enkephalin, leucine has been researched along with Adjuvant Arthritis in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (28.57) | 18.7374 |
| 1990's | 12 (42.86) | 18.2507 |
| 2000's | 5 (17.86) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Madol, M; Khalefa, BI; Li, L; Mousa, SA; Schäfer, M; Shaqura, M; Treskatsch, S | 1 |
| Broere, F; de Wolf, C; den Braber, I; Favry, E; Glant, T; Hoek, A; Koning, F; Ludwig, I; Maillère, B; van der Zee, R; van Eden, W; van Lummel, M | 1 |
| Baddack-Werncke, U; Busch-Dienstfertig, M; González-Rodríguez, S; Grobe, J; Lipp, M; Maddila, SC; Müller, G; Stein, C | 1 |
| Lu, Y; McNearney, TA; Westlund, KN; Wilson, SP; Yeomans, DC | 1 |
| Bourgoin, S; Cesselin, F; Gros, C; Hamon, M; Montastruc, JL | 1 |
| Kar, S; Quirion, R; Rees, RG | 1 |
| Fournié-Zaluski, MC; Guilbaud, G; Kayser, V; Perrot, S; Roques, BP | 1 |
| Bourgoin, S; Cesselin, F; Collin, E; Frechilla, D; Hamon, M; Mantelet, S; Pohl, M | 1 |
| Desmeules, JA; Gacel, G; Guilbaud, G; Kayser, V; Roques, BP | 1 |
| Hall, TJ; Jagher, B; Schaeublin, M; Wiesenberg, I | 1 |
| Ballet, S; Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A; Pohl, M | 1 |
| Hukuda, S; Imai, S; Maeda, T; Omura, K | 1 |
| Benavides, J; Fournié-Zaluski, MC; Nieto, MM; Noble, F; Roques, BP; Walker, J; Wilson, J | 1 |
| Beaufour, C; Braz, J; Cesselin, F; Coutaux, A; Epstein, AL; Hamon, M; Pohl, M | 1 |
| Besse, D; Besson, JM; Butler, SH; Lombard, MC; Weil-Fugazza, J | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 1 |
| Brewerton, DA; Gibson, SJ; Jura, WG; Kar, S; Polak, JM; Rees, RG | 1 |
| Haarmann, I; Herz, A; Höllt, V; Millan, MJ | 1 |
| Gramsch, C; Herz, A; Millan, MJ; Müller, S; Nohr, D; Stein, C; Weihe, E | 1 |
| Bernardini, R; Calogero, AE; Chrousos, GP; Gold, PW; Sternberg, EM; Wilder, RL; Young, WS | 1 |
| Fournie-Zaluski, MC; Guilbaud, G; Kayser, V; Roques, BP | 1 |
| Cox, ML; Welch, SP | 1 |
| Hultenby, K; Lindgren, UJ; Wu, Q | 1 |
| Butler, SH; Nyberg, F; Persson, S; Post, C; Weil-Fugazza, J | 1 |
| Bhattacharya, SK; Saraswati, M; Sen, AP | 1 |
| Cao, WH; Deng, Y; Dong, XT; Lu, ZS; Zhang, TJ | 1 |
| Colpaert, FC; Członkowski, A; Herz, A; Höllt, V; Millan, MH; Millan, MJ; Pilcher, CW | 1 |
| Hu, WD; Liu, HW; Mu, JA; Qiu, NY; Zhang, JX | 1 |
1 review(s) available for enkephalin, leucine and Adjuvant Arthritis
| Article | Year |
|---|---|
Functional response of multiple opioid systems to chronic arthritic pain in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Arthritis; Arthritis, Experimental; Benzomorphans; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Morphine; Naloxone; Nociceptors; Pain; Pituitary Gland, Anterior; Protein Precursors; Pyrrolidines; Rats; Receptors, Opioid; Sensory Thresholds; Spinal Cord; Thalamus | 1986 |
27 other study(ies) available for enkephalin, leucine and Adjuvant Arthritis
| Article | Year |
|---|---|
Functional and Anatomical Characterization of Corticotropin-Releasing Factor Receptor Subtypes of the Rat Spinal Cord Involved in Somatic Pain Relief.
Topics: Acenaphthenes; Amphibian Proteins; Animals; Arthritis, Experimental; Corticotropin-Releasing Hormone; Enkephalins; Hyperalgesia; Interneurons; Male; Naloxone; Nociception; Pain; Peptide Hormones; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Spinal Cord; Urocortins | 2021 |
An Arthritis-Suppressive and Treg Cell-Inducing CD4+ T Cell Epitope Is Functional in the Context of HLA-Restricted T Cell Responses.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Binding, Competitive; CD4-Positive T-Lymphocytes; Cell Separation; Cells, Cultured; Cross Reactions; Enkephalins; Epitopes, T-Lymphocyte; Female; Forkhead Transcription Factors; HLA-DQ Antigens; Humans; In Vitro Techniques; Integrin beta1; Interleukin-2 Receptor alpha Subunit; Major Histocompatibility Complex; Mice; Mice, Inbred BALB C; Mice, Transgenic; Protein Precursors; T-Lymphocytes; T-Lymphocytes, Regulatory | 2016 |
Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis.
Topics: Analgesics, Opioid; Animals; Antibodies; Arthritis, Experimental; CD8 Antigens; CD8-Positive T-Lymphocytes; Collagen; Disease Models, Animal; Enkephalins; Female; Freund's Adjuvant; Functional Laterality; Hyperalgesia; Inflammation; Methionine; Mice; Mice, Inbred BALB C; Pain Measurement; Pain Threshold; Time Factors | 2017 |
Joint capsule treatment with enkephalin-encoding HSV-1 recombinant vector reduces inflammatory damage and behavioural sequelae in rat CFA monoarthritis.
Topics: Animals; Arthritis, Experimental; Behavior, Animal; Enkephalins; Freund's Adjuvant; Gene Targeting; Genetic Vectors; Herpesvirus 1, Human; Inflammation; Inflammation Mediators; Joint Capsule; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2008 |
Met-enkephalin levels and opiate receptors in the spinal cord of chronic suffering rats.
Topics: Animals; Arthritis, Experimental; Endorphins; Enkephalins; Naloxone; Pain, Intractable; Rats; Receptors, Opioid; Spinal Cord | 1980 |
Altered calcitonin gene-related peptide, substance P and enkephalin immunoreactivities and receptor binding sites in the dorsal spinal cord of the polyarthritic rat.
Topics: Animals; Arthritis, Experimental; Autoradiography; Calcitonin Gene-Related Peptide; Enkephalins; Immunohistochemistry; In Vitro Techniques; Male; Neuropeptides; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Receptors, Opioid; Spinal Cord; Substance P | 1994 |
Antinociceptive effect of systemic PC 12, a prodrug mixed inhibitor of enkephalin-degrading enzymes, in normal and arthritic rats.
Topics: Aminopeptidases; Analgesics; Animals; Arthritis, Experimental; CD13 Antigens; Dose-Response Relationship, Drug; Enkephalins; Glycine; Male; Naloxone; Neprilysin; Pain; Pain Measurement; Prodrugs; Rats; Rats, Sprague-Dawley; Vocalization, Animal | 1993 |
Increased in vivo release of calcitonin gene-related peptide-like material from the spinal cord in arthritic rats.
Topics: Analgesics; Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ganglia, Spinal; Injections, Spinal; Iodine Radioisotopes; Male; Naloxone; Perfusion; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord | 1993 |
The highly selective delta agonist BUBU induces an analgesic effect in normal and arthritic rat and this action is not affected by repeated administration of low doses of morphine.
Topics: Analgesics; Animals; Arthritis, Experimental; Drug Administration Schedule; Drug Interactions; Enkephalins; Male; Morphine; Naloxone; Naltrexone; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reference Values; Vocalization, Animal | 1993 |
The analgesic drug buprenorphine inhibits osteoclastic bone resorption in vitro, but is proinflammatory in rat adjuvant arthritis.
Topics: Analgesics; Analgesics, Opioid; Animals; Arthritis, Experimental; Arthrography; Bone Resorption; Buprenorphine; Cells, Cultured; Disease Models, Animal; Edema; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Femur; Lethal Dose 50; Naloxone; Narcotic Antagonists; Osteoclasts; Rats | 1996 |
Enkephalinergic and dynorphinergic neurons in the spinal cord and dorsal root ganglia of the polyarthritic rat - in vivo release and cDNA hybridization studies.
Topics: Animals; Arthritis, Experimental; Blotting, Northern; DNA, Complementary; Dynorphins; Enkephalins; Ganglia, Spinal; In Situ Hybridization; Male; Neurons; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord | 1997 |
Prolonged and increasing expression of Fos related antigens in the hippocampus of adjuvant arthritic rats.
Topics: Animals; Arthritis, Experimental; Enkephalins; Hippocampus; Immunohistochemistry; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar | 1998 |
Facilitation of enkephalins catabolism inhibitor-induced antinociception by drugs classically used in pain management.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Disulfides; Enkephalins; Enzyme Inhibitors; Formaldehyde; Injections, Intravenous; Injections, Subcutaneous; Male; Mice; Morphine; Neprilysin; Pain; Pain Measurement; Phenylalanine; Pressure; Rats; Rats, Sprague-Dawley; Reaction Time | 2001 |
Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons.
Topics: Animals; Arthritis; Arthritis, Experimental; Disease Models, Animal; Disease Progression; Enkephalins; Freund's Adjuvant; Ganglia, Spinal; Genes, Reporter; Genetic Therapy; Genetic Vectors; Herpesvirus 1, Human; Hindlimb; Hyperalgesia; Male; Neurons, Afferent; Pain Measurement; Protein Precursors; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Terminal Repeat Sequences; Treatment Outcome | 2001 |
Monoarthritis induces complex changes in mu-, delta- and kappa-opioid binding sites in the superficial dorsal horn of the rat spinal cord.
Topics: Animals; Arthritis; Arthritis, Experimental; Autoradiography; Benzeneacetamides; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Freund's Adjuvant; Male; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1992 |
Time-dependent changes in the activity of opioid systems in the spinal cord of monoarthritic rats--a release and in situ hybridization study.
Topics: Animals; Arthritis, Experimental; Endorphins; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Male; Nucleic Acid Hybridization; Oligonucleotide Probes; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; RNA, Messenger; Spinal Cord; Sulfur Radioisotopes | 1992 |
Increased calcitonin gene-related peptide (CGRP), substance P, and enkephalin immunoreactivities in dorsal spinal cord and loss of CGRP-immunoreactive motoneurons in arthritic rats depend on intact peripheral nerve supply.
Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Enkephalins; Functional Laterality; Ganglia, Spinal; Immunoenzyme Techniques; Male; Motor Neurons; Rats; Rats, Inbred Strains; Reference Values; Sciatic Nerve; Spinal Cord; Substance P | 1991 |
Prodynorphin gene expression is enhanced in the spinal cord of chronic arthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Body Weight; Enkephalins; Gene Expression Regulation; Male; Nucleic Acid Hybridization; Organ Size; Pain; Protein Precursors; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Spinal Cord | 1987 |
Peptide neuroanatomy of adjuvant-induced arthritic inflammation in rat.
Topics: Animals; Arthritis; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Enkephalins; Ganglia, Spinal; Immunohistochemistry; Nerve Fibers; Neuropeptides; Protein Precursors; Rats; Rats, Inbred Strains; Skin; Spinal Cord; Substance P | 1988 |
A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Brain; Cell Wall; Corticotropin-Releasing Hormone; Disease Susceptibility; Enkephalins; Female; Hypothalamus; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reference Values; Species Specificity; Streptococcus; Transcription, Genetic | 1989 |
Potent antinociceptive effects of kelatorphan (a highly efficient inhibitor of multiple enkephalin-degrading enzymes) systemically administered in normal and arthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Dipeptides; Dose-Response Relationship, Drug; Enkephalins; Enzyme Inhibitors; Male; Naloxone; Pain; Rats; Rats, Inbred Strains | 1989 |
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat.
Topics: Animals; Arthritis, Experimental; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Dronabinol; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Freund's Adjuvant; Injections, Intradermal; Injections, Intraperitoneal; Male; Morphine; Mycobacterium; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid; Rimonabant | 2004 |
Tissue levels of leu-enkephalin in rats with adjuvant arthritis.
Topics: Adjuvants, Immunologic; Animals; Ankle Joint; Arthritis, Experimental; Bone and Bones; Enkephalin, Leucine; Female; Microscopy, Immunoelectron; Radioimmunoassay; Rats; Rats, Inbred Lew; Spinal Cord | 2005 |
Decreased cerebrospinal fluid neuropeptide-converting enzyme activity in monoarthritic rats.
Topics: Animals; Arthritis, Experimental; Cerebrospinal Fluid; Cysteine Endopeptidases; Enkephalin, Leucine; Male; Metalloendopeptidases; Pain; Peptide Fragments; Rats; Rats, Sprague-Dawley; Substance P | 1992 |
Effect of centrally administered enkephalins on carrageenin-induced paw oedema in rats.
Topics: Animals; Arthritis, Experimental; Brain; Carrageenan; Edema; Enkephalin, Leucine; Enkephalin, Methionine; Female; Hindlimb; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Injections, Intraventricular; Male; Metyrapone; Morphine; Naloxone; Pituitary-Adrenal System; Rats; Rats, Wistar | 1992 |
Relation between the therapeutic effect of moxibustion in treating arthralgia and SP and enkephalin in nervous tissues.
Topics: Animals; Arthritis; Arthritis, Experimental; Enkephalin, Leucine; Male; Moxibustion; Pain; Rats; Rats, Inbred Strains; Sciatic Nerve; Sensory Thresholds; Spinal Cord; Substance P | 1989 |
[Influence of acupuncture on the leu-enkephalia content of the brain and spinal cord of rats].
Topics: Acupuncture Therapy; Animals; Arthritis; Arthritis, Experimental; Brain Chemistry; Electric Stimulation Therapy; Enkephalin, Leucine; Female; Male; Pituitary Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord | 1987 |