enkephalin, leucine and Akinetic-Rigid Variant of Huntington Disease

enkephalin, leucine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199012 (23.08)18.7374
1990's11 (21.15)18.2507
2000's18 (34.62)29.6817
2010's6 (11.54)24.3611
2020's5 (9.62)2.80

Authors

AuthorsStudies
Abu-Rumeileh, S; Al Shweiki, MHDR; Barba, L; Barschke, P; Gaetani, L; Halbgebauer, S; Landwehrmeyer, GB; Lewerenz, J; Ludolph, AC; Oeckl, P; Otto, M; Paolini Paoletti, F; Parnetti, L; Steinacker, P1
Chen, H; Chen, L; Chen, XY; Xue, Y1
Al Shweiki, MR; Anderl-Straub, S; Barschke, P; Bernhard Landwehrmeyer, G; Halbgebauer, S; Lewerenz, J; Ludolph, AC; Oeckl, P; Otto, M; Pachollek, A; Steinacker, P1
Abujrais, S; Bergquist, J; Burman, J; Constantinescu, R; Kneider, M; Landtblom, AM; Niemela, V; Nyholm, D; Paucar, M; Shevchenko, G; Sundblom, J; Svenningsson, P1
Bang, J; Ross, CA1
Bissonnette, S; Drolet, G; Hébert, SS; Samadi, P; Vaillancourt, M1
Gasparini, F; Gomez-Mancilla, B; Gulya, K; Gulyás, B; Halldin, C; Jia, Z; Maguire, RP; Schumacher, M; Sovago, J; Szigeti, C1
Angus, S; Bennett, CF; Cheng, SH; Hayden, MR; Hung, GH; Sardi, PS; Shihabuddin, LS; Stanek, LM; Yang, W1
Aebischer, P; Déglon, N; Gokce, O; Kuhn, A; Luthi-Carter, R; Perrin, V; Régulier, E; Runne, H; Sick, B; Zala, D1
Allen, KL; Faull, RL; Glass, M; Waldvogel, HJ1
Blum, D; Ledent, C; Mievis, S1
Bissada, N; Davis, NG; Doty, C; Drisdel, RC; Franciosi, S; Green, WN; Hayden, MR; Henkelman, RM; Hines, R; Huang, K; Lerch, JP; Milnerwood, AJ; Raymond, LA; Sanders, SS; Singaraja, RR; Vaid, K; Wan, J; Young, FB1
Bhattacharyya, NP; Datta, M1
Chesselet, MF; Li, H; Li, XJ; Menalled, LB; Olivieri, M; Sison, JD; Wu, Y; Zeitlin, S1
Bantubungi, K; Blum, D; d'Alcantara, P; Galas, MC; Gall, D; Schiffmann, SN1
Del Mar, N; Goldowitz, D; Meade, C; Reiner, A; Sun, Z1
Reiner, A1
Alberch, J; Bosch, M; Canals, JM; Ernfors, P; Martín-Ibañez, R; Mengod, G; Muñoz, MT; Pineda, JR; Torres-Peraza, JF1
Augood, SJ; Cantuti-Castelvetri, I; Cha, JH; Farrell, LA; Keller-McGandy, CE; Menon, AS; Sadri-Vakili, G; Standaert, DG; Yohrling, GJ1
Ryan, AB; Scrable, H; Zeitlin, SO1
Benn, CL; Cha, JH; Deng, Y; Farrell, LA; Graham, R; Hayden, MR; Slow, EJ1
Benraiss, A; Chmielnicki, E; Cho, SR; Economides, A; Goldman, SA; Samdani, A1
An, JJ; Gharami, K; Tonegawa, S; Xie, Y; Xu, B1
Arregui, A; Clement-Jones, V; Emson, PC; Rossor, M; Sandberg, BE1
Bouras, C; Constantinidis, J; Richard, J1
Aizawa, H; Bird, E; DiFiglia, M; Ge, P; Penney, J; Sapp, E; Vonsattel, JP; Young, AB1
Cox, C; Gilmore, J; Maguire-Zeiss, KA; Richfield, EK; Voorn, P1
Maguire-Zeiss, KA; Richfield, EK; Vonkeman, HE; Voorn, P1
Augood, SJ; Emson, PC; Faull, RL; Love, DR1
Chen, Q; Reiner, A1
Cicchetti, F; Hayden, MR; Nasir, J; O'Kusky, JR; Parent, A1
Bordelon, YM; Chesselet, MF1
Carpenter, E; Chesselet, MF; Koppel, A; MacKenzie, L; Menalled, L; Zanjani, H; Zeitlin, S1
Figueredo-Cardenas, G; Fusco, F; Meade, CA; Nowak, TS; Pulsinelli, WA; Reiner, A1
Akerund, P; Alberch, J; Arenas, E; Canudas, AM; Pérez-Navarro, E1
Barami, K; Hutchins, KD; Lyman, WD1
Alberch, J; Arenas, E; Marco, S; Pérez-Navarro, E; Tolosa, E1
Deng, YP; MacDonald, ME; Reiner, A; Richfield, EK; Sun, Z; Vonsattel, JP1
Calne, DB; Chase, TN; Eisler, T; Nutt, JG; Rosin, AJ1
Kanazawa, I1
Albin, RL; Anderson, KD; Balfour, R; Dure, LS; Handelin, B; Penney, JB; Reiner, A; Whetsell, WO; Young, AB1
Albin, RL; Chesselet, MF; Penney, JB; Qin, Y; Young, AB1
Tan, MX1
Hunt, SP; Peck, R; Reynolds, GP; Rossor, M; Waters, CM1
Albin, RL; Anderson, KD; D'Amato, CJ; Penney, JB; Reiner, A; Young, AB1
Iadarola, MJ; Mouradian, MM1
Brownstein, MJ; Dawbarn, D; Emson, PC; Hunt, SP; Waters, CM; Zamir, N1
Gerstenbrand, F; Poewe, W1
Landis, DM; Marshall, PE; Zalneraitis, EL1
Albano, C; Loeb, C; Serrati, C1
Anderson, KD; Chen, Q; Figueredo-Cardenas, G; Reiner, A; Veenman, CL1
Beal, MF; Burd, GD; Landis, DM; Marshall, PE; Martin, JB1

Reviews

3 review(s) available for enkephalin, leucine and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
The globus pallidus as a target for neuropeptides and endocannabinoids participating in central activities.
    Peptides, 2020, Volume: 124

    Topics: Animals; Endocannabinoids; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Neuropeptides; Parkinson Disease; Substance P

2020
Putative peptide neurotransmitters in human neuropathology: a review of topography and clinical implications.
    Clinical neuropathology, 1983, Volume: 2, Issue:2

    Topics: Alzheimer Disease; Brain Mapping; Central Nervous System Diseases; Cholecystokinin; Enkephalins; Humans; Huntington Disease; Limbic System; Nerve Tissue Proteins; Neurotransmitter Agents; Parkinson Disease; Schizophrenia; Substance P; Substance-Related Disorders

1983
[Peptide neurotransmitters and extrapyramidal disorders].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1985, Volume: 18, Issue:4

    Topics: Animals; Basal Ganglia Diseases; Enkephalins; Humans; Huntington Disease; MSH Release-Inhibiting Hormone; Parkinson Disease; Substance P

1985

Trials

1 trial(s) available for enkephalin, leucine and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Effect of an opiate antagonist on movement disorders.
    Archives of neurology, 1978, Volume: 35, Issue:12

    Topics: Adult; Aged; Clinical Trials as Topic; Enkephalins; Humans; Huntington Disease; Middle Aged; Naloxone; Naltrexone; Parkinson Disease

1978

Other Studies

48 other study(ies) available for enkephalin, leucine and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Cerebrospinal fluid levels of proenkephalin and prodynorphin are differentially altered in Huntington's and Parkinson's disease.
    Journal of neurology, 2022, Volume: 269, Issue:9

    Topics: Biomarkers; Chromatography, Liquid; Dopamine; Enkephalins; Humans; Huntington Disease; Parkinson Disease; Protein Precursors; Tandem Mass Spectrometry

2022
Cerebrospinal Fluid Levels of Prodynorphin-Derived Peptides are Decreased in Huntington's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2021, Volume: 36, Issue:2

    Topics: Corpus Striatum; Enkephalins; Humans; Huntingtin Protein; Huntington Disease; Neurofilament Proteins; Peptides; Protein Precursors

2021
Proenkephalin Decreases in Cerebrospinal Fluid with Symptom Progression of Huntington's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2021, Volume: 36, Issue:2

    Topics: Biomarkers; Disease Progression; Enkephalins; Humans; Huntington Disease; Neurons; Protein Precursors; Proteomics

2021
Cerebrospinal Fluid Markers of Medium Spiny Neuron Injury in Huntington's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2021, Volume: 36, Issue:2

    Topics: Corpus Striatum; Enkephalins; Humans; Huntington Disease; Neurons; Peptides; Protein Precursors

2021
Striatal pre-enkephalin overexpression improves Huntington's disease symptoms in the R6/2 mouse model of Huntington's disease.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Enkephalins; Female; Gene Expression Regulation; Genetic Vectors; Globus Pallidus; Green Fluorescent Proteins; Huntingtin Protein; Huntington Disease; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Receptors, Opioid; RNA, Messenger; Substantia Nigra

2013
Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P immunoreactivity in Huntington's disease: a preliminary investigation in the postmortem human brain.
    Brain structure & function, 2015, Volume: 220, Issue:5

    Topics: Aged; Autopsy; Brain; Enkephalins; Female; Humans; Huntington Disease; Male; Middle Aged; Positron-Emission Tomography; Receptor, Metabotropic Glutamate 5; Substance P

2015
Antisense oligonucleotide-mediated correction of transcriptional dysregulation is correlated with behavioral benefits in the YAC128 mouse model of Huntington's disease.
    Journal of Huntington's disease, 2013, Volume: 2, Issue:2

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Gene Expression Regulation; Huntingtin Protein; Huntington Disease; Hypoxanthine Phosphoribosyltransferase; Infusions, Intraventricular; Mice; Motor Skills; Neostriatum; Nerve Tissue Proteins; Nuclear Proteins; Oligonucleotides, Antisense; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Receptors, Dopamine D1; Receptors, Dopamine D2

2013
Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-24, Volume: 28, Issue:39

    Topics: Animals; Corpus Striatum; Disease Models, Animal; Embryo, Mammalian; Enkephalins; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Huntington Disease; Lentivirus; Microarray Analysis; Mutation; Neurons; Peptides; Phosphoproteins; Protein Precursors; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; RGS Proteins; Transfection

2008
Cannabinoid (CB(1)), GABA(A) and GABA(B) receptor subunit changes in the globus pallidus in Huntington's disease.
    Journal of chemical neuroanatomy, 2009, Volume: 37, Issue:4

    Topics: Aged; Aged, 80 and over; Brain Mapping; Cannabinoid Receptor Modulators; Down-Regulation; Enkephalins; Female; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Huntington Disease; Immunohistochemistry; Male; Microscopy, Confocal; Middle Aged; Nerve Degeneration; Neuronal Plasticity; Neurons; Receptor, Cannabinoid, CB1; Receptors, GABA-A; Receptors, GABA-B; Substance P; Up-Regulation

2009
A2A receptor knockout worsens survival and motor behaviour in a transgenic mouse model of Huntington's disease.
    Neurobiology of disease, 2011, Volume: 41, Issue:2

    Topics: Animals; Enkephalins; Female; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Movement Disorders; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Receptor, Adenosine A2A; Survival Rate

2011
Altered palmitoylation and neuropathological deficits in mice lacking HIP14.
    Human molecular genetics, 2011, Oct-15, Volume: 20, Issue:20

    Topics: Acyltransferases; Animals; Cell Death; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Huntington Disease; Lipoylation; Mice; Mice, Knockout; Motor Activity; Mutant Proteins; Nerve Tissue Proteins; Neurons; Serotonin Plasma Membrane Transport Proteins; Synapses

2011
Regulation of RE1 protein silencing transcription factor (REST) expression by HIP1 protein interactor (HIPPI).
    The Journal of biological chemistry, 2011, Sep-30, Volume: 286, Issue:39

    Topics: Adaptor Proteins, Signal Transducing; Animals; Brain-Derived Neurotrophic Factor; Down-Regulation; Enkephalins; HEK293 Cells; HeLa Cells; Humans; Huntington Disease; Mice; Models, Biological; Protein Precursors; Repressor Proteins; Response Elements; Transcription, Genetic

2011
Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Sep-15, Volume: 22, Issue:18

    Topics: Animals; Behavior, Animal; Cell Count; Cell Nucleus; Corpus Striatum; Disease Models, Animal; Disease Progression; Enkephalins; Female; Grooming; Huntingtin Protein; Huntington Disease; Inclusion Bodies; Macromolecular Substances; Male; Mice; Mice, Mutant Strains; Motor Activity; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Organ Specificity; Phenotype; Receptors, Opioid, mu; RNA, Messenger; Trinucleotide Repeat Expansion

2002
The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Oct-15, Volume: 22, Issue:20

    Topics: Adenosine; Animals; Behavior, Animal; Binding, Competitive; Body Weight; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dystonia; Enkephalins; Hindlimb; Huntington Disease; In Vitro Techniques; Male; Mitochondria; Motor Activity; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred Lew; Reproducibility of Results; RNA, Messenger; Succinate Dehydrogenase; Synaptic Transmission; Treatment Outcome

2002
Differential changes in striatal projection neurons in R6/2 transgenic mice for Huntington's disease.
    Neurobiology of disease, 2002, Volume: 11, Issue:3

    Topics: Age Factors; Animals; Autoradiography; Corpus Striatum; Disease Models, Animal; Enkephalins; Gene Expression; Genotype; Globus Pallidus; Huntington Disease; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Transgenic; Neural Pathways; Neurons; Nucleus Accumbens; Protein Precursors; RNA, Messenger; Substance P; Substantia Nigra; Tachykinins

2002
Can lesions of GPe correct HD deficits?
    Experimental neurology, 2004, Volume: 186, Issue:1

    Topics: Animals; Disease Models, Animal; Enkephalins; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Huntington Disease; Substance P

2004
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-01, Volume: 24, Issue:35

    Topics: Age of Onset; Animals; Ataxia; Brain-Derived Neurotrophic Factor; Cell Death; Cell Line, Transformed; Chorea; Corpus Striatum; Crosses, Genetic; Endocytosis; Enkephalins; Gene Expression Regulation; Huntingtin Protein; Huntington Disease; Mice; Mice, Knockout; Mice, Transgenic; Movement Disorders; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phenotype; Stem Cells; Transfection; Trinucleotide Repeats

2004
Huntingtin inclusions do not down-regulate specific genes in the R6/2 Huntington's disease mouse.
    The European journal of neuroscience, 2006, Volume: 23, Issue:12

    Topics: Animals; Disease Models, Animal; Down-Regulation; Enkephalins; Gene Expression Regulation; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; In Situ Hybridization; Intranuclear Inclusion Bodies; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Protein Precursors; Receptors, Dopamine D2; Somatostatin

2006
Genetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesis.
    Neurobiology of disease, 2006, Volume: 24, Issue:2

    Topics: Alleles; Animals; Brain; Disease Models, Animal; Enkephalins; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Huntingtin Protein; Huntington Disease; Intranuclear Inclusion Bodies; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Protein Precursors; RNA, Messenger; Tumor Suppressor Protein p53; Up-Regulation

2006
Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington's disease.
    Neuroscience, 2007, Jun-29, Volume: 147, Issue:2

    Topics: Animals; Autoradiography; Blotting, Western; Chromosomes, Artificial, Yeast; Enkephalins; Humans; Huntington Disease; In Situ Hybridization; Mice; Mice, Transgenic; Protein Precursors; Receptors, AMPA; Receptors, Dopamine; Receptors, GABA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; RNA, Messenger; Subcellular Fractions

2007
Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:10

    Topics: Adenoviridae; Animals; Brain-Derived Neurotrophic Factor; Carrier Proteins; Disease Models, Animal; Disease Progression; Enkephalins; Globus Pallidus; Huntington Disease; Mice; Mice, Transgenic; Mitosis; Neostriatum; Neurons; Regeneration; Substance P; Tubulin

2007
Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice.
    Journal of neurochemistry, 2008, Volume: 105, Issue:2

    Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Enkephalins; Gene Expression Regulation; Huntingtin Protein; Huntington Disease; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Prosencephalon

2008
Regional distribution of methionine-enkephalin and substance P-like immunoreactivity in normal human brain and in Huntington's disease.
    Brain research, 1980, Oct-13, Volume: 199, Issue:1

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Endorphins; Enkephalins; Humans; Huntington Disease; Mice; Middle Aged; Radioimmunoassay; Substance P

1980
Evidence for a preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis.
    Neuroscience, 1995, Volume: 64, Issue:2

    Topics: Aged; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Image Processing, Computer-Assisted; Immunochemistry; Microscopy; Middle Aged; Substance P

1995
Reduced expression of preproenkephalin in striatal neurons from Huntington's disease patients.
    Annals of neurology, 1995, Volume: 37, Issue:3

    Topics: Adult; Aged; Blotting, Northern; Enkephalins; Female; Gene Expression Regulation; Humans; Huntington Disease; In Situ Hybridization; Male; Middle Aged; Neostriatum; Oligonucleotide Probes; Protein Precursors; RNA, Messenger; Sensitivity and Specificity

1995
Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients.
    Annals of neurology, 1995, Volume: 38, Issue:6

    Topics: Adult; Aged; Blotting, Northern; Calbindin 1; Calbindins; Enkephalins; Female; Histocytochemistry; Humans; Huntington Disease; In Situ Hybridization; Male; Middle Aged; Neostriatum; Nerve Tissue Proteins; Neurons; Oligonucleotide Probes; Protein Precursors; RNA, Messenger; S100 Calcium Binding Protein G; Sensitivity and Specificity; Tachykinins

1995
Reduction in enkephalin and substance P messenger RNA in the striatum of early grade Huntington's disease: a detailed cellular in situ hybridization study.
    Neuroscience, 1996, Volume: 72, Issue:4

    Topics: Aged; Aged, 80 and over; Enkephalins; Female; Gene Expression; Humans; Huntington Disease; Image Processing, Computer-Assisted; In Situ Hybridization; Male; Middle Aged; Neostriatum; RNA, Messenger; Substance P

1996
Cellular distribution of the NMDA receptor NR2A/2B subunits in the rat striatum.
    Brain research, 1996, Dec-16, Volume: 743, Issue:1-2

    Topics: Acetylcholine; Animals; Calbindins; Corpus Striatum; Enkephalins; Huntington Disease; Interneurons; Male; Nerve Tissue Proteins; Neurons; Parvalbumins; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S100 Calcium Binding Protein G; Somatostatin; Substance P

1996
Neuronal degeneration in the basal ganglia and loss of pallido-subthalamic synapses in mice with targeted disruption of the Huntington's disease gene.
    Brain research, 1999, Feb-13, Volume: 818, Issue:2

    Topics: Afferent Pathways; Animals; Basal Ganglia; Enkephalins; Gene Targeting; Globus Pallidus; Heterozygote; Huntington Disease; Immunohistochemistry; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroglia; Neurons; Substance P; Synapses; Thalamic Nuclei

1999
Early effects of intrastriatal injections of quinolinic acid on microtubule-associated protein-2 and neuropeptides in rat basal ganglia.
    Neuroscience, 1999, Volume: 93, Issue:3

    Topics: Animals; Basal Ganglia; Corpus Striatum; Cytoskeleton; Disease Models, Animal; DNA Damage; Efferent Pathways; Enkephalins; Excitatory Amino Acid Agonists; Globus Pallidus; Huntington Disease; Injections; Male; Mice; Mice, Neurologic Mutants; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P

1999
Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease.
    Experimental neurology, 2000, Volume: 162, Issue:2

    Topics: Animals; Biomarkers; Calbindins; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; DNA Damage; Enkephalins; Female; Glutamate Decarboxylase; Homozygote; Huntingtin Protein; Huntington Disease; Isoenzymes; Male; Mice; Mice, Knockout; Mice, Neurologic Mutants; Motor Activity; Nerve Tissue Proteins; Neurons; Nuclear Proteins; RNA, Messenger; S100 Calcium Binding Protein G; Substance P; Trinucleotide Repeats

2000
Transient global ischemia in rats yields striatal projection neuron and interneuron loss resembling that in Huntington's disease.
    Experimental neurology, 2000, Volume: 166, Issue:2

    Topics: Animals; Cell Survival; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Enkephalins; Huntington Disease; Image Processing, Computer-Assisted; Interneurons; Ischemic Attack, Transient; Male; NADPH Dehydrogenase; Nerve Fibers; Neural Pathways; Rats; Rats, Sprague-Dawley; Rats, Wistar; Somatostatin; Substance P

2000
Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease.
    Journal of neurochemistry, 2000, Volume: 75, Issue:5

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Death; Cell Line; Cell Transplantation; Corpus Striatum; Disease Models, Animal; Enkephalins; Fibroblasts; Glutamate Decarboxylase; Huntington Disease; Isoenzymes; Male; Nerve Growth Factors; Neurons; Neurotrophin 3; Phosphorylation; Protein Precursors; Quinolinic Acid; Rats; Rats, Inbred F344; Receptor, trkB; Tachykinins

2000
Neurotransmitter distribution in the second trimester fetal human corpus striatum.
    Neurological research, 2001, Volume: 23, Issue:1

    Topics: Acetylcholine; Age Factors; Brain Tissue Transplantation; Corpus Striatum; Enkephalins; Female; Fetal Tissue Transplantation; Fetus; gamma-Aminobutyric Acid; Humans; Huntington Disease; Neurons; Neuropeptide Y; Neurotransmitter Agents; Pregnancy; Pregnancy Trimester, Second; Substance P

2001
Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease.
    Journal of neurobiology, 2002, Volume: 50, Issue:4

    Topics: Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Enkephalins; Globus Pallidus; Glutamate Decarboxylase; Huntington Disease; Isoenzymes; Male; Neostriatum; Nerve Growth Factors; Neural Pathways; Neurons; Neuroprotective Agents; Neurotoxins; Neurturin; Protein Precursors; Quinolinic Acid; Rats; Rats, Inbred F344; RNA, Messenger; Tachykinins

2002
Selective loss of striatal preprotachykinin neurons in a phenocopy of Huntington's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17, Issue:2

    Topics: Aged; Cell Survival; Corpus Striatum; Enkephalins; Female; Gene Expression; Globus Pallidus; Humans; Huntington Disease; Neurologic Examination; Neurons; Phenotype; Polymerase Chain Reaction; Protein Precursors; Substance P; Tachykinins; Trinucleotide Repeats

2002
On chorea: possible neuronal mechanisms.
    Clinical neurology and neurosurgery, 1992, Volume: 94 Suppl

    Topics: Animals; Brain Mapping; Corpus Striatum; Dopamine; Enkephalins; gamma-Aminobutyric Acid; Humans; Huntington Disease; Macaca; Nerve Degeneration; Neural Pathways; Substantia Nigra

1992
Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease.
    Annals of neurology, 1992, Volume: 31, Issue:4

    Topics: Adult; Cell Survival; Corpus Striatum; Enkephalins; Glial Fibrillary Acidic Protein; Globus Pallidus; Humans; Huntington Disease; Immunohistochemistry; Male; Neurons; Substance P; Synaptic Transmission

1992
Preproenkephalin messenger RNA-containing neurons in striatum of patients with symptomatic and presymptomatic Huntington's disease: an in situ hybridization study.
    Annals of neurology, 1991, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoradiography; Child; Corpus Striatum; Enkephalins; Humans; Huntington Disease; Middle Aged; Neurons; Nucleic Acid Hybridization; Protein Precursors; RNA Probes; RNA, Messenger

1991
Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's chorea.
    Neuroscience, 1988, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Basal Ganglia; Catecholamines; Cell Count; Enkephalins; Female; Humans; Huntington Disease; Immunohistochemistry; Male; Middle Aged; Parkinson Disease; Substance P; Substantia Nigra

1988
Differential loss of striatal projection neurons in Huntington disease.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:15

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Axons; Child; Corpus Striatum; Enkephalins; Humans; Huntington Disease; Immunohistochemistry; Middle Aged; Neurons; Substance P

1988
Decrease in a proenkephalin peptide in cerebrospinal fluid in Huntington's disease and progressive supranuclear palsy.
    Brain research, 1989, Feb-13, Volume: 479, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Enkephalin, Methionine; Enkephalins; Humans; Huntington Disease; Middle Aged; Protein Precursors; Supranuclear Palsy, Progressive

1989
Peptides derived from prodynorphin are decreased in basal ganglia of Huntington's disease brains.
    Brain research, 1986, Apr-30, Volume: 372, Issue:1

    Topics: Basal Ganglia; Caudate Nucleus; Dynorphins; Endorphins; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Protein Precursors; Putamen; Substantia Nigra

1986
Dopaminergic-peptidergic interactions in extrapyramidal disorders: a review of the clinical evidence.
    Advances in neurology, 1987, Volume: 45

    Topics: Basal Ganglia; Brain; Dopamine; Enkephalins; Humans; Huntington Disease; MSH Release-Inhibiting Hormone; Neuropeptides; Parkinson Disease

1987
Immunocytochemical studies of substance P and leucine-enkephalin in Huntington's disease.
    Brain research, 1983, Dec-19, Volume: 289, Issue:1-2

    Topics: Adolescent; Adult; Aged; Brain; Caudate Nucleus; Corpus Striatum; Enkephalin, Leucine; Globus Pallidus; Humans; Huntington Disease; Immunoenzyme Techniques; Middle Aged; Nerve Degeneration; Neural Pathways; Neurons; Putamen; Substance P; Substantia Nigra

1983
[Cerebrospinal fluid levels of leucine enkephalin and methionine enkephalin in patients with altered behavior].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1984, Volume: 134, Issue:1

    Topics: Adult; Aged; Alzheimer Disease; Depressive Disorder; Enkephalin, Leucine; Enkephalin, Methionine; Female; Humans; Huntington Disease; Male; Middle Aged; Neurocognitive Disorders; Schizophrenia, Paranoid

1984
Relative survival of striatal projection neurons and interneurons after intrastriatal injection of quinolinic acid in rats.
    Experimental neurology, 1994, Volume: 129, Issue:1

    Topics: Animals; Antibodies; Cell Survival; Choline O-Acetyltransferase; Corpus Striatum; Efferent Pathways; Enkephalin, Leucine; Enkephalin, Methionine; Globus Pallidus; Huntington Disease; Immunohistochemistry; Interneurons; Male; Microinjections; Nerve Fibers; Neurons; Neuropeptide Y; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Somatostatin

1994
Excitotoxin lesions do not mimic the alteration of somatostatin in Huntington's disease.
    Brain research, 1985, Dec-30, Volume: 361, Issue:1-2

    Topics: Animals; Brain; Corpus Striatum; Disease Models, Animal; Enkephalin, Leucine; Humans; Huntington Disease; Ibotenic Acid; Immune Sera; Immunoassay; Kainic Acid; Male; Neurons; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Tissue Distribution

1985