enkephalin, leucine and Huntington Disease

enkephalin, leucine has been researched along with Huntington Disease in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (23.08)	18.7374
1990's	11 (21.15)	18.2507
2000's	18 (34.62)	29.6817
2010's	6 (11.54)	24.3611
2020's	5 (9.62)	2.80

Authors

Authors	Studies
Abu-Rumeileh, S; Al Shweiki, MHDR; Barba, L; Barschke, P; Gaetani, L; Halbgebauer, S; Landwehrmeyer, GB; Lewerenz, J; Ludolph, AC; Oeckl, P; Otto, M; Paolini Paoletti, F; Parnetti, L; Steinacker, P	1
Chen, H; Chen, L; Chen, XY; Xue, Y	1
Al Shweiki, MR; Anderl-Straub, S; Barschke, P; Bernhard Landwehrmeyer, G; Halbgebauer, S; Lewerenz, J; Ludolph, AC; Oeckl, P; Otto, M; Pachollek, A; Steinacker, P	1
Abujrais, S; Bergquist, J; Burman, J; Constantinescu, R; Kneider, M; Landtblom, AM; Niemela, V; Nyholm, D; Paucar, M; Shevchenko, G; Sundblom, J; Svenningsson, P	1
Bang, J; Ross, CA	1
Bissonnette, S; Drolet, G; Hébert, SS; Samadi, P; Vaillancourt, M	1
Gasparini, F; Gomez-Mancilla, B; Gulya, K; Gulyás, B; Halldin, C; Jia, Z; Maguire, RP; Schumacher, M; Sovago, J; Szigeti, C	1
Angus, S; Bennett, CF; Cheng, SH; Hayden, MR; Hung, GH; Sardi, PS; Shihabuddin, LS; Stanek, LM; Yang, W	1
Aebischer, P; Déglon, N; Gokce, O; Kuhn, A; Luthi-Carter, R; Perrin, V; Régulier, E; Runne, H; Sick, B; Zala, D	1
Allen, KL; Faull, RL; Glass, M; Waldvogel, HJ	1
Blum, D; Ledent, C; Mievis, S	1
Bissada, N; Davis, NG; Doty, C; Drisdel, RC; Franciosi, S; Green, WN; Hayden, MR; Henkelman, RM; Hines, R; Huang, K; Lerch, JP; Milnerwood, AJ; Raymond, LA; Sanders, SS; Singaraja, RR; Vaid, K; Wan, J; Young, FB	1
Bhattacharyya, NP; Datta, M	1
Chesselet, MF; Li, H; Li, XJ; Menalled, LB; Olivieri, M; Sison, JD; Wu, Y; Zeitlin, S	1
Bantubungi, K; Blum, D; d'Alcantara, P; Galas, MC; Gall, D; Schiffmann, SN	1
Del Mar, N; Goldowitz, D; Meade, C; Reiner, A; Sun, Z	1
Reiner, A	1
Alberch, J; Bosch, M; Canals, JM; Ernfors, P; Martín-Ibañez, R; Mengod, G; Muñoz, MT; Pineda, JR; Torres-Peraza, JF	1
Augood, SJ; Cantuti-Castelvetri, I; Cha, JH; Farrell, LA; Keller-McGandy, CE; Menon, AS; Sadri-Vakili, G; Standaert, DG; Yohrling, GJ	1
Ryan, AB; Scrable, H; Zeitlin, SO	1
Benn, CL; Cha, JH; Deng, Y; Farrell, LA; Graham, R; Hayden, MR; Slow, EJ	1
Benraiss, A; Chmielnicki, E; Cho, SR; Economides, A; Goldman, SA; Samdani, A	1
An, JJ; Gharami, K; Tonegawa, S; Xie, Y; Xu, B	1
Arregui, A; Clement-Jones, V; Emson, PC; Rossor, M; Sandberg, BE	1
Bouras, C; Constantinidis, J; Richard, J	1
Aizawa, H; Bird, E; DiFiglia, M; Ge, P; Penney, J; Sapp, E; Vonsattel, JP; Young, AB	1
Cox, C; Gilmore, J; Maguire-Zeiss, KA; Richfield, EK; Voorn, P	1
Maguire-Zeiss, KA; Richfield, EK; Vonkeman, HE; Voorn, P	1
Augood, SJ; Emson, PC; Faull, RL; Love, DR	1
Chen, Q; Reiner, A	1
Cicchetti, F; Hayden, MR; Nasir, J; O'Kusky, JR; Parent, A	1
Bordelon, YM; Chesselet, MF	1
Carpenter, E; Chesselet, MF; Koppel, A; MacKenzie, L; Menalled, L; Zanjani, H; Zeitlin, S	1
Figueredo-Cardenas, G; Fusco, F; Meade, CA; Nowak, TS; Pulsinelli, WA; Reiner, A	1
Akerund, P; Alberch, J; Arenas, E; Canudas, AM; Pérez-Navarro, E	1
Barami, K; Hutchins, KD; Lyman, WD	1
Alberch, J; Arenas, E; Marco, S; Pérez-Navarro, E; Tolosa, E	1
Deng, YP; MacDonald, ME; Reiner, A; Richfield, EK; Sun, Z; Vonsattel, JP	1
Calne, DB; Chase, TN; Eisler, T; Nutt, JG; Rosin, AJ	1
Kanazawa, I	1
Albin, RL; Anderson, KD; Balfour, R; Dure, LS; Handelin, B; Penney, JB; Reiner, A; Whetsell, WO; Young, AB	1
Albin, RL; Chesselet, MF; Penney, JB; Qin, Y; Young, AB	1
Tan, MX	1
Hunt, SP; Peck, R; Reynolds, GP; Rossor, M; Waters, CM	1
Albin, RL; Anderson, KD; D'Amato, CJ; Penney, JB; Reiner, A; Young, AB	1
Iadarola, MJ; Mouradian, MM	1
Brownstein, MJ; Dawbarn, D; Emson, PC; Hunt, SP; Waters, CM; Zamir, N	1
Gerstenbrand, F; Poewe, W	1
Landis, DM; Marshall, PE; Zalneraitis, EL	1
Albano, C; Loeb, C; Serrati, C	1
Anderson, KD; Chen, Q; Figueredo-Cardenas, G; Reiner, A; Veenman, CL	1
Beal, MF; Burd, GD; Landis, DM; Marshall, PE; Martin, JB	1

Reviews

3 review(s) available for enkephalin, leucine and Huntington Disease

Article	Year
The globus pallidus as a target for neuropeptides and endocannabinoids participating in central activities. Peptides, 2020, Volume: 124 Topics: Animals; Endocannabinoids; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Neuropeptides; Parkinson Disease; Substance P	2020
Putative peptide neurotransmitters in human neuropathology: a review of topography and clinical implications. Clinical neuropathology, 1983, Volume: 2, Issue:2 Topics: Alzheimer Disease; Brain Mapping; Central Nervous System Diseases; Cholecystokinin; Enkephalins; Humans; Huntington Disease; Limbic System; Nerve Tissue Proteins; Neurotransmitter Agents; Parkinson Disease; Schizophrenia; Substance P; Substance-Related Disorders	1983
[Peptide neurotransmitters and extrapyramidal disorders]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1985, Volume: 18, Issue:4 Topics: Animals; Basal Ganglia Diseases; Enkephalins; Humans; Huntington Disease; MSH Release-Inhibiting Hormone; Parkinson Disease; Substance P	1985

Trials

1 trial(s) available for enkephalin, leucine and Huntington Disease

Article	Year
Effect of an opiate antagonist on movement disorders. Archives of neurology, 1978, Volume: 35, Issue:12 Topics: Adult; Aged; Clinical Trials as Topic; Enkephalins; Humans; Huntington Disease; Middle Aged; Naloxone; Naltrexone; Parkinson Disease	1978

Other Studies

48 other study(ies) available for enkephalin, leucine and Huntington Disease

Article	Year
Cerebrospinal fluid levels of proenkephalin and prodynorphin are differentially altered in Huntington's and Parkinson's disease. Journal of neurology, 2022, Volume: 269, Issue:9 Topics: Biomarkers; Chromatography, Liquid; Dopamine; Enkephalins; Humans; Huntington Disease; Parkinson Disease; Protein Precursors; Tandem Mass Spectrometry	2022
Cerebrospinal Fluid Levels of Prodynorphin-Derived Peptides are Decreased in Huntington's Disease. Movement disorders : official journal of the Movement Disorder Society, 2021, Volume: 36, Issue:2 Topics: Corpus Striatum; Enkephalins; Humans; Huntingtin Protein; Huntington Disease; Neurofilament Proteins; Peptides; Protein Precursors	2021
Proenkephalin Decreases in Cerebrospinal Fluid with Symptom Progression of Huntington's Disease. Movement disorders : official journal of the Movement Disorder Society, 2021, Volume: 36, Issue:2 Topics: Biomarkers; Disease Progression; Enkephalins; Humans; Huntington Disease; Neurons; Protein Precursors; Proteomics	2021
Cerebrospinal Fluid Markers of Medium Spiny Neuron Injury in Huntington's Disease. Movement disorders : official journal of the Movement Disorder Society, 2021, Volume: 36, Issue:2 Topics: Corpus Striatum; Enkephalins; Humans; Huntington Disease; Neurons; Peptides; Protein Precursors	2021
Striatal pre-enkephalin overexpression improves Huntington's disease symptoms in the R6/2 mouse model of Huntington's disease. PloS one, 2013, Volume: 8, Issue:9 Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Enkephalins; Female; Gene Expression Regulation; Genetic Vectors; Globus Pallidus; Green Fluorescent Proteins; Huntingtin Protein; Huntington Disease; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Receptors, Opioid; RNA, Messenger; Substantia Nigra	2013
Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P immunoreactivity in Huntington's disease: a preliminary investigation in the postmortem human brain. Brain structure & function, 2015, Volume: 220, Issue:5 Topics: Aged; Autopsy; Brain; Enkephalins; Female; Humans; Huntington Disease; Male; Middle Aged; Positron-Emission Tomography; Receptor, Metabotropic Glutamate 5; Substance P	2015
Antisense oligonucleotide-mediated correction of transcriptional dysregulation is correlated with behavioral benefits in the YAC128 mouse model of Huntington's disease. Journal of Huntington's disease, 2013, Volume: 2, Issue:2 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Gene Expression Regulation; Huntingtin Protein; Huntington Disease; Hypoxanthine Phosphoribosyltransferase; Infusions, Intraventricular; Mice; Motor Skills; Neostriatum; Nerve Tissue Proteins; Nuclear Proteins; Oligonucleotides, Antisense; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Receptors, Dopamine D1; Receptors, Dopamine D2	2013
Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-24, Volume: 28, Issue:39 Topics: Animals; Corpus Striatum; Disease Models, Animal; Embryo, Mammalian; Enkephalins; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Huntington Disease; Lentivirus; Microarray Analysis; Mutation; Neurons; Peptides; Phosphoproteins; Protein Precursors; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; RGS Proteins; Transfection	2008
Cannabinoid (CB(1)), GABA(A) and GABA(B) receptor subunit changes in the globus pallidus in Huntington's disease. Journal of chemical neuroanatomy, 2009, Volume: 37, Issue:4 Topics: Aged; Aged, 80 and over; Brain Mapping; Cannabinoid Receptor Modulators; Down-Regulation; Enkephalins; Female; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Huntington Disease; Immunohistochemistry; Male; Microscopy, Confocal; Middle Aged; Nerve Degeneration; Neuronal Plasticity; Neurons; Receptor, Cannabinoid, CB1; Receptors, GABA-A; Receptors, GABA-B; Substance P; Up-Regulation	2009
A2A receptor knockout worsens survival and motor behaviour in a transgenic mouse model of Huntington's disease. Neurobiology of disease, 2011, Volume: 41, Issue:2 Topics: Animals; Enkephalins; Female; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Movement Disorders; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Receptor, Adenosine A2A; Survival Rate	2011
Altered palmitoylation and neuropathological deficits in mice lacking HIP14. Human molecular genetics, 2011, Oct-15, Volume: 20, Issue:20 Topics: Acyltransferases; Animals; Cell Death; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Huntington Disease; Lipoylation; Mice; Mice, Knockout; Motor Activity; Mutant Proteins; Nerve Tissue Proteins; Neurons; Serotonin Plasma Membrane Transport Proteins; Synapses	2011
Regulation of RE1 protein silencing transcription factor (REST) expression by HIP1 protein interactor (HIPPI). The Journal of biological chemistry, 2011, Sep-30, Volume: 286, Issue:39 Topics: Adaptor Proteins, Signal Transducing; Animals; Brain-Derived Neurotrophic Factor; Down-Regulation; Enkephalins; HEK293 Cells; HeLa Cells; Humans; Huntington Disease; Mice; Models, Biological; Protein Precursors; Repressor Proteins; Response Elements; Transcription, Genetic	2011
Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Sep-15, Volume: 22, Issue:18 Topics: Animals; Behavior, Animal; Cell Count; Cell Nucleus; Corpus Striatum; Disease Models, Animal; Disease Progression; Enkephalins; Female; Grooming; Huntingtin Protein; Huntington Disease; Inclusion Bodies; Macromolecular Substances; Male; Mice; Mice, Mutant Strains; Motor Activity; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Organ Specificity; Phenotype; Receptors, Opioid, mu; RNA, Messenger; Trinucleotide Repeat Expansion	2002
The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Oct-15, Volume: 22, Issue:20 Topics: Adenosine; Animals; Behavior, Animal; Binding, Competitive; Body Weight; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dystonia; Enkephalins; Hindlimb; Huntington Disease; In Vitro Techniques; Male; Mitochondria; Motor Activity; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred Lew; Reproducibility of Results; RNA, Messenger; Succinate Dehydrogenase; Synaptic Transmission; Treatment Outcome	2002
Differential changes in striatal projection neurons in R6/2 transgenic mice for Huntington's disease. Neurobiology of disease, 2002, Volume: 11, Issue:3 Topics: Age Factors; Animals; Autoradiography; Corpus Striatum; Disease Models, Animal; Enkephalins; Gene Expression; Genotype; Globus Pallidus; Huntington Disease; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Transgenic; Neural Pathways; Neurons; Nucleus Accumbens; Protein Precursors; RNA, Messenger; Substance P; Substantia Nigra; Tachykinins	2002
Can lesions of GPe correct HD deficits? Experimental neurology, 2004, Volume: 186, Issue:1 Topics: Animals; Disease Models, Animal; Enkephalins; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Huntington Disease; Substance P	2004
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-01, Volume: 24, Issue:35 Topics: Age of Onset; Animals; Ataxia; Brain-Derived Neurotrophic Factor; Cell Death; Cell Line, Transformed; Chorea; Corpus Striatum; Crosses, Genetic; Endocytosis; Enkephalins; Gene Expression Regulation; Huntingtin Protein; Huntington Disease; Mice; Mice, Knockout; Mice, Transgenic; Movement Disorders; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phenotype; Stem Cells; Transfection; Trinucleotide Repeats	2004
Huntingtin inclusions do not down-regulate specific genes in the R6/2 Huntington's disease mouse. The European journal of neuroscience, 2006, Volume: 23, Issue:12 Topics: Animals; Disease Models, Animal; Down-Regulation; Enkephalins; Gene Expression Regulation; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; In Situ Hybridization; Intranuclear Inclusion Bodies; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Protein Precursors; Receptors, Dopamine D2; Somatostatin	2006
Genetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesis. Neurobiology of disease, 2006, Volume: 24, Issue:2 Topics: Alleles; Animals; Brain; Disease Models, Animal; Enkephalins; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Huntingtin Protein; Huntington Disease; Intranuclear Inclusion Bodies; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Protein Precursors; RNA, Messenger; Tumor Suppressor Protein p53; Up-Regulation	2006
Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease. Neuroscience, 2007, Jun-29, Volume: 147, Issue:2 Topics: Animals; Autoradiography; Blotting, Western; Chromosomes, Artificial, Yeast; Enkephalins; Humans; Huntington Disease; In Situ Hybridization; Mice; Mice, Transgenic; Protein Precursors; Receptors, AMPA; Receptors, Dopamine; Receptors, GABA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; RNA, Messenger; Subcellular Fractions	2007
Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease. The Journal of clinical investigation, 2007, Volume: 117, Issue:10 Topics: Adenoviridae; Animals; Brain-Derived Neurotrophic Factor; Carrier Proteins; Disease Models, Animal; Disease Progression; Enkephalins; Globus Pallidus; Huntington Disease; Mice; Mice, Transgenic; Mitosis; Neostriatum; Neurons; Regeneration; Substance P; Tubulin	2007
Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice. Journal of neurochemistry, 2008, Volume: 105, Issue:2 Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Gene Expression Regulation; Huntingtin Protein; Huntington Disease; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Prosencephalon	2008
Regional distribution of methionine-enkephalin and substance P-like immunoreactivity in normal human brain and in Huntington's disease. Brain research, 1980, Oct-13, Volume: 199, Issue:1 Topics: Animals; Brain; Chromatography, High Pressure Liquid; Endorphins; Enkephalins; Humans; Huntington Disease; Mice; Middle Aged; Radioimmunoassay; Substance P	1980
Evidence for a preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis. Neuroscience, 1995, Volume: 64, Issue:2 Topics: Aged; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Image Processing, Computer-Assisted; Immunochemistry; Microscopy; Middle Aged; Substance P	1995
Reduced expression of preproenkephalin in striatal neurons from Huntington's disease patients. Annals of neurology, 1995, Volume: 37, Issue:3 Topics: Adult; Aged; Blotting, Northern; Enkephalins; Female; Gene Expression Regulation; Humans; Huntington Disease; In Situ Hybridization; Male; Middle Aged; Neostriatum; Oligonucleotide Probes; Protein Precursors; RNA, Messenger; Sensitivity and Specificity	1995
Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients. Annals of neurology, 1995, Volume: 38, Issue:6 Topics: Adult; Aged; Blotting, Northern; Calbindin 1; Calbindins; Enkephalins; Female; Histocytochemistry; Humans; Huntington Disease; In Situ Hybridization; Male; Middle Aged; Neostriatum; Nerve Tissue Proteins; Neurons; Oligonucleotide Probes; Protein Precursors; RNA, Messenger; S100 Calcium Binding Protein G; Sensitivity and Specificity; Tachykinins	1995
Reduction in enkephalin and substance P messenger RNA in the striatum of early grade Huntington's disease: a detailed cellular in situ hybridization study. Neuroscience, 1996, Volume: 72, Issue:4 Topics: Aged; Aged, 80 and over; Enkephalins; Female; Gene Expression; Humans; Huntington Disease; Image Processing, Computer-Assisted; In Situ Hybridization; Male; Middle Aged; Neostriatum; RNA, Messenger; Substance P	1996
Cellular distribution of the NMDA receptor NR2A/2B subunits in the rat striatum. Brain research, 1996, Dec-16, Volume: 743, Issue:1-2 Topics: Acetylcholine; Animals; Calbindins; Corpus Striatum; Enkephalins; Huntington Disease; Interneurons; Male; Nerve Tissue Proteins; Neurons; Parvalbumins; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S100 Calcium Binding Protein G; Somatostatin; Substance P	1996
Neuronal degeneration in the basal ganglia and loss of pallido-subthalamic synapses in mice with targeted disruption of the Huntington's disease gene. Brain research, 1999, Feb-13, Volume: 818, Issue:2 Topics: Afferent Pathways; Animals; Basal Ganglia; Enkephalins; Gene Targeting; Globus Pallidus; Heterozygote; Huntington Disease; Immunohistochemistry; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroglia; Neurons; Substance P; Synapses; Thalamic Nuclei	1999
Early effects of intrastriatal injections of quinolinic acid on microtubule-associated protein-2 and neuropeptides in rat basal ganglia. Neuroscience, 1999, Volume: 93, Issue:3 Topics: Animals; Basal Ganglia; Corpus Striatum; Cytoskeleton; Disease Models, Animal; DNA Damage; Efferent Pathways; Enkephalins; Excitatory Amino Acid Agonists; Globus Pallidus; Huntington Disease; Injections; Male; Mice; Mice, Neurologic Mutants; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P	1999
Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease. Experimental neurology, 2000, Volume: 162, Issue:2 Topics: Animals; Biomarkers; Calbindins; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; DNA Damage; Enkephalins; Female; Glutamate Decarboxylase; Homozygote; Huntingtin Protein; Huntington Disease; Isoenzymes; Male; Mice; Mice, Knockout; Mice, Neurologic Mutants; Motor Activity; Nerve Tissue Proteins; Neurons; Nuclear Proteins; RNA, Messenger; S100 Calcium Binding Protein G; Substance P; Trinucleotide Repeats	2000
Transient global ischemia in rats yields striatal projection neuron and interneuron loss resembling that in Huntington's disease. Experimental neurology, 2000, Volume: 166, Issue:2 Topics: Animals; Cell Survival; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Enkephalins; Huntington Disease; Image Processing, Computer-Assisted; Interneurons; Ischemic Attack, Transient; Male; NADPH Dehydrogenase; Nerve Fibers; Neural Pathways; Rats; Rats, Sprague-Dawley; Rats, Wistar; Somatostatin; Substance P	2000
Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease. Journal of neurochemistry, 2000, Volume: 75, Issue:5 Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Death; Cell Line; Cell Transplantation; Corpus Striatum; Disease Models, Animal; Enkephalins; Fibroblasts; Glutamate Decarboxylase; Huntington Disease; Isoenzymes; Male; Nerve Growth Factors; Neurons; Neurotrophin 3; Phosphorylation; Protein Precursors; Quinolinic Acid; Rats; Rats, Inbred F344; Receptor, trkB; Tachykinins	2000
Neurotransmitter distribution in the second trimester fetal human corpus striatum. Neurological research, 2001, Volume: 23, Issue:1 Topics: Acetylcholine; Age Factors; Brain Tissue Transplantation; Corpus Striatum; Enkephalins; Female; Fetal Tissue Transplantation; Fetus; gamma-Aminobutyric Acid; Humans; Huntington Disease; Neurons; Neuropeptide Y; Neurotransmitter Agents; Pregnancy; Pregnancy Trimester, Second; Substance P	2001
Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease. Journal of neurobiology, 2002, Volume: 50, Issue:4 Topics: Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Enkephalins; Globus Pallidus; Glutamate Decarboxylase; Huntington Disease; Isoenzymes; Male; Neostriatum; Nerve Growth Factors; Neural Pathways; Neurons; Neuroprotective Agents; Neurotoxins; Neurturin; Protein Precursors; Quinolinic Acid; Rats; Rats, Inbred F344; RNA, Messenger; Tachykinins	2002
Selective loss of striatal preprotachykinin neurons in a phenocopy of Huntington's disease. Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17, Issue:2 Topics: Aged; Cell Survival; Corpus Striatum; Enkephalins; Female; Gene Expression; Globus Pallidus; Humans; Huntington Disease; Neurologic Examination; Neurons; Phenotype; Polymerase Chain Reaction; Protein Precursors; Substance P; Tachykinins; Trinucleotide Repeats	2002
On chorea: possible neuronal mechanisms. Clinical neurology and neurosurgery, 1992, Volume: 94 Suppl Topics: Animals; Brain Mapping; Corpus Striatum; Dopamine; Enkephalins; gamma-Aminobutyric Acid; Humans; Huntington Disease; Macaca; Nerve Degeneration; Neural Pathways; Substantia Nigra	1992
Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease. Annals of neurology, 1992, Volume: 31, Issue:4 Topics: Adult; Cell Survival; Corpus Striatum; Enkephalins; Glial Fibrillary Acidic Protein; Globus Pallidus; Humans; Huntington Disease; Immunohistochemistry; Male; Neurons; Substance P; Synaptic Transmission	1992
Preproenkephalin messenger RNA-containing neurons in striatum of patients with symptomatic and presymptomatic Huntington's disease: an in situ hybridization study. Annals of neurology, 1991, Volume: 30, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoradiography; Child; Corpus Striatum; Enkephalins; Humans; Huntington Disease; Middle Aged; Neurons; Nucleic Acid Hybridization; Protein Precursors; RNA Probes; RNA, Messenger	1991
Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's chorea. Neuroscience, 1988, Volume: 25, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Basal Ganglia; Catecholamines; Cell Count; Enkephalins; Female; Humans; Huntington Disease; Immunohistochemistry; Male; Middle Aged; Parkinson Disease; Substance P; Substantia Nigra	1988
Differential loss of striatal projection neurons in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:15 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Axons; Child; Corpus Striatum; Enkephalins; Humans; Huntington Disease; Immunohistochemistry; Middle Aged; Neurons; Substance P	1988
Decrease in a proenkephalin peptide in cerebrospinal fluid in Huntington's disease and progressive supranuclear palsy. Brain research, 1989, Feb-13, Volume: 479, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Enkephalin, Methionine; Enkephalins; Humans; Huntington Disease; Middle Aged; Protein Precursors; Supranuclear Palsy, Progressive	1989
Peptides derived from prodynorphin are decreased in basal ganglia of Huntington's disease brains. Brain research, 1986, Apr-30, Volume: 372, Issue:1 Topics: Basal Ganglia; Caudate Nucleus; Dynorphins; Endorphins; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Protein Precursors; Putamen; Substantia Nigra	1986
Dopaminergic-peptidergic interactions in extrapyramidal disorders: a review of the clinical evidence. Advances in neurology, 1987, Volume: 45 Topics: Basal Ganglia; Brain; Dopamine; Enkephalins; Humans; Huntington Disease; MSH Release-Inhibiting Hormone; Neuropeptides; Parkinson Disease	1987
Immunocytochemical studies of substance P and leucine-enkephalin in Huntington's disease. Brain research, 1983, Dec-19, Volume: 289, Issue:1-2 Topics: Adolescent; Adult; Aged; Brain; Caudate Nucleus; Corpus Striatum; Enkephalin, Leucine; Globus Pallidus; Humans; Huntington Disease; Immunoenzyme Techniques; Middle Aged; Nerve Degeneration; Neural Pathways; Neurons; Putamen; Substance P; Substantia Nigra	1983
[Cerebrospinal fluid levels of leucine enkephalin and methionine enkephalin in patients with altered behavior]. Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1984, Volume: 134, Issue:1 Topics: Adult; Aged; Alzheimer Disease; Depressive Disorder; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Huntington Disease; Male; Middle Aged; Neurocognitive Disorders; Schizophrenia, Paranoid	1984
Relative survival of striatal projection neurons and interneurons after intrastriatal injection of quinolinic acid in rats. Experimental neurology, 1994, Volume: 129, Issue:1 Topics: Animals; Antibodies; Cell Survival; Choline O-Acetyltransferase; Corpus Striatum; Efferent Pathways; Enkephalin, Leucine; Enkephalin, Methionine; Globus Pallidus; Huntington Disease; Immunohistochemistry; Interneurons; Male; Microinjections; Nerve Fibers; Neurons; Neuropeptide Y; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Somatostatin	1994
Excitotoxin lesions do not mimic the alteration of somatostatin in Huntington's disease. Brain research, 1985, Dec-30, Volume: 361, Issue:1-2 Topics: Animals; Brain; Corpus Striatum; Disease Models, Animal; Enkephalin, Leucine; Humans; Huntington Disease; Ibotenic Acid; Immune Sera; Immunoassay; Kainic Acid; Male; Neurons; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Tissue Distribution	1985