enkephalin, d-penicillamine (2,5)- and Disease Models, Animal

Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship

Topics: Aniline Compounds; Animals; Butyrates; Colitis; Disease Models, Animal; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Inflammation; Ligands; Male; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Peroxidase; Receptors, G-Protein-Coupled; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfonamides; Thiophenes; Xanthenes

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Locomotion; Male; Morphine; Pain Measurement; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Recovery of Function; Severity of Illness Index; Spinal Cord Injuries

Topics: Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Recurrence; Reward; Self Administration; Substance Withdrawal Syndrome

Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cell Death; Cells, Cultured; Disease Models, Animal; Enkephalin, D-Penicillamine (2,5)-; Heart Ventricles; Humans; Myocardial Contraction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Rats; Receptors, Adrenergic, beta-2; Receptors, Calcitonin Gene-Related Peptide; Receptors, Opioid, delta; Signal Transduction

Topics: Analgesics, Opioid; Animals; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Enkephalin, D-Penicillamine (2,5)-; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Pain Measurement; Receptors, Opioid, delta; Time Factors

Topics: Analgesics, Opioid; Animals; Anxiety; CA1 Region, Hippocampal; Disease Models, Animal; Enkephalin, D-Penicillamine (2,5)-; Male; Maze Learning; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu

Topics: Analgesics, Opioid; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Hot Temperature; Hyperalgesia; Indoles; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Morphine; Nitric Oxide; Sciatic Neuropathy

Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Enkephalin, D-Penicillamine (2,5)-; Levodopa; Male; Neurons; Parkinsonian Disorders; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta

Topics: Analgesics, Opioid; Animals; Anxiety; Central Nervous System Depressants; Conditioning, Operant; Disease Models, Animal; Enkephalin, D-Penicillamine (2,5)-; Ethanol; Hydrocortisone; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Maze Learning; Microinjections; Motor Activity; Narcotic Antagonists; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Inbred Lew; Receptors, Opioid, delta; Rotarod Performance Test; Self Administration; Statistics as Topic; Tetrahydroisoquinolines; Ventral Tegmental Area

Topics: Analgesics, Opioid; Animals; Animals, Newborn; Apoptosis; Astrocytes; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Drug Interactions; Encephalomyelitis, Autoimmune, Experimental; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Female; Gene Expression Regulation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Narcotic Antagonists; Necrosis; Nitric Oxide; Peptides; Receptors, Opioid; RNA, Small Interfering; Time Factors

Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Decanoic Acids; Disease Models, Animal; Drug Antagonism; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Glyburide; Hydroxy Acids; Male; Mitochondria, Heart; Myocardial Infarction; Myocardium; Naloxone; Potassium Channels; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Opioid, delta; Sclerosis; Ventricular Fibrillation

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Capsaicin; Carrageenan; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Enkephalin, D-Penicillamine (2,5)-; Extravasation of Diagnostic and Therapeutic Materials; Fentanyl; Hindlimb; Histamine Antagonists; Inflammation; Male; Morphine; Narcotic Antagonists; Oxidopamine; p-Methoxy-N-methylphenethylamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cell Membrane; Chlorocebus aethiops; CHO Cells; Cloning, Molecular; COS Cells; Cricetinae; Disease Models, Animal; DNA, Complementary; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Gene Deletion; GTP-Binding Proteins; Guanine; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Immunohistochemistry; Immunoprecipitation; Ligands; Microscopy, Fluorescence; Oligopeptides; Pertussis Toxin; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Time Factors; Transfection

Topics: Adamantane; Animals; Antidepressive Agents; Autoradiography; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gene Expression Regulation; Immobility Response, Tonic; In Situ Hybridization; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; RNA, Messenger; Swimming; Tetrahydroisoquinolines

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cerebral Infarction; Cerebral Ventricles; Disease Models, Animal; Drug Administration Routes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Oligopeptides; Rats; Rats, Sprague-Dawley; Treatment Outcome; Urinary Bladder, Overactive; Urodynamics

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enkephalin, D-Penicillamine (2,5)-; Exploratory Behavior; Hippocampus; Ischemia; Male; Maze Learning; Memory Disorders; Neurons; Rats; Rats, Wistar; Recovery of Function; Time Factors

Topics: Analysis of Variance; Animals; Coronary Circulation; Disease Models, Animal; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Female; Heart; Heart Arrest, Induced; Hibernation; Hypothermia, Induced; Male; Marmota; Myocardial Ischemia; Myocardial Stunning; Myocardium; Oxygen Consumption; Peptides; Premedication; Proteins; Rabbits; Receptors, Opioid, delta; Ursidae; Ventricular Function; Ventricular Function, Left; Ventricular Pressure

Topics: Animals; beta-Endorphin; Brain; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Hydrochloric Acid; Male; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach Ulcer; Vagotomy

Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Cardiac Surgical Procedures; Coronary Circulation; Disease Models, Animal; Drug Evaluation, Preclinical; Enkephalin, D-Penicillamine (2,5)-; Heart Arrest, Induced; Hypothermia, Induced; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Naltrexone; Narcotic Antagonists; Organ Size; Oxygen Consumption; Rabbits; Receptors, Opioid, delta; Recovery of Function; Stroke Volume; Ventricular Pressure

Topics: Animals; Arthritis; Arthritis, Experimental; Autoradiography; Benzeneacetamides; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Freund's Adjuvant; Male; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord

Topics: Animals; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Morphine; Pain Measurement; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu