enflurane has been researched along with Myocardial Ischemia in 11 studies
Enflurane: An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate.
enflurane : An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results of this trial suggest that a propofol-based anesthetic, when compared to an enflurane-based anesthetic requiring additional dosing of fentanyl and midazolam for CPB, can lead to a significant reduction in time to extubation after CABG surgery, without adverse hemodynamic effects, increased risk of myocardial ischemia or infarction." | 6.68 | Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery. ( Buckland, MR; Bujor, MA; Davis, BB; Hunt, JO; Langley, M; McRae, R; Moloney, JT; Myles, PS; Weeks, AM, 1997) |
| " We investigated the effects of ANP on pacing-induced myocardial ischemia during enflurane anesthesia in patients with coronary artery disease (CAD)." | 5.09 | Atrial natriuretic peptide attenuates pacing-induced myocardial ischemia during general anesthesia in patients with coronary artery disease. ( Hedner, T; Houltz, E; Kirnö, K; Lundin, S; Ricksten, SE; Saito, Y; Valsson, F, 1999) |
| " Clonidine reduced enflurane requirements, intraoperative tachycardia, and myocardial ischemia (1/28 clonidine patients vs 5/24 placebo, P = 0." | 5.07 | Premedication with oral and transdermal clonidine provides safe and efficacious postoperative sympatholysis. ( Busse, JR; Drijvers, G; Ellis, JE; Foss, JF; Laff, SP; Mantha, S; McKinsey, JF; Pedlow, S; Shah, M; Sorrentino, MJ, 1994) |
| " The results of this trial suggest that a propofol-based anesthetic, when compared to an enflurane-based anesthetic requiring additional dosing of fentanyl and midazolam for CPB, can lead to a significant reduction in time to extubation after CABG surgery, without adverse hemodynamic effects, increased risk of myocardial ischemia or infarction." | 2.68 | Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery. ( Buckland, MR; Bujor, MA; Davis, BB; Hunt, JO; Langley, M; McRae, R; Moloney, JT; Myles, PS; Weeks, AM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (81.82) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Landoni, G | 1 |
| Fochi, O | 1 |
| Zangrillo, A | 1 |
| Drenger, B | 1 |
| Gilon, D | 1 |
| Chevion, M | 1 |
| Elami, A | 1 |
| Meroz, Y | 1 |
| Milgalter, E | 1 |
| Gozal, Y | 1 |
| Louvier, N | 1 |
| Lançon, JP | 1 |
| Oguchi, T | 1 |
| Kashimoto, S | 1 |
| Yamaguchi, T | 1 |
| Nakamura, T | 1 |
| Kumazawa, T | 1 |
| Ellis, JE | 1 |
| Drijvers, G | 1 |
| Pedlow, S | 1 |
| Laff, SP | 1 |
| Sorrentino, MJ | 1 |
| Foss, JF | 1 |
| Shah, M | 1 |
| Busse, JR | 1 |
| Mantha, S | 1 |
| McKinsey, JF | 1 |
| Nathan, HJ | 1 |
| Smallman, B | 1 |
| Diana, P | 1 |
| Tullock, WC | 1 |
| Gorcsan, J | 1 |
| Ferson, PF | 1 |
| Arvan, S | 1 |
| Turner, LA | 1 |
| Polic, S | 1 |
| Hoffmann, RG | 1 |
| Kampine, JP | 1 |
| Bosnjak, ZJ | 1 |
| Myles, PS | 1 |
| Buckland, MR | 1 |
| Weeks, AM | 1 |
| Bujor, MA | 1 |
| McRae, R | 1 |
| Langley, M | 1 |
| Moloney, JT | 1 |
| Hunt, JO | 1 |
| Davis, BB | 1 |
| Valsson, F | 1 |
| Lundin, S | 1 |
| Kirnö, K | 1 |
| Hedner, T | 1 |
| Houltz, E | 1 |
| Saito, Y | 1 |
| Ricksten, SE | 1 |
| Rieke, H | 1 |
| Kazmaier, S | 1 |
| Lange, H | 1 |
| Weyland, A | 1 |
| Sonntag, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sevoflurane and Cardiac Protection in High Risk Patients Undergoing Cardiac Surgery. A Randomized Controlled Study.[NCT00821262] | Phase 4 | 200 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for enflurane and Myocardial Ischemia
| Article | Year |
|---|---|
[Do halogenated anesthetics protect from ischemic and reperfusion myocardial injuries?].
Topics: Animals; Calcium Channels; Cats; Dogs; Enflurane; Free Radicals; Halothane; Heart; Isoflurane; Myoca | 1994 |
6 trials available for enflurane and Myocardial Ischemia
| Article | Year |
|---|---|
Myocardial metabolism altered by ischemic preconditioning and enflurane in off-pump coronary artery surgery.
Topics: Aged; Coronary Artery Bypass, Off-Pump; Enflurane; Female; Humans; Ischemic Preconditioning, Myocard | 2008 |
Premedication with oral and transdermal clonidine provides safe and efficacious postoperative sympatholysis.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Anesthesia; Clonidine; Coronary Disease; Doub | 1994 |
Myocardial ischemia: a comparison between isoflurane and enflurane in coronary artery bypass patients.
Topics: Aged; Anesthesia, Inhalation; Coronary Artery Bypass; Enflurane; Female; Humans; Isoflurane; Male; M | 1993 |
Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery.
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Coronary Artery Bypass; Enflura | 1997 |
Atrial natriuretic peptide attenuates pacing-induced myocardial ischemia during general anesthesia in patients with coronary artery disease.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Atrial Natriuretic Factor; Blood Pressure | 1999 |
[Does method of anesthesia modify postoperative ischemia incidence? A study of patients after aortocoronary bypass operations].
Topics: Adult; Aged; Anesthesia, General; Coronary Artery Bypass; Electrocardiography; Enflurane; Fentanyl; | 1999 |
4 other studies available for enflurane and Myocardial Ischemia
| Article | Year |
|---|---|
Cardioprotection by volatile anesthetics in noncardiac surgery? No, not yet at least.
Topics: Anesthetics, Inhalation; Cardiotonic Agents; Enflurane; Evidence-Based Medicine; Halothane; Humans; | 2008 |
Comparative effects of halothane, enflurane, isoflurane and sevoflurane on function and metabolism in the ischaemic rat heart.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Cardiac Output; Coronary Circulation; Enfl | 1995 |
Isoflurane, compared to halothane or enflurane, causes increased lactate production but no transmural coronary steal during myocardial ischemia in swine.
Topics: Animals; Coronary Vessels; Enflurane; Halothane; Isoflurane; Lactates; Myocardial Ischemia; Stimulat | 1993 |
Actions of volatile anesthetics on ischemic and nonischemic Purkinje fibers in the canine heart: regional action potential characteristics.
Topics: Action Potentials; Anesthetics; Animals; Dogs; Enflurane; Halothane; Isoflurane; Myocardial Infarcti | 1993 |