enkephalin, leucine and Heroin Abuse

enkephalin, leucine has been researched along with Heroin Abuse in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's4 (21.05)18.2507
2000's4 (21.05)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blanken, P; Butelman, ER; Kreek, MJ; Ott, J; Randesi, M; van den Brink, W; van Ree, JM; Yuferov, V1
Anderson, SA; Bannon, M; Fagergren, P; Hurd, YL; Keller, E; Michaelides, M; Neumaier, JF; Ren, Y; Thanos, PK; Volkow, ND; Wang, GJ; Zarnegar, P1
Crawford, EF; George, O; Koob, GF; Park, PE; Schlosburg, JE; Vendruscolo, LF; Whitfield, TW1
Saadat, I; Saadat, M; Saify, K1
Clarke, TK; Krause, K; Li, T; Schumann, G1
Chai, ZQ; Lai, JH; Li, SB; Wei, SG; Xue, HX; Zhu, YS1
Ambrose-Lanci, L; Berrettini, WH; Clarke, TK; Dackis, CA; Ferraro, TN; Kampman, KM; Lohoff, FW; O'Brien, CP; Oslin, DW; Pettinati, HM1
Ellgren, M; Hurd, YL; Spano, MS; Wang, X1
Herz, A1
Brambilla, F; Casanueva, F; Lovati, C; Madeddu, A; Martinez-Campos, A; Müller, EE; Peñalva, A1
Barturen, F; Gabilondo, AM; García-Sevilla, JA; Meana, JJ; Sastre, M1
DeMontis, MG; Dworkin, SI; Kim, SA; Martin, TJ; Sizemore, GM; Smith, JE1
Blake, H; Comings, DE; Dietz, G; Gade-Andavolu, R; Johnson, P; Legro, RS; MacMurray, JP; Saucier, G; Verde, R1
Höllt, V; Kraus, J; Mayer, P; Rauch, E; Wöltje, M; Zimprich, A1
Besser, GM; Clement-Jones, V; Lowry, PJ; McLoughlin, L; Rees, LH; Wen, HL1
Kalat, JW1
Janković, BD1
Kato, Y2

Reviews

2 review(s) available for enkephalin, leucine and Heroin Abuse

ArticleYear
The neuro-immune network. Some recent developments.
    Recenti progressi in medicina, 1992, Volume: 83, Issue:2

    Topics: Animals; Autoantibodies; Brain; Enkephalins; Heroin Dependence; HIV Infections; Humans; Hypersensitivity, Delayed; Immune System; Lithium; Magnetics; Nervous System Diseases; Neuroimmunomodulation

1992
[Methionine-enkephalin (Met-Enk) and leucine-enkephalin (Leu-Enk)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: Adrenal Gland Neoplasms; Alcoholism; Cerebral Infarction; Craniocerebral Trauma; Diagnostic Techniques, Endocrine; Enkephalin, Leucine; Enkephalin, Methionine; Heroin Dependence; Humans; Kidney Failure, Chronic; Pheochromocytoma; Radioimmunoassay; Reference Values; Specimen Handling

2005

Trials

1 trial(s) available for enkephalin, leucine and Heroin Abuse

ArticleYear
Lack of tolerance in heroin-addicts to the neuroendocrine effects of an enkephalin analogue.
    Life sciences, 1981, Aug-03, Volume: 29, Issue:5

    Topics: Adult; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Tolerance; Endorphins; Enkephalins; Follicle Stimulating Hormone; Growth Hormone; Heroin Dependence; Hormones; Humans; Luteinizing Hormone; Male; Prolactin; Thyrotropin; Time Factors

1981

Other Studies

16 other study(ies) available for enkephalin, leucine and Heroin Abuse

ArticleYear
Association of variants of prodynorphin promoter 68-bp repeats in caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use.
    Neuroscience letters, 2019, 06-21, Volume: 704

    Topics: Adult; Case-Control Studies; Enkephalins; Female; Genetic Association Studies; Genotype; Heroin Dependence; Humans; Male; Middle Aged; Opioid-Related Disorders; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors; White People

2019
Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:12

    Topics: Adult; Amygdala; Animals; Clozapine; Corticosterone; Depressive Disorder, Major; Designer Drugs; Enkephalins; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; GTP-Binding Protein alpha Subunits, Gi-Go; Heroin Dependence; Humans; Hungary; Limbic System; Male; Middle Aged; Neuroimaging; Neurons; Positron-Emission Tomography; Protein Precursors; Radiopharmaceuticals; Rats; Rats, Long-Evans; Recombinant Fusion Proteins; RNA, Messenger; United States

2013
Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Dec-04, Volume: 33, Issue:49

    Topics: Animals; Anxiety; Catheterization; Conditioning, Operant; Enkephalins; Heroin Dependence; Immunohistochemistry; Male; Motivation; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reinforcement Schedule; Self Administration; Substance Withdrawal Syndrome

2013
Association between VNTR polymorphism in promoter region of prodynorphin (PDYN) gene and heroin dependence.
    Psychiatry research, 2014, Nov-30, Volume: 219, Issue:3

    Topics: Alleles; Case-Control Studies; Enkephalin, Leucine; Enkephalins; Genetic Predisposition to Disease; Genotype; Heroin Dependence; Humans; Male; Minisatellite Repeats; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors

2014
An association of prodynorphin polymorphisms and opioid dependence in females in a Chinese population.
    Addiction biology, 2009, Volume: 14, Issue:3

    Topics: 3' Untranslated Regions; Adult; Alleles; China; Enkephalins; Female; Gene Frequency; Genotype; Haplotypes; Heroin Dependence; Humans; Linkage Disequilibrium; Male; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein Precursors; RNA, Messenger; Sex Factors

2009
Association between heroin dependence and prodynorphin gene polymorphisms.
    Brain research bulletin, 2011, May-30, Volume: 85, Issue:3-4

    Topics: Adult; Chi-Square Distribution; Enkephalins; Female; Genetic Predisposition to Disease; Genotype; Heroin Dependence; Humans; Male; Minisatellite Repeats; Polymorphism, Single Nucleotide; Protein Precursors

2011
Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.
    Genes, brain, and behavior, 2012, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Alleles; Behavior, Addictive; Black or African American; Cocaine-Related Disorders; Enkephalins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Heroin Dependence; Humans; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Precursors; Sex Factors; White People

2012
Prenatal cannabis exposure increases heroin seeking with allostatic changes in limbic enkephalin systems in adulthood.
    Biological psychiatry, 2007, Feb-15, Volume: 61, Issue:4

    Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Cannabis; Conditioning, Operant; Dynorphins; Enkephalins; Female; Guanosine 5'-O-(3-Thiotriphosphate); Heroin Dependence; In Situ Hybridization; Limbic System; Pregnancy; Prenatal Exposure Delayed Effects; Protein Binding; Protein Precursors; Rats; Rats, Long-Evans; Reaction Time

2007
Role of endorphins in addiction.
    Modern problems of pharmacopsychiatry, 1981, Volume: 17

    Topics: Alcoholism; Animals; beta-Endorphin; Brain; Corpus Striatum; Endorphins; Enkephalins; Heroin Dependence; Humans; Morphine Dependence; Opioid-Related Disorders; Pituitary Gland; Rats; Receptors, Opioid

1981
mu-Opioid receptor and alpha 2-adrenoceptor agonist binding sites in the postmortem brain of heroin addicts.
    Psychopharmacology, 1994, Volume: 115, Issue:1-2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Amino Acid Sequence; Analgesics; Brain Chemistry; Chronic Disease; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Heroin Dependence; Humans; Male; Molecular Sequence Data; Radioligand Assay; Receptors, Opioid, mu

1994
Effects of beta-funaltrexamine on dose-effect curves for heroin self-administration in rats: comparison with alteration of [3H]DAMGO binding to rat brain sections.
    Drug and alcohol dependence, 1998, Oct-01, Volume: 52, Issue:2

    Topics: Analgesics, Opioid; Animals; Brain; Caudate Nucleus; Cocaine; Culture Techniques; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Heroin; Heroin Dependence; Motivation; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Radioligand Assay; Rats; Receptors, Opioid, mu; Self Administration

1998
The proenkephalin gene (PENK) and opioid dependence.
    Neuroreport, 1999, Apr-06, Volume: 10, Issue:5

    Topics: Adult; Alcohol-Related Disorders; Alleles; Amphetamine-Related Disorders; Cocaine-Related Disorders; Dinucleotide Repeats; Enkephalins; Female; Gene Frequency; Heroin Dependence; Humans; Male; Protein Precursors; Substance-Related Disorders; White People

1999
An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression.
    Journal of neurochemistry, 2000, Volume: 74, Issue:2

    Topics: Alleles; Base Sequence; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; DNA; Enkephalins; Gene Expression; Gene Frequency; Genetic Variation; Heroin Dependence; Humans; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Precursors; Reference Values; Tandem Repeat Sequences; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection

2000
Acupuncture in heroin addicts; changes in Met-enkephalin and beta-endorphin in blood and cerebrospinal fluid.
    Lancet (London, England), 1979, Aug-25, Volume: 2, Issue:8139

    Topics: Acupuncture Therapy; Adrenocorticotropic Hormone; Adult; Antigens; beta-Lipotropin; Endorphins; Enkephalins; Heroin Dependence; Humans; Hydrocortisone; Male; Methionine; Middle Aged; Substance Withdrawal Syndrome

1979
Speculations on similarities between autism and opiate addiction.
    Journal of autism and childhood schizophrenia, 1978, Volume: 8, Issue:4

    Topics: Autistic Disorder; Endorphins; Enkephalins; Heroin Dependence; Humans; Morphine; Naloxone; Social Behavior

1978
[Clinical significance of serum enkephalin analysis in pituitary function tests].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: Cushing Syndrome; Enkephalin, Leucine; Enkephalin, Methionine; Female; Heroin Dependence; Humans; Hypopituitarism; Infant, Newborn; Male; Menstrual Cycle; Nelson Syndrome; Pituitary Function Tests; Pregnancy; Radioimmunoassay; Radioligand Assay; Reference Values

1989