic Hormone; Animals; Endorphins; Enkephalins; Gonadotropin-Releasing Hormone; Humans; Hypothalamic Hormones; Melanocyte-Stimulating Hormones; MSH Release-Inhibiting Hormone; Peptides; Pituitary Hormones; Rats; Schizophrenia; Somatostatin; Thyrotropin-Releasing Hormone; Vasopressins | 1981 |
[Neuropeptide role in the etiology, pathogenesis and clinical aspects of mental diseases].
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Depressive Disorder; Drug Therapy, Combination; Endorphins; Enkephalins; Humans; Mental Disorders; Naloxone; Naltrexone; Nerve Tissue Proteins; Pituitary Hormones; Psychotropic Drugs; Schizophrenia; Substance-Related Disorders; Vasopressins | 1984 |
Putative peptide neurotransmitters in human neuropathology: a review of topography and clinical implications.
Topics: Alzheimer Disease; Brain Mapping; Central Nervous System Diseases; Cholecystokinin; Enkephalins; Humans; Huntington Disease; Limbic System; Nerve Tissue Proteins; Neurotransmitter Agents; Parkinson Disease; Schizophrenia; Substance P; Substance-Related Disorders | 1983 |
Endorphins and enkephalins.
Topics: Animals; Blood Circulation; Body Temperature Regulation; Brain Chemistry; Cats; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Emotions; Endorphins; Enkephalins; Guinea Pigs; Humans; Male; Mice; Motor Activity; Pain; Pituitary Gland; Rats; Receptors, Opioid; Respiration; Schizophrenia | 1980 |
Endogenous opioid peptides: review of physiological, pharmacological and clinical aspects.
Topics: Animals; beta-Endorphin; Blood-Brain Barrier; Brain; Endorphins; Enkephalins; Humans; Nociceptors; Peptides; Rats; Schizophrenia; Stress, Physiological; Synaptic Transmission | 1982 |
Behavioural effects of opioid peptides.
Topics: Animals; Behavior; Behavior, Animal; Drug Tolerance; Endorphins; Enkephalins; Euphoria; Humans; Learning; Memory; Mood Disorders; Naloxone; Opioid-Related Disorders; Rats; Schizophrenia | 1983 |
Behavioral effects after systemic injection of opiate peptides.
Topics: Animals; Avoidance Learning; Behavior; Cats; Chickens; Depression; Dose-Response Relationship, Drug; Drinking Behavior; Endorphins; Enkephalins; Feeding Behavior; Goldfish; Humans; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Learning; Memory; Mice; Motor Activity; Rats; Reaction Time; Schizophrenia | 1980 |
Psychopathology and endorphins.
Topics: Bipolar Disorder; Catatonia; Depression; Endorphins; Enkephalins; Humans; Mental Disorders; Narcotic Antagonists; Renal Dialysis; Schizophrenia | 1980 |
Endorphins and schizophrenia.
Topics: Amino Acid Sequence; Animals; Endorphins; Enkephalins; Humans; Hypothalamus; Molecular Sequence Data; Schizophrenia | 1992 |
Interactions between neuropeptides and dopamine neurons in the ventromedial mesencephalon.
Topics: Animals; Behavior, Animal; Cats; Cholecystokinin; Dopamine; Enkephalins; Haplorhini; Humans; Limbic System; Mesencephalon; Nerve Tissue Proteins; Neurokinin A; Neurotensin; Rats; Schizophrenia; Substance P; Swine | 1985 |
4 trial(s) available for enkephalin, leucine and Schizophrenia
| Article | Year |
|---|---|
Synthetic enkephalin analogue in treatment of schizophrenia.
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Endorphins; Enkephalins; Hallucinations; Hormones; Humans; Middle Aged; Schizophrenia | 1979 |
Endorphins in psychiatry: an overview and a hypothesis.
Topics: Animals; Behavior, Animal; Bipolar Disorder; Brain; Clinical Trials as Topic; Double-Blind Method; Endorphins; Enkephalins; Humans; Mental Disorders; Narcotic Antagonists; Narcotics; Pituitary Gland; Receptors, Opioid; Schizophrenia; Substance-Related Disorders | 1978 |
Is there some indication from behavioral effects of endorphins for their involvement in psychiatric disorders?
Topics: Animals; Behavior, Animal; Catatonia; Clinical Trials as Topic; Double-Blind Method; Endorphins; Enkephalins; Humans; Male; Naloxone; Rats; Schizophrenia; Vocalization, Animal | 1978 |
EEG and clinical profile of a synthetic analogue of methionine-enkephalin - FK 33-824.
Topics: Adult; Behavior; Clinical Trials as Topic; Depression; Double-Blind Method; Electroencephalography; Endorphins; Enkephalins; Humans; Male; Middle Aged; Placebos; Schizophrenia | 1979 |
27 other study(ies) available for enkephalin, leucine and Schizophrenia
| Article | Year |
|---|---|
Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons.
Topics: Adult; Case-Control Studies; Catecholamines; Cells, Cultured; Dynorphins; Enkephalins; Exocytosis; Female; Humans; Induced Pluripotent Stem Cells; Infant, Newborn; Male; Neural Stem Cells; Neurons; Schizophrenia | 2014 |
The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia.
Topics: Amphetamine; Animals; Basal Ganglia; Behavior, Animal; Brain; Corpus Striatum; Dopamine; Dopamine Agents; Dynorphins; Enkephalins; Globus Pallidus; Humans; Immunoenzyme Techniques; Male; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia | 2010 |
Cortical opioid markers in schizophrenia and across postnatal development.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Enkephalins; Female; Haloperidol; Humans; Macaca fascicularis; Male; Middle Aged; Olanzapine; Polymerase Chain Reaction; Prefrontal Cortex; Protein Precursors; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger; Schizophrenia | 2012 |
Allelic variation in the human prodynorphin gene promoter and schizophrenia.
Topics: Alleles; Case-Control Studies; Enkephalins; Genetic Variation; Genotype; Glycine; Humans; Italy; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors; Receptors, Dopamine D2; Receptors, Dopamine D3; Risk Factors; Schizophrenia; White People | 2002 |
Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs.
Topics: Animals; Animals, Newborn; Antipsychotic Agents; Brain; Clozapine; Dopamine; Enkephalins; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Haloperidol; Ibotenic Acid; In Situ Hybridization; Isoenzymes; Male; Models, Animal; Neurotensin; Protein Precursors; Rats; Receptors, Dopamine; RNA, Messenger; Schizophrenia; Time Factors | 2003 |
Polymorphism of Prodynorphin promoter is associated with schizophrenia in Chinese population.
Topics: Adult; Asian People; Enkephalins; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein Precursors; Schizophrenia | 2004 |
Clinical implications of the endogenous opiates: II. Behavioral and psychiatric aspects.
Topics: Behavior; Endorphins; Enkephalins; Female; Humans; Male; Memory; Mood Disorders; Receptors, Opioid; Schizophrenia; Sexual Behavior | 1983 |
Classification of endorphins/enkephalins in brain physiology and pathology (based on EEG and clinical study of synthetically-modified methionine-enkephalin).
Topics: Adult; Antipsychotic Agents; Brain; Chemical Phenomena; Chemistry; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Depressive Disorder; Electroencephalography; Endorphins; Enkephalins; Female; Growth Hormone; Hormones; Humans; Male; Middle Aged; Prolactin; Psychotic Disorders; Schizophrenia | 1980 |
Effects of endorphins, enkephalins, certain analogues, and morphine sulfate on brain function and behavior of monkeys: a role in schizophrenia, epilepsy, and analgesia?
Topics: Analgesia; Animals; Behavior, Animal; Brain; Electroencephalography; Endorphins; Enkephalins; Epilepsy; Macaca mulatta; Morphine; Schizophrenia | 1984 |
[Neurochemistry and clinical psychiatry (author's transl)].
Topics: Adenylyl Cyclases; Bipolar Disorder; Corticotropin-Releasing Hormone; Dopamine; Endorphins; Enkephalins; Humans; Molecular Biology; Monoamine Oxidase; Norepinephrine; Schizophrenia; Serotonin | 1981 |
Endogenous opioid peptides.
Topics: Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Endorphins; Enkephalins; Humans; Rats; Schizophrenia | 1981 |
Serum antibody for somatostatin-14 and prodynorphin 209-240 in patients with obsessive-compulsive disorder, schizophrenia, Alzheimer's disease, multiple sclerosis, and advanced HIV infection.
Topics: Adult; Alzheimer Disease; Antibodies; Antibody Formation; Autoimmunity; Binding, Competitive; Enkephalins; Enzyme-Linked Immunosorbent Assay; Female; HIV Seropositivity; Humans; Male; Multiple Sclerosis; Obsessive-Compulsive Disorder; Protein Precursors; Schizophrenia; Somatostatin | 1994 |
Dopamine D1 receptor, D2 receptor, proenkephalin A and substance P gene expression in the caudate nucleus of control and schizophrenic tissue: a quantitative cellular in situ hybridisation study.
Topics: Aged; Autoradiography; Caudate Nucleus; Enkephalins; Female; Gene Expression; Humans; In Situ Hybridization; Male; Middle Aged; Oligonucleotide Probes; Organ Specificity; Phosphorus Radioisotopes; Protein Precursors; Putamen; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; Schizophrenia; Substance P | 1995 |
Identification of a missense mutation and several polymorphisms in the proenkephalin A gene of schizophrenic patients.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 8; Codon; Conserved Sequence; Enkephalins; Exons; Genetic Variation; Humans; Point Mutation; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors; Schizophrenia | 1996 |
Gly(247)-->Asp proenkephalin A mutation is rare in schizophrenia populations.
Topics: Aspartic Acid; Enkephalins; Female; Glycine; Humans; Male; Mutation; Protein Precursors; Schizophrenia | 1997 |
Prodynorphin and kappa opioid receptor mRNA expression in the cingulate and prefrontal cortices of subjects diagnosed with schizophrenia or affective disorders.
Topics: Adult; Age Factors; Amphetamine-Related Disorders; Bipolar Disorder; Depressive Disorder, Major; Enkephalins; Female; Functional Laterality; Humans; In Situ Hybridization; Male; Marijuana Abuse; Middle Aged; Protein Precursors; Receptors, Opioid, kappa; RNA, Messenger; Schizophrenia; Sex Factors; Suicide | 2001 |
Subjects with major depression or bipolar disorder show reduction of prodynorphin mRNA expression in discrete nuclei of the amygdaloid complex.
Topics: Adult; Affect; Aged; Amygdala; Bipolar Disorder; Depressive Disorder, Major; Enkephalins; Female; Gene Expression Profiling; Hippocampus; Humans; In Situ Hybridization; Male; Middle Aged; Nerve Tissue Proteins; Protein Precursors; RNA, Messenger; Schizophrenia | 2002 |
Behavioral neurochemistry: neuroregulators and behavioral states.
Topics: Animals; Behavior; Cell Communication; Depression; Endorphins; Enkephalins; Hormones; Humans; Mental Disorders; Nervous System Physiological Phenomena; Neurons; Neurotransmitter Agents; Schizophrenia; Synapses | 1978 |
Brain amines and peptides--their relevance to psychiatry.
Topics: Amines; Animals; Behavior, Animal; Brain; Depression; Dopamine; Endorphins; Enkephalins; Humans; Mental Disorders; Neurons; Neurotransmitter Agents; Peptides; Schizophrenia | 1979 |
Enkephalins: the search for a functional role.
Topics: Bipolar Disorder; Endorphins; Enkephalins; Humans; Naloxone; Nociceptors; Pain; Schizophrenia | 1978 |
Rapid inactivation of enkephalin-like material by C.S.F. in chronic schizophrenia.
Topics: Adolescent; Adult; Chronic Disease; Endorphins; Enkephalins; Friedreich Ataxia; Humans; Middle Aged; Schizophrenia | 1978 |
Schizophrenia: Reconciliation of the dopamine, prostaglandin, and opioid concepts and the role of the pineal.
Topics: Allergens; Dopamine; Endorphins; Enkephalins; Humans; Hypersensitivity; Melatonin; Pineal Gland; Plant Proteins; Prostaglandins E; Schizophrenia; Triticum; Zinc | 1979 |
[Opiate receptors and endogenous morphines: a new approach to the study of the brain].
Topics: Adenylyl Cyclases; Animals; Brain; Brain Chemistry; Cyclic AMP; Depression; Endorphins; Enkephalins; Haplorhini; Humans; Pituitary Gland; Rats; Receptors, Opioid; Schizophrenia | 1978 |
Some recent biochemical findings with possible therapeutic implications for schizophrenia.
Topics: Animals; Behavior, Animal; Cyclic AMP; Endorphins; Enkephalins; Humans; Prostaglandins; Rats; Renal Dialysis; Schizophrenia | 1978 |
The impact on neurology of 40 years' advances in pharmacology.
Topics: Acetylcholine; Chemical Phenomena; Chemistry; Chlorpromazine; Depression; Endorphins; Enkephalins; Humans; Nervous System Diseases; Penicillins; Schizophrenia; Sulfonamides | 1979 |
Degradation kinetics of leucine5-enkephalin by plasma samples from healthy controls and various patient populations: in vitro drug effects.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; Enkephalin, Leucine; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Migraine Disorders; Plasma; Schizophrenia; Specimen Handling; Substance-Related Disorders | 2000 |
Mesocortical neurotensin/dopamine system: is it involved in the pathogenesis of schizophrenia?
Topics: Animals; Brain Mapping; Cerebral Cortex; Dopamine; Enkephalin, Leucine; Frontal Lobe; Growth Hormone; Humans; Macaca; Male; Neurotensin; Schizophrenia; Schizophrenic Psychology; Substance P; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1991 |