Page last updated: 2024-10-26

enflurane and Muscle Contraction

enflurane has been researched along with Muscle Contraction in 40 studies

Enflurane: An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate.
enflurane : An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" In nine other dogs, the contractile response to a brief period of apnea was assessed in three planes of anesthesia, namely 0% (baseline anesthesia with pentobarbital), 1%, and 2% of inspired enflurane concentration."3.67Effects of enflurane on contractile response of canine trachealis muscle. ( Hagiya, M; Kochi, T; Mizuguchi, T, 1989)
"A two years, ten months old male with dermatomyositis was anaesthetized with enflurane, nitrous oxide and oxygen by mask followed by intravenous succinylcholine to facilitate endotracheal intubation."3.67Anaesthetic management of a child with dermatomyositis. ( Finholt, DA; Johns, RA; Stirt, JA, 1986)
"Mivacurium infusion was titrated to give a 90% block of first twitch height."2.68Recovery from mivacurium block with or without anticholinesterase following continuous infusion in obstetric patients. ( Chan, AM; Hui, TW; Jan, GS; Lo, JW; Tong, WN, 1996)
"Pancuronium 3 mg/70 kg was antagonized with neostigmine 2."2.65Impaired neostigmine antagonism of pancuronium during enflurane anaesthesia in man. ( Bevan, DR; Delisle, S, 1982)
"Halothane was the strongest discriminator for malignant hyperthermia in the in-vitro contracture tests."1.37In-vitro contracture testing for susceptibility to malignant hyperthermia: can halothane be replaced? ( Anetseder, M; Kranke, P; Metterlein, T; Roewer, N; Schuster, F, 2011)
" The preparations were then exposed to up to 4 vol% volatile agent incrementally to generate a cumulative dose-response curve, and the subsequent frequency of peristaltic contractions was determined."1.29Volatile anesthetics decrease peristalsis in the guinea pig ureter. ( Attele, A; Moss, J; Núñez, R; Toledano, A; Young, CJ, 1994)
"Enflurane has similar mechanisms of action in aorta and femoral artery: blocking Ca2+ influx, and causing, at least in part, Ca2+ release from the sarcoplasmic reticulum through the ryanodine-receptor channel."1.29Mechanisms of action of enflurane on vascular smooth muscle. Comparison of rabbit aorta and femoral artery. ( Chang, YI; Su, JY; Tang, LJ, 1994)
"Neostigmine was administered at either 10% recovery of the twitch height (TH10) at the adductor pollicis muscle (n = 14) or upon reappearance of the first response at the orbicularis oculi muscle (OO1) after train-of-four (TOF) stimulation (n = 16), the latter representing a deeper degree of neuromuscular blockade."1.29Effect of neostigmine at different levels of mivacurium-induced neuromuscular blockade. ( Baras, E; Camatte, S; Chandon, M; Just, B; Lienhart, A; Trévien, V, 1995)
"Enflurane enhanced the increase of light signal observed in rapid cooling contracture."1.27Effects of enflurane on excitation-contraction coupling in frog skeletal muscle fibers. ( Konishi, M; Kurihara, S; Miyagishima, T; Sakai, T, 1984)
"Enflurane has a significantly greater synergistic effect than halothane."1.27Differential increase in potency of neuromuscular blocking agents by enflurane and halothane. ( Schuh, FT, 1983)
"Ether was associated with periods of intense activity throughout anaesthesia and this activity persisted after recovery of consciousness."1.26Effects of inhalation anaesthetic agents on the electrical and mechanical activity of the rat duodenum. ( Balfour, TW; Hardcastle, JD; Healy, TE; Wright, JW, 1982)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199021 (52.50)18.7374
1990's17 (42.50)18.2507
2000's1 (2.50)29.6817
2010's1 (2.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Metterlein, T1
Schuster, F1
Kranke, P1
Roewer, N1
Anetseder, M1
Nishina, K1
Mikawa, K1
Kodama, SI1
Kagawa, T1
Uesugi, T1
Obara, H1
Kurihara, S1
Konishi, M1
Miyagishima, T5
Sakai, T1
Iwatsuki, N2
Koga, Y2
Amaha, K4
Schuh, FT1
Delisle, S1
Bevan, DR1
Wright, JW1
Healy, TE1
Balfour, TW1
Hardcastle, JD1
Akata, T1
Boyle, WA1
Young, CJ1
Attele, A1
Toledano, A1
Núñez, R1
Moss, J1
Su, JY1
Chang, YI1
Tang, LJ1
Saitoh, Y2
Toyooka, H1
Puttick, RM1
Terrar, DA1
Yamakage, M1
Kohro, S1
Kawamata, T1
Namiki, A1
Trévien, V1
Lienhart, A1
Just, B1
Chandon, M1
Baras, E1
Camatte, S1
Jan, GS1
Tong, WN1
Chan, AM1
Hui, TW1
Lo, JW1
Tanaka, H1
Fujii, Y1
Makita, K1
Waud, BE1
Waud, DR1
Munson, ES1
Embro, WJ1
Peduto, VA1
Pieraccioli, E1
Carbonetto, F1
Novelli, GP1
Klide, AM1
Isono, S3
Kochi, T3
Ide, T3
Sugimori, K1
Mizuguchi, T4
Nishino, T2
Tagliente, TM1
Evans, PJ1
Ben-Harari, RR1
Nishiwaki, T1
Oka, N2
Blaise, GA1
Hughes, JM1
Sill, JC1
Buluran, JN1
Caille, G1
Baele, P1
Housmans, PR1
Kobayashi, Y1
Yoshida, K1
Noguchi, M1
Wakasugi, Y1
Ito, H1
Okabe, E1
Lumb, AB1
Calder, I1
Hagiya, M1
O'Hara, DA1
Fragen, RJ1
Shanks, CA1
Reynolds, PI1
Fang, WB1
VanDerSpek, AF1
Shibata, T1
Blanck, TJ1
Sagawa, K1
Hunter, W1
Okumura, K1
Yamamato, M1
Lindgren, L1
Saarnivaara, L1
Condon, RE1
Cowles, V1
Ekbom, GA1
Schulte, WJ1
Hess, G1
Johns, RA1
Finholt, DA1
Stirt, JA1

Trials

5 trials available for enflurane and Muscle Contraction

ArticleYear
Impaired neostigmine antagonism of pancuronium during enflurane anaesthesia in man.
    British journal of anaesthesia, 1982, Volume: 54, Issue:4

    Topics: Adult; Aged; Anesthesia, Inhalation; Drug Interactions; Enflurane; Halothane; Humans; Middle Aged; M

1982
Recovery from mivacurium block with or without anticholinesterase following continuous infusion in obstetric patients.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:5

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intrav

1996
Post-tetanic burst count and train-of-four during recovery from vecuronium-induced intense neuromuscular block under different types of anaesthesia.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:5

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalat

1998
Comparison of visual and measured train-of-four recovery after vecuronium-induced neuromuscular blockade using two anaesthetic techniques.
    British journal of anaesthesia, 1986, Volume: 58, Issue:11

    Topics: Anesthesia, General; Anesthesia, Inhalation; Enflurane; Female; Humans; Male; Muscle Contraction; Ne

1986
Enflurane inhibits muscle fasciculations caused by suxamethonium in children.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:6

    Topics: Child; Child, Preschool; Enflurane; Humans; Muscle Contraction; Muscles; Otorhinolaryngologic Diseas

1986

Other Studies

35 other studies available for enflurane and Muscle Contraction

ArticleYear
In-vitro contracture testing for susceptibility to malignant hyperthermia: can halothane be replaced?
    European journal of anaesthesiology, 2011, Volume: 28, Issue:4

    Topics: Anesthetics, Inhalation; Biopsy; Case-Control Studies; Desflurane; Dose-Response Relationship, Drug;

2011
The effects of enflurane, isoflurane, and intravenous anesthetics on rat diaphragmatic function and fatigability.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:6

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Diaphragm; Electric Stimulation; Enflura

2003
Effects of enflurane on excitation-contraction coupling in frog skeletal muscle fibers.
    Pflugers Archiv : European journal of physiology, 1984, Volume: 402, Issue:4

    Topics: Action Potentials; Aequorin; Animals; Caffeine; Calcium; Enflurane; Glycerol; Hindlimb; Membrane Pot

1984
[Contracture responses of the muscle from a patient with malignant hyperthermia to drugs].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:7

    Topics: Adolescent; Diltiazem; Enflurane; Halothane; Humans; In Vitro Techniques; Male; Malignant Hypertherm

1984
[Effects of enflurane on contractile system of skeletal muscle--effects on contractile protein].
    Masui. The Japanese journal of anesthesiology, 1983, Volume: 32, Issue:6

    Topics: Actomyosin; Animals; Calcium; Enflurane; Muscle Contraction; Muscle Proteins; Rabbits; Rana catesbei

1983
[Effects of enflurane on contraction of skeletal muscles. Effects on internal membrane system].
    Masui. The Japanese journal of anesthesiology, 1983, Volume: 32, Issue:11

    Topics: Animals; Calcium; Enflurane; Muscle Contraction; Rana catesbeiana; Sarcoplasmic Reticulum

1983
Enflurane induces contracture of in vitro muscle from a patient with malignant hyperthermia.
    The Tohoku journal of experimental medicine, 1983, Volume: 140, Issue:2

    Topics: Enflurane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction

1983
Differential increase in potency of neuromuscular blocking agents by enflurane and halothane.
    International journal of clinical pharmacology, therapy, and toxicology, 1983, Volume: 21, Issue:8

    Topics: Adult; Aged; Anesthesia, Inhalation; Dose-Response Relationship, Drug; Drug Synergism; Enflurane; Fe

1983
Effects of inhalation anaesthetic agents on the electrical and mechanical activity of the rat duodenum.
    British journal of anaesthesia, 1982, Volume: 54, Issue:11

    Topics: Action Potentials; Anesthesia, Inhalation; Animals; Duodenum; Enflurane; Ether; Ethyl Ethers; Gastro

1982
Volatile anesthetic actions on contractile proteins in membrane-permeabilized small mesenteric arteries.
    Anesthesiology, 1995, Volume: 82, Issue:3

    Topics: Animals; Calcium; Cell Membrane Permeability; Contractile Proteins; Enflurane; Escin; Halothane; In

1995
Volatile anesthetics decrease peristalsis in the guinea pig ureter.
    Anesthesiology, 1994, Volume: 81, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Enflurane; Guinea Pigs; Halothane; In Vitro Techniques; I

1994
Mechanisms of action of enflurane on vascular smooth muscle. Comparison of rabbit aorta and femoral artery.
    Anesthesiology, 1994, Volume: 81, Issue:3

    Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Endothelium, Vascular; Enflurane; Femoral Artery; In Vi

1994
Relationship between post-tetanic twitch and single twitch response after administration of vecuronium.
    British journal of anaesthesia, 1993, Volume: 71, Issue:3

    Topics: Adult; Anesthesia, Inhalation; Anesthetics; Enflurane; Ethers; Female; Halothane; Humans; Isoflurane

1993
Differential effects of propofol and enflurane on contractions dependent on calcium derived from the sarcoplasmic reticulum of guinea pig isolated papillary muscles.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:1

    Topics: Animals; Calcium; Electric Stimulation; Enflurane; Guinea Pigs; Muscle Contraction; Papillary Muscle

1993
Inhibitory effects of four inhaled anesthetics on canine tracheal smooth muscle contraction and intracellular Ca2+ concentration.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:1

    Topics: Anesthetics; Animals; Calcium; Carbachol; Dogs; Drug Interactions; Enflurane; Ethers; Halothane; Iso

1993
Effect of neostigmine at different levels of mivacurium-induced neuromuscular blockade.
    Acta anaesthesiologica Scandinavica. Supplementum, 1995, Volume: 106

    Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cholinesterase Inhibitor

1995
Effects of volatile anesthetics on directly and indirectly stimulated skeletal muscle.
    Anesthesiology, 1979, Volume: 50, Issue:2

    Topics: Anesthetics; Animals; Electric Stimulation; Enflurane; Ether; Ethers; Guinea Pigs; Halothane; In Vit

1979
Enflurane, isoflurane, and halothane and isolated human uterine muscle.
    Anesthesiology, 1977, Volume: 46, Issue:1

    Topics: Adult; Depression, Chemical; Enflurane; Female; Halothane; Humans; Isoflurane; Methyl Ethers; Muscle

1977
[Modifications in the contractibility of the isolated rat aorta induced by halothane and enflurane].
    Minerva anestesiologica, 1975, Volume: 41, Issue:9

    Topics: Animals; Aorta; Enflurane; Halothane; Methyl Ethers; Muscle Contraction; Rats

1975
Cardiopulmonary effects of enflurane and isoflurane in the dog.
    American journal of veterinary research, 1976, Volume: 37, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Aorta; Blood Pressure; Cardiac Output; Dogs; Enflurane; Female; Hea

1976
Differential effects of vecuronium on diaphragm and geniohyoid muscle in anaesthetized dogs.
    British journal of anaesthesia, 1992, Volume: 68, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Biomechanical Phenomena; Diaphragm; Dogs; Enflurane; Hyoid Bone; Is

1992
Halothane- and enflurane-induced inhibition of phasic responses to carbachol in isolated guinea pig trachea.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:1

    Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Enflurane; Guinea Pigs; Halothane; Kinetics; M

1992
[Effects of volatile anesthetics on crossbridge mechanism of skeletal muscle--effects on the crossbridge in contraction].
    Masui. The Japanese journal of anesthesiology, 1991, Volume: 40, Issue:11

    Topics: Animals; Enflurane; Halothane; In Vitro Techniques; Muscle Contraction; Muscles; Ranidae; Rats

1991
Attenuation of contraction of isolated canine coronary arteries by enflurane and halothane.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:1

    Topics: Animals; Calcium; Calcium Channels; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Enflur

1991
The effects of halothane, enflurane, and isoflurane on the length-tension relation of the isolated ventricular papillary muscle of the ferret.
    Anesthesiology, 1991, Volume: 74, Issue:2

    Topics: Animals; Depression, Chemical; Enflurane; Ferrets; Halothane; In Vitro Techniques; Isoflurane; Male;

1991
Different effects of halothane and enflurane on diaphragmatic contractility in vivo.
    Anesthesia and analgesia, 1990, Volume: 70, Issue:4

    Topics: Animals; Blood Pressure; Diaphragm; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; En

1990
Effect of enflurane on contractile reactivity in isolated canine mesenteric arteries and veins.
    Anesthesia and analgesia, 1990, Volume: 70, Issue:5

    Topics: Animals; Dogs; Drug Interactions; Enflurane; Female; In Vitro Techniques; Male; Mesenteric Arteries;

1990
Effects of sevoflurane and enflurane on contractility of canine diaphragm.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2

    Topics: Anesthetics; Animals; Diaphragm; Dogs; Dose-Response Relationship, Drug; Enflurane; Ethers; Methyl E

1990
'Cured' myasthenia gravis and neuromuscular blockade.
    Anaesthesia, 1989, Volume: 44, Issue:10

    Topics: Adult; Anesthesia, General; Drug Synergism; Enflurane; Female; Humans; Muscle Contraction; Myastheni

1989
Effects of enflurane on contractile response of canine trachealis muscle.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:1

    Topics: Animals; Apnea; Blood Pressure; Dogs; Electric Stimulation; Enflurane; Laryngeal Nerves; Lung; Muscl

1989
The onset of ablation of the evoked adductor pollicis muscle twitch in children: a clinical perspective.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1988, Volume: 35, Issue:6

    Topics: Adolescent; Anesthesia, Inhalation; Child; Child, Preschool; Depression, Chemical; Electric Stimulat

1988
The effect of halothane, enflurane, and isoflurane on the dynamic stiffness of rabbit papillary muscle.
    Anesthesiology, 1989, Volume: 70, Issue:3

    Topics: Animals; Barium; Dose-Response Relationship, Drug; Enflurane; Halothane; Isoflurane; Muscle Contract

1989
[Direct action of enflurane on the contractile element in skeletal muscle of guinea-pig].
    Masui. The Japanese journal of anesthesiology, 1987, Volume: 36, Issue:7

    Topics: Animals; Caffeine; Calcium; Enflurane; Guinea Pigs; In Vitro Techniques; Muscle Contraction

1987
Effects of halothane, enflurane, and nitrous oxide on colon motility.
    Surgery, 1987, Volume: 101, Issue:1

    Topics: Animals; Colon; Electrophysiology; Enflurane; Gastrointestinal Motility; Halothane; Macaca; Muscle C

1987
Anaesthetic management of a child with dermatomyositis.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:1

    Topics: Anesthesia, General; Child, Preschool; Dermatomyositis; Enflurane; Humans; Muscle Contraction; Neuro

1986