enkephalin, leucine has been researched along with Chronic Pain in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Bansal, N; Fonseca, A; Gillis, J; Gulati, A; Horine, SV; Kuppalli, S; Mendelson, A; Southerland, WA | 1 |
| Liu, X; Ma, M; Wang, K; Wang, R; Wang, Y; Wei, S; Zhang, X; Zhao, L; Zhou, J | 1 |
| Dimitrov, E; Paretkar, T | 1 |
| Bilsky, EJ; Cain, JP; Hruby, VJ; Hu, J; Kumirov, VK; Lee, YS; Podolsky, AT; Sandweiss, A; Vanderah, TW; Vardanyan, RS | 1 |
| Carlson, CR; Danaher, RJ; Ma, F; Miller, CS; Wang, C; Westlund, KN; Yoder, WE | 1 |
| García Gutiérrez, MS; Maldonado, R; Manzanares, J; Negrete, R | 1 |
| Fournié-Zaluski, MC; Roques, BP; Wurm, M | 1 |
| Fink, DJ; Mata, M; Wolfe, D | 1 |
| An, K; Gao, F; Jin, XG; Tian, XB; Tian, YK; Wang, P; Wang, XY; Xu, Y; Yang, H | 1 |
3 review(s) available for enkephalin, leucine and Chronic Pain
| Article | Year |
|---|---|
Dual Enkephalinase Inhibitors and Their Role in Chronic Pain Management.
Topics: CD13 Antigens; Chronic Pain; Dipeptides; Disulfides; Enkephalins; Enzyme Inhibitors; Humans; Neprilysin; Phenylalanine; Propionates; Propylamines | 2021 |
Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain.
Topics: Amidohydrolases; Analgesics; Animals; Cannabinoid Receptor Modulators; Chronic Pain; Enkephalins; Humans | 2012 |
Targeted drug delivery to the peripheral nervous system using gene therapy.
Topics: Animals; Chronic Pain; Clinical Trials as Topic; Diabetic Neuropathies; Enkephalins; Genetic Therapy; Genetic Vectors; Herpesviridae; Humans; Neoplasms; Nerve Growth Factors; Neurotransmitter Agents; Pain, Intractable; Peripheral Nervous System; Polyneuropathies; Protein Precursors | 2012 |
6 other study(ies) available for enkephalin, leucine and Chronic Pain
| Article | Year |
|---|---|
Contribution of the μ opioid receptor and enkephalin to the antinociceptive actions of endomorphin-1 analogs with unnatural amino acid modifications in the spinal cord.
Topics: Analgesics; Animals; Chronic Pain; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Mice; Naloxone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu; Spinal Cord | 2021 |
Activation of enkephalinergic (Enk) interneurons in the central amygdala (CeA) buffers the behavioral effects of persistent pain.
Topics: Animals; Anxiety; Central Amygdaloid Nucleus; Chronic Pain; Enkephalins; Interneurons; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia | 2019 |
Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain.
Topics: Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enkephalins; Fentanyl; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 2013 |
Efficacy of Herpes Simplex Virus Vector Encoding the Human Preproenkephalin Gene for Treatment of Facial Pain in Mice.
Topics: Administration, Topical; Animals; Chronic Pain; Disease Models, Animal; Enkephalins; Facial Pain; Genetic Therapy; Genetic Vectors; Humans; Injections, Subcutaneous; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein Precursors; Simplexvirus; Touch; Transduction, Genetic; Transfection; Transgenes; Trigeminal Ganglion; Trigeminal Neuralgia | 2016 |
Involvement of the dynorphin/KOR system on the nociceptive, emotional and cognitive manifestations of joint pain in mice.
Topics: Acetylation; Amygdala; Animals; Arthralgia; Chronic Pain; Cognition; Corticotropin-Releasing Hormone; Disease Models, Animal; Emotions; Enkephalins; Epigenesis, Genetic; Hippocampus; Histones; Hyperalgesia; Mice, Inbred C57BL; Mice, Knockout; Microglia; Osteoarthritis; Protein Precursors; Receptors, Opioid, kappa; Spinal Cord | 2017 |
[Analgesic effect of intrathecal transplant of immortalized rat astrocyte strain genetically modified by human preproenkephalin gene on rat chronic neuropathic pain].
Topics: Animals; Astrocytes; Cells, Cultured; Chronic Pain; Disease Models, Animal; Enkephalins; Genetic Therapy; Humans; Male; Neuralgia; Protein Precursors; Rats; Rats, Sprague-Dawley | 2005 |