enkephalin, leucine has been researched along with Genetic Predisposition in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 17 (54.84) | 29.6817 |
| 2010's | 13 (41.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, WG; Luo, RQ; Ma, M; Wang, CW | 1 |
| Saadat, I; Saadat, M; Saify, K | 1 |
| Kang, HC; Ouyang, TH; Zhang, N; Zhou, Q; Zhu, SQ | 1 |
| Bakalkin, G; Biernacka, JM; Geske, JR; Heit, JA; Karpyak, VM; Preuss, UW; Winham, SJ; Zill, P | 1 |
| Ho, A; Ji, F; Kreek, MJ; Levran, O; Morgello, S; Nielsen, DA; Ott, J; Shi, R; Yuferov, V | 1 |
| Crespel, A; Lambercy, C; Malafosse, A; Perroud, N; Salzmann, A | 1 |
| Agrawal, A; Gordon, SD; Hansell, NK; Heath, AC; Lind, PA; Madden, PA; Martin, NG; Montgomery, GW; Morley, KI; Pergadia, ML; Todd, RD; Whitfield, JB | 1 |
| Angermeyer, MC; Bickel, H; Bilkei-Gorzó, A; Daerr, M; Dichgans, M; Fuchs, A; Jessen, F; Kaduszkiewicz, H; Kölsch, H; Maier, W; Mösch, E; Pentzek, M; Riedel-Heller, SG; Toliat, MR; van den Bussche, H; Wagner, M; Werle, J; Weyerer, S; Wiese, B | 1 |
| Chai, ZQ; Lai, JH; Li, SB; Wei, SG; Xue, HX; Zhu, YS | 1 |
| Alkass, K; Bakalkin, G; Bazov, I; Druid, H; Harper, C; Nyberg, F; Sheedy, D; Taqi, MM; Watanabe, H; Wentzel, P; Yakovleva, T | 1 |
| Ferrell, RE; Flory, JD; Hurd, Y; Manuck, SB; Pytte, CL | 1 |
| Chan, S; Coppola, G; Fogel, BL; Geschwind, DH; Huang, A; Klein, E; Lane, J; Lee, JY; Mamah, C; Osborn, GE; Perlman, S; Wahnich, A | 1 |
| Čupić, B; Gabrilovac, J; Hranilovic, D; Jernej, B | 1 |
| Ambrose-Lanci, L; Berrettini, WH; Clarke, TK; Dackis, CA; Ferraro, TN; Kampman, KM; Lohoff, FW; O'Brien, CP; Oslin, DW; Pettinati, HM | 1 |
| Butelman, ER; Kreek, MJ; Yuferov, V | 1 |
| Golda, S; Korostynski, M; Przewlocki, R; Solecki, W; Szklarczyk, K | 1 |
| Abulseoud, OA; Bakalkin, G; Bazov, I; Biernacka, JM; Colby, CL; Cunningham, JM; Frye, MA; Geske, JR; Hall-Flavin, DK; Heit, JA; Karpyak, VM; Lewis, KA; Loukianova, LL; Mrazek, DA; Preuss, UW; Schneekloth, TD; Walker, DL; Winham, SJ; Zill, P | 1 |
| Biguet, NF; Colin, P; Guibert, B; Mallet, J; Sánchez-Capelo, A | 1 |
| Feng, GY; Gu, NF; He, L; He, Y; Lu, L; Tan, Z; Wu, SN; Zhang, CS | 1 |
| Geyer, MA; Kuczenski, R; Lohr, JB; Niculescu, AB; Ogden, CA; Paulus, MP; Rich, ME; Schork, NJ | 1 |
| Beadles-Bohling, AS; Wiren, KM | 1 |
| Berrettini, WH; Dahl, JP; Ferraro, TN; Kampman, KM; Lohoff, FW; O'Brien, CP; Oslin, DW; Weller, AE | 1 |
| Harano, M; Inada, T; Iwata, N; Iyo, M; Kishimoto, M; Komiyama, T; Kuroda, S; Morio, A; Morita, Y; Nomura, A; Otani, K; Ozaki, N; Sekine, Y; Sora, I; Tanaka, Y; Ujike, H; Yamada, M | 1 |
| Agrawal, A; Begleiter, H; Bierut, L; Bucholz, K; Dick, D; Edenberg, HJ; Flury-Wetherill, L; Foroud, T; Goate, A; Kuperman, S; Nurnberger, J; Porjesz, B; Schuckit, M; Tian, HJ; Tischfield, J; Xuei, X | 1 |
| Ryan, AB; Scrable, H; Zeitlin, SO | 1 |
| Abbruzzese, JL; Evans, DB; Hassan, MM; Jiao, L; Li, D; Zhu, J | 1 |
| Cirulli, ET; Goldstein, DB | 1 |
| Aguglia, U; Bianchi, A; Binelli, S; Bisulli, F; Bortoluzzi, S; Bovo, G; Coppola, G; De Falco, A; Di Bonaventura, C; Diani, E; Egeo, G; Elia, M; Ferlazzo, E; Gambardella, A; Giallonardo, AT; Gobbi, G; Mecarelli, O; Michelucci, R; Nobile, C; Sofia, V; Striano, P; Striano, S; Tinuper, P; Vettori, A | 1 |
| Höllt, V; Mayer, P | 1 |
| Aull-Watschinger, S; Baumgartner, C; Höllt, V; Stögmann, E; Zimprich, A; Zimprich, F | 1 |
| Edwards, E; Hartnick, C; Henn, FA; Lachman, HM; Papolos, DF; Ramazankhana, R; Weiner, ED | 1 |
4 review(s) available for enkephalin, leucine and Genetic Predisposition
| Article | Year |
|---|---|
Association between prodynorphin gene polymorphisms and opioid dependence susceptibility: a meta-analysis.
Topics: Asian People; Case-Control Studies; Enkephalins; Genetic Predisposition to Disease; Humans; Opioid-Related Disorders; Polymorphism, Single Nucleotide; Protein Precursors | 2019 |
Prodynorphin gene promoter polymorphism and temporal lobe epilepsy: A meta-analysis.
Topics: Case-Control Studies; Enkephalins; Epilepsy, Temporal Lobe; Family; Gene Expression; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Inheritance Patterns; Odds Ratio; Polymorphism, Genetic; Prognosis; Promoter Regions, Genetic; Protein Precursors | 2015 |
κ-opioid receptor/dynorphin system: genetic and pharmacotherapeutic implications for addiction.
Topics: Adaptation, Biological; Animals; Behavior, Addictive; Disease Models, Animal; Drug Discovery; Dynorphins; Enkephalins; Genetic Predisposition to Disease; Humans; Illicit Drugs; Narcotic Antagonists; Polymorphism, Genetic; Protein Precursors; Receptors, Opioid, kappa; Recurrence | 2012 |
Allelic and somatic variations in the endogenous opioid system of humans.
Topics: Alleles; beta-Endorphin; Enkephalins; Genetic Predisposition to Disease; Humans; Polymorphism, Genetic; Protein Precursors; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance-Related Disorders | 2001 |
27 other study(ies) available for enkephalin, leucine and Genetic Predisposition
| Article | Year |
|---|---|
Association between VNTR polymorphism in promoter region of prodynorphin (PDYN) gene and heroin dependence.
Topics: Alleles; Case-Control Studies; Enkephalin, Leucine; Enkephalins; Genetic Predisposition to Disease; Genotype; Heroin Dependence; Humans; Male; Minisatellite Repeats; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors | 2014 |
Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent.
Topics: Adult; Alcoholism; Enkephalins; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Protein Precursors; Sex Factors; White People | 2015 |
A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain.
Topics: Alcohol-Related Disorders; Black or African American; Brain; Cocaine-Related Disorders; Enkephalins; Gene Expression; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; Polymorphism, Single Nucleotide; Protein Precursors; RNA, Messenger; White People | 2009 |
Candidate genes for temporal lobe epilepsy: a replication study.
Topics: Adolescent; Adult; Apolipoproteins E; Case-Control Studies; Child; Cohort Studies; DNA Mutational Analysis; Enkephalins; Epilepsy, Temporal Lobe; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Interleukins; Polymorphism, Genetic; Protein Precursors | 2008 |
Can we identify genes for alcohol consumption in samples ascertained for heterogeneous purposes?
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Angiotensinogen; Australia; Data Collection; Enkephalins; Female; Genetic Heterogeneity; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Humans; Interviews as Topic; Linear Models; Male; Middle Aged; Protein Precursors; Receptors, Opioid, delta; Young Adult | 2009 |
Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly.
Topics: Aged; Aged, 80 and over; Cognition; Cognition Disorders; DNA Mutational Analysis; Enkephalins; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Heterozygote; Humans; Male; Memory; Memory Disorders; Minisatellite Repeats; Neuropsychological Tests; Polymorphism, Genetic; Protein Precursors; Verbal Behavior | 2009 |
Association between heroin dependence and prodynorphin gene polymorphisms.
Topics: Adult; Chi-Square Distribution; Enkephalins; Female; Genetic Predisposition to Disease; Genotype; Heroin Dependence; Humans; Male; Minisatellite Repeats; Polymorphism, Single Nucleotide; Protein Precursors | 2011 |
Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics.
Topics: 3' Untranslated Regions; Adult; Aged; Alcoholism; Alleles; CpG Islands; DNA Methylation; Enkephalins; Epigenomics; Genetic Predisposition to Disease; Genotype; Humans; Male; Polymorphism, Single Nucleotide; Prefrontal Cortex; Protein Precursors | 2011 |
Alcohol dependence, disinhibited behavior and variation in the prodynorphin gene.
Topics: Adult; Alcoholism; Diagnostic and Statistical Manual of Mental Disorders; Enkephalins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Impulsive Behavior; Inhibition, Psychological; Male; Middle Aged; Personality; Polymorphism, Genetic; Protein Precursors; Sex Factors | 2011 |
Mutations in rare ataxia genes are uncommon causes of sporadic cerebellar ataxia.
Topics: Adult; Aged; Cerebellar Ataxia; Cytoskeletal Proteins; Databases, Bibliographic; DNA Helicases; Enkephalins; Female; Genetic Predisposition to Disease; Genetic Testing; Heat-Shock Proteins; Humans; Lamin Type B; Magnetic Resonance Imaging; Male; Middle Aged; Multifunctional Enzymes; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Protein Precursors; RNA Helicases; Transglutaminases | 2012 |
Association study of genes regulating opioid system in autism.
Topics: Adolescent; Adult; Autistic Disorder; Child; Croatia; Dipeptidyl Peptidase 4; Enkephalins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Mutation; Peptide Hydrolases; Polymorphism, Single Nucleotide; Pro-Opiomelanocortin; Protein Precursors; Receptors, Opioid; Young Adult | 2012 |
Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.
Topics: Adolescent; Adult; Alleles; Behavior, Addictive; Black or African American; Cocaine-Related Disorders; Enkephalins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Heroin Dependence; Humans; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Precursors; Sex Factors; White People | 2012 |
Genotype-dependent consequences of traumatic stress in four inbred mouse strains.
Topics: Amygdala; Animals; Disease Models, Animal; Electroshock; Enkephalins; Genetic Predisposition to Disease; Genotype; Hippocampus; I-kappa B Proteins; Mice; Mice, Inbred Strains; NF-KappaB Inhibitor alpha; Phenotype; Protein Precursors; Species Specificity; Stress Disorders, Post-Traumatic; Transcription Factors | 2012 |
Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states.
Topics: Alcoholism; Enkephalins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Linkage Disequilibrium; Male; Mood Disorders; Polymorphism, Single Nucleotide; Protein Precursors; Receptors, Opioid, kappa | 2013 |
Transforming growth factor beta1 overexpression in the nigrostriatal system increases the dopaminergic deficit of MPTP mice.
Topics: Animals; Disease Models, Animal; Dopamine; Down-Regulation; Enkephalins; Gene Transfer Techniques; Genetic Predisposition to Disease; Genetic Vectors; Humans; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neural Pathways; Parkinsonian Disorders; RNA, Messenger; Substantia Nigra; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Up-Regulation | 2003 |
Polymorphism of Prodynorphin promoter is associated with schizophrenia in Chinese population.
Topics: Adult; Asian People; Enkephalins; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein Precursors; Schizophrenia | 2004 |
Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach.
Topics: Animals; Antimanic Agents; Bayes Theorem; Bipolar Disorder; Brain; Central Nervous System Stimulants; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Gene Expression Profiling; Genetic Linkage; Genetic Predisposition to Disease; Genetic Testing; Genomics; Humans; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Microarray Analysis; Nerve Tissue Proteins; Pharmacogenetics; Phosphoproteins; Protein Precursors; Substance P; Tachykinins; Valproic Acid | 2004 |
Alteration of kappa-opioid receptor system expression in distinct brain regions of a genetic model of enhanced ethanol withdrawal severity.
Topics: Alcohol Withdrawal Seizures; Analysis of Variance; Animals; Basal Ganglia; Brain; Caudate Nucleus; Central Nervous System Depressants; Disease Models, Animal; Enkephalins; Ethanol; Genetic Predisposition to Disease; Gyrus Cinguli; In Situ Hybridization; Male; Mice; Mice, Inbred Strains; Nucleus Accumbens; Olfactory Pathways; Protein Precursors; Putamen; Receptors, Opioid, kappa; RNA, Messenger; Species Specificity; Tissue Distribution | 2005 |
Confirmation of the association between a polymorphism in the promoter region of the prodynorphin gene and cocaine dependence.
Topics: Adult; Black or African American; Cocaine-Related Disorders; Enkephalins; Female; Genetic Predisposition to Disease; Humans; Male; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors | 2005 |
Genetic variant of prodynorphin gene is risk factor for methamphetamine dependence.
Topics: Adult; Amphetamine-Related Disorders; Confidence Intervals; Enkephalins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors; Repetitive Sequences, Nucleic Acid; Risk Factors | 2006 |
Association of the kappa-opioid system with alcohol dependence.
Topics: Alcoholism; Enkephalins; Genetic Predisposition to Disease; Haplotypes; Humans; Linkage Disequilibrium; Pedigree; Polymorphism, Single Nucleotide; Protein Precursors; Receptors, Opioid, kappa; Risk Factors; White People | 2006 |
Genetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesis.
Topics: Alleles; Animals; Brain; Disease Models, Animal; Enkephalins; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Huntingtin Protein; Huntington Disease; Intranuclear Inclusion Bodies; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Protein Precursors; RNA, Messenger; Tumor Suppressor Protein p53; Up-Regulation | 2006 |
K-ras mutation and p16 and preproenkephalin promoter hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking.
Topics: Adenocarcinoma; Adult; Aged; DNA Methylation; Enkephalins; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, ras; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Mutation; Pancreatic Neoplasms; Promoter Regions, Genetic; Protein Precursors; Smoking | 2007 |
In vitro assays fail to predict in vivo effects of regulatory polymorphisms.
Topics: Aged; Aged, 80 and over; Allelic Imbalance; Alzheimer Disease; Brain; Enkephalins; Female; Gene Expression; Genes, Reporter; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Male; Monoamine Oxidase; Neuropeptide Y; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors | 2007 |
Analysis of LGI1 promoter sequence, PDYN and GABBR1 polymorphisms in sporadic and familial lateral temporal lobe epilepsy.
Topics: Base Sequence; Enkephalins; Epilepsy, Temporal Lobe; Genetic Predisposition to Disease; Humans; Intracellular Signaling Peptides and Proteins; Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein Precursors; Proteins; Receptors, GABA-B | 2008 |
A functional polymorphism in the prodynorphin gene promotor is associated with temporal lobe epilepsy.
Topics: Enkephalins; Epilepsy, Temporal Lobe; Female; Genetic Predisposition to Disease; Humans; Male; Polymorphism, Genetic; Promoter Regions, Genetic; Protein Precursors; Risk Factors; Severity of Illness Index | 2002 |
Hippocampal neuropeptide Y mRNA is reduced in a strain of learned helpless resistant rats.
Topics: Amino Acid Isomerases; Animals; Association Learning; Carrier Proteins; Cerebral Cortex; Disease Susceptibility; Enkephalins; Escape Reaction; Gene Expression; Genetic Predisposition to Disease; Helplessness, Learned; Hippocampus; Malate Dehydrogenase; Male; Neuropeptide Y; Peptidylprolyl Isomerase; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Somatostatin | 1992 |